Search Results - "Ibba, Maria L."
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Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation
Published in Nature communications (06-01-2023)“…DNA methylation is a fundamental epigenetic modification regulating gene expression. Aberrant DNA methylation is the most common molecular lesion in cancer…”
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Advances in Oligonucleotide Aptamers for NSCLC Targeting
Published in International journal of molecular sciences (23-08-2020)“…Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer worldwide, with the highest incidence in developed countries. NSCLC patients often…”
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STAT3 silencing by an aptamer-based strategy hampers the crosstalk between NSCLC cells and cancer-associated fibroblasts
Published in Molecular therapy. Nucleic acids (13-06-2023)“…The identification of new effective therapeutic options for non-small-cell lung cancer (NSCLC) represents a crucial challenge in oncology. Recent studies…”
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Advances in mRNA non-viral delivery approaches
Published in Advanced drug delivery reviews (01-10-2021)“…[Display omitted] Messenger RNAs (mRNAs) present a great potential as therapeutics for the treatment and prevention of a wide range of human pathologies,…”
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Emerging Therapeutic RNAs for the Targeting of Cancer Associated Fibroblasts
Published in Cancers (26-05-2020)“…Tumor mass consists of a complex ensemble of malignant cancer cells and a wide variety of resident and infiltrating cells, secreted factors, and extracellular…”
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