Search Results - "Ibazizene, Méziane"

Chemical Delivery System of Metaiodobenzylguanidine (MIBG) to the Central Nervous System by Gourand, Fabienne, Mercey, Guillaume, Ibazizène, Méziane, Tirel, Olivier, Henry, Joël, Levacher, Vincent, Perrio, Cécile, Barré, Louisa

“…The aim of the present investigation was to apply a chemical delivery system (CDS) to MIBG (4) with the purpose of delivering this drug to the CNS. Compound 4…”
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Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: MRI and 18F-FDG PET Quantitative Analysis Using FreeSurfer by Ibazizene, Méziane, Payoux, Pierre, Barré, Louisa, Camus, Vincent, Guilloteau, Denis, Ribeiro, Maria-Joao, Vercouillie, Johnny, Vierron, Emilie, Beaufils, Emilie, Cottier, Jean-Philippe, Mondon, Karl, Hommet, Caroline, Destrieux, Christophe, Bailly, Matthieu, Voisin, Thierry

“…Objective. The objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with Alzheimer’s…”
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Debenzylation of Tertiary Amines Using Phosgene or Triphosgene:  An Efficient and Rapid Procedure for the Preparation of Carbamoyl Chlorides and Unsymmetrical Ureas. Application in Carbon-11 Chemistry by Lemoucheux, Laurent, Rouden, Jacques, Ibazizene, Méziane, Sobrio, Franck, Lasne, Marie-Claire

“…Efficient and rapid preparations of carbamoyl chlorides and unsymmetrical ureas from tertiary amines and phosgene or its safe equivalent triphosgene…”
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Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia by La Joie, Renaud, Perrotin, Audrey, Barré, Louisa, Hommet, Caroline, Mézenge, Florence, Ibazizene, Méziane, Camus, Vincent, Abbas, Ahmed, Landeau, Brigitte, Guilloteau, Denis, de La Sayette, Vincent, Eustache, Francis, Desgranges, Béatrice, Chételat, Gaël

“…Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described hallmarks of Alzheimer's disease, but their relationships are…”
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Evaluation of Specific Binding of [11C]RTI-97 to Kappa Opioid Receptor by Autoradiography and PET Imaging in Rat by Fillesoye, Fabien, Ibazizène, Méziane, Marie, Nicolas, Noble, Florence, Perrio, Cécile

“…Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases and to help the development of drugs especially…”
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Multimodal evaluation of hypoxia in brain metastases of lung cancer and interest of hypoxia image-guided radiotherapy by Corroyer-Dulmont, Aurélien, Valable, Samuel, Fantin, Jade, Chatre, Laurent, Toutain, Jérôme, Teulier, Sylvain, Bazille, Céline, Letissier, Elise, Levallet, Jérôme, Divoux, Didier, Ibazizène, Méziane, Guillouet, Stéphane, Perrio, Cécile, Barré, Louisa, Serres, Sébastien, Sibson, Nicola R., Chapon, Françoise, Levallet, Guénaëlle, Bernaudin, Myriam

“…Lung cancer patients frequently develop brain metastases (BM). Despite aggressive treatment including neurosurgery and external-radiotherapy, overall survival…”
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Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer's Disease and Mild Cognitive Impairment: MRI and (18)F-FDG PET Quantitative Analysis Using FreeSurfer by Bailly, Matthieu, Destrieux, Christophe, Hommet, Caroline, Mondon, Karl, Cottier, Jean-Philippe, Beaufils, Emilie, Vierron, Emilie, Vercouillie, Johnny, Ibazizene, Méziane, Voisin, Thierry, Payoux, Pierre, Barré, Louisa, Camus, Vincent, Guilloteau, Denis, Ribeiro, Maria-Joao

“…The objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with Alzheimer's disease (AD) and…”
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Multimodal imaging based on MRI and PET reveals [18F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma by Corroyer-Dulmont, Aurélien, Pérès, Elodie A., Gérault, Aurélie N., Savina, Ariel, Bouquet, Fanny, Divoux, Didier, Toutain, Jérôme, Ibazizène, Méziane, MacKenzie, Eric T., Barré, Louisa, Bernaudin, Myriam, Petit, Edwige, Valable, Samuel

“…Purpose The primary objective of this study was to compare the ability of PET and MRI biomarkers to predict treatment efficacy in a preclinical model of…”
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Dihydroquinoline Carbamate Derivatives as “Bio-oxidizable” Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [11C] Radiosynthesis and Biological Evaluation by Bohn, Pierre, Gourand, Fabienne, Papamicaël, Cyril, Ibazizène, Méziane, Dhilly, Martine, Gembus, Vincent, Alix, Florent, Ţînţaş, Mihaela-Liliana, Marsais, Francis, Barré, Louisa, Levacher, Vincent

“…With the aim of improving the efficiency of marketed acetylcholinesterase (AChE) inhibitors in the symptomatic treatment of Alzheimer’s disease, plagued by…”
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Delivering FLT to the Central Nervous System by Means of a Promising Targeting System: Synthesis, [11C]Radiosynthesis, and in Vivo Evaluation by Gourand, Fabienne, Ţînţaş, Mihaela-Liliana, Henry, Axelle, Ibazizène, Méziane, Dhilly, Martine, Fillesoye, Fabien, Papamicaël, Cyril, Levacher, Vincent, Barré, Louisa

“…The development of delivery systems to transport some specific radiotracers across the blood-brain barrier (BBB) needs to be investigated for brain imaging…”
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Chemical Delivery System of MIBG to the Central Nervous System: Synthesis, 11C‑Radiosynthesis, and in Vivo Evaluation by Gourand, Fabienne, Patin, Delphine, Henry, Axelle, Ibazizène, Méziane, Dhilly, Martine, Fillesoye, Fabien, Tirel, Olivier, Tintas, Mihaela-Liliana, Papamicaël, Cyril, Levacher, Vincent, Barré, Louisa

“…The norepinephrine transporter (NET) plays an important role in neurotransmission and is involved in a multitude of psychiatric and neurodegenerative diseases…”
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[ 18 F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [ 18 F]FDG in human xenograft models by Hovhannisyan, Narinée, Fillesoye, Fabien, Guillouet, Stéphane, Ibazizene, Méziane, Toutain, Jérôme, Gourand, Fabienne, Valable, Samuel, Plancoulaine, Benoit, Barré, Louisa

“…This paper investigated whether positron emission tomography (PET) imaging with [ F]fludarabine ([ F]FDB) can help to differentiate central nervous system…”
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Chemical Delivery System of MIBG to the Central Nervous System: Synthesis, 11 C-Radiosynthesis, and in Vivo Evaluation by Gourand, Fabienne, Patin, Delphine, Henry, Axelle, Ibazizène, Méziane, Dhilly, Martine, Fillesoye, Fabien, Tirel, Olivier, Tintas, Mihaela-Liliana, Papamicaël, Cyril, Levacher, Vincent, Barré, Louisa

“…The norepinephrine transporter (NET) plays an important role in neurotransmission and is involved in a multitude of psychiatric and neurodegenerative diseases…”
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Evaluation of Specific Binding of [11C]RTI-97 to KOR by Autoradiog-raphy and PET Imaging in Rat by Fillesoye, Fabien, Ibazizene, Méziane, Marie, Nicolas, Noble, Florence, Perrio, Cécile

“…Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases, and to help the development of drugs…”
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Detection of glioblastoma response to temozolomide combined with bevacizumab based on μMRI and μPET imaging reveals [18F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy by Corroyer-Dulmont, Aurélien, Pérès, Elodie A, Petit, Edwige, Guillamo, Jean-Sébastien, Varoqueaux, Nathalie, Roussel, Simon, Toutain, Jérôme, Divoux, Didier, MacKenzie, Eric T, Delamare, Jérôme, Ibazizène, Méziane, Lecocq, Myriam, Jacobs, Andréas H, Barré, Louisa, Bernaudin, Myriam, Valable, Samuel

“…The individualized care of glioma patients ought to benefit from imaging biomarkers as precocious predictors of therapeutic efficacy. Contrast enhanced MRI and…”
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64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study by Pérès, Elodie A., Toutain, Jérôme, Paty, Louis-Paul, Divoux, Didier, Ibazizène, Méziane, Guillouet, Stéphane, Barré, Louisa, Vidal, Aurélien, Cherel, Michel, Bourgeois, Mickaël, Bernaudin, Myriam, Valable, Samuel

“…Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu ( 64 Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However,…”
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Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: MRI and 18 F-FDG PET Quantitative Analysis Using FreeSurfer by Bailly, Matthieu, Destrieux, Christophe, Hommet, Caroline, Mondon, Karl, Cottier, Jean-Philippe, Beaufils, Emilie, Vierron, Emilie, Vercouillie, Johnny, Ibazizene, Meziane, Voisin, Thierry, Payoux, Pierre, Barre, Louisa, Camus, Vincent, Guilloteau, Denis, Ribeiro, Maria-Joao

“…Objective. The objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with Alzheimer’s…”
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sup 18^F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients by Chantepie, Sylvain, Hovhannisyan, Narinée, Guillouet, Stéphane, Pelage, Jean-Pierre, Ibazizene, Méziane, Bodet-Milin, Caroline, Carlier, Thomas, Gac, Anne-Claire, Réboursière, Emilie, Vilque, Jean-Pierre, Kraeber-Bodéré, Françoise, Manrique, Alain, Damaj, Gandhi, Leporrier, Michel, Barré, Louisa

“…This was the first-in-humans clinical study of 18F-fludarabine, which is a radiopharmaceutical for PET imaging in lymphoma, for which many issues remain…”
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Detection of glioblastoma response to temozolomide combined with bevacizumab based on µMRI and µPET imaging reveals [18F]-fluoro-l-thymidine as an early and robust predictive marker for treatment efficacy by Corroyer-Dulmont, Aurélien, Pérès, Elodie A., Petit, Edwige, Guillamo, Jean-Sébastien, Varoqueaux, Nathalie, Roussel, Simon, Toutain, Jérôme, Divoux, Didier, MacKenzie, Eric T., Delamare, Jérôme, Ibazizène, Méziane, Lecocq, Myriam, Jacobs, Andréas H., Barré, Louisa, Bernaudin, Myriam, Valable, Samuel

“…The individualized care of glioma patients ought to benefit from imaging biomarkers as precocious predictors of therapeutic efficacy. Contrast enhanced MRI and…”
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18 F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients by Chantepie, Sylvain, Hovhannisyan, Narinée, Guillouet, Stéphane, Pelage, Jean-Pierre, Ibazizene, Méziane, Bodet-Milin, Caroline, Carlier, Thomas, Gac, Anne-Claire, Réboursière, Emilie, Vilque, Jean-Pierre, Kraeber-Bodéré, Françoise, Manrique, Alain, Damaj, Gandhi, Leporrier, Michel, Barré, Louisa

“…This was the first-in-humans clinical study of F-fludarabine, which is a radiopharmaceutical for PET imaging in lymphoma, for which many issues remain…”
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