Search Results - "Ibazizène, Méziane"

Evaluation of Specific Binding of [11C]RTI-97 to Kappa Opioid Receptor by Autoradiography and PET Imaging in Rat by Fillesoye, Fabien, Ibazizène, Méziane, Marie, Nicolas, Noble, Florence, Perrio, Cécile

“…Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases and to help the development of drugs especially…”
Get full text

Dihydroquinoline Carbamate Derivatives as “Bio-oxidizable” Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [11C] Radiosynthesis and Biological Evaluation by Bohn, Pierre, Gourand, Fabienne, Papamicaël, Cyril, Ibazizène, Méziane, Dhilly, Martine, Gembus, Vincent, Alix, Florent, Ţînţaş, Mihaela-Liliana, Marsais, Francis, Barré, Louisa, Levacher, Vincent

“…With the aim of improving the efficiency of marketed acetylcholinesterase (AChE) inhibitors in the symptomatic treatment of Alzheimer’s disease, plagued by…”
Get full text

Delivering FLT to the Central Nervous System by Means of a Promising Targeting System: Synthesis, [11C]Radiosynthesis, and in Vivo Evaluation by Gourand, Fabienne, Ţînţaş, Mihaela-Liliana, Henry, Axelle, Ibazizène, Méziane, Dhilly, Martine, Fillesoye, Fabien, Papamicaël, Cyril, Levacher, Vincent, Barré, Louisa

“…The development of delivery systems to transport some specific radiotracers across the blood-brain barrier (BBB) needs to be investigated for brain imaging…”
Get full text

Chemical Delivery System of MIBG to the Central Nervous System: Synthesis, 11C‑Radiosynthesis, and in Vivo Evaluation by Gourand, Fabienne, Patin, Delphine, Henry, Axelle, Ibazizène, Méziane, Dhilly, Martine, Fillesoye, Fabien, Tirel, Olivier, Tintas, Mihaela-Liliana, Papamicaël, Cyril, Levacher, Vincent, Barré, Louisa

“…The norepinephrine transporter (NET) plays an important role in neurotransmission and is involved in a multitude of psychiatric and neurodegenerative diseases…”
Get full text

Chemical Delivery System of MIBG to the Central Nervous System: Synthesis, 11 C-Radiosynthesis, and in Vivo Evaluation by Gourand, Fabienne, Patin, Delphine, Henry, Axelle, Ibazizène, Méziane, Dhilly, Martine, Fillesoye, Fabien, Tirel, Olivier, Tintas, Mihaela-Liliana, Papamicaël, Cyril, Levacher, Vincent, Barré, Louisa

“…The norepinephrine transporter (NET) plays an important role in neurotransmission and is involved in a multitude of psychiatric and neurodegenerative diseases…”
Get full text

Detection of glioblastoma response to temozolomide combined with bevacizumab based on μMRI and μPET imaging reveals [18F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy by Corroyer-Dulmont, Aurélien, Pérès, Elodie A, Petit, Edwige, Guillamo, Jean-Sébastien, Varoqueaux, Nathalie, Roussel, Simon, Toutain, Jérôme, Divoux, Didier, MacKenzie, Eric T, Delamare, Jérôme, Ibazizène, Méziane, Lecocq, Myriam, Jacobs, Andréas H, Barré, Louisa, Bernaudin, Myriam, Valable, Samuel

“…The individualized care of glioma patients ought to benefit from imaging biomarkers as precocious predictors of therapeutic efficacy. Contrast enhanced MRI and…”
Get full text

64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study by Pérès, Elodie A., Toutain, Jérôme, Paty, Louis-Paul, Divoux, Didier, Ibazizène, Méziane, Guillouet, Stéphane, Barré, Louisa, Vidal, Aurélien, Cherel, Michel, Bourgeois, Mickaël, Bernaudin, Myriam, Valable, Samuel

“…Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu ( 64 Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However,…”
Get full text

Detection of glioblastoma response to temozolomide combined with bevacizumab based on µMRI and µPET imaging reveals [18F]-fluoro-l-thymidine as an early and robust predictive marker for treatment efficacy by Corroyer-Dulmont, Aurélien, Pérès, Elodie A., Petit, Edwige, Guillamo, Jean-Sébastien, Varoqueaux, Nathalie, Roussel, Simon, Toutain, Jérôme, Divoux, Didier, MacKenzie, Eric T., Delamare, Jérôme, Ibazizène, Méziane, Lecocq, Myriam, Jacobs, Andréas H., Barré, Louisa, Bernaudin, Myriam, Valable, Samuel

“…The individualized care of glioma patients ought to benefit from imaging biomarkers as precocious predictors of therapeutic efficacy. Contrast enhanced MRI and…”
Get full text

Chemical Delivery System of Metaiodobenzylguanidine (MIBG) to the Central Nervous System by Gourand, Fabienne, Mercey, Guillaume, Ibazizène, Méziane, Tirel, Olivier, Henry, Joël, Levacher, Vincent, Perrio, Cécile, Barré, Louisa

“…The aim of the present investigation was to apply a chemical delivery system (CDS) to MIBG (4) with the purpose of delivering this drug to the CNS. Compound 4…”
Get full text

Radiosynthesis of [11C]EHT1610, a potential radioligand for quantification of cerebral DYRK1A by PET imaging by POUTREL, Pauline, Fillesoye, Fabien, Ibazizène, Méziane, Fruit, Corinne, Besson, Thierry, Perrio, Cecile, Gourand, Fabienne

Get full text

P-083 - Radiosynthesis of [11C]EHT1610, a potential radioligand for quantification of cerebral DYRK1A by PET imaging by POUTREL, Pauline, Fillesoye, Fabien, Ibazizène, Méziane, Fruit, Corinne, Besson, Thierry, Perrio, Cecile, Gourand, Fabienne

Get full text

Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: MRI and 18F-FDG PET Quantitative Analysis Using FreeSurfer by Ibazizene, Méziane, Payoux, Pierre, Barré, Louisa, Camus, Vincent, Guilloteau, Denis, Ribeiro, Maria-Joao, Vercouillie, Johnny, Vierron, Emilie, Beaufils, Emilie, Cottier, Jean-Philippe, Mondon, Karl, Hommet, Caroline, Destrieux, Christophe, Bailly, Matthieu, Voisin, Thierry

“…Objective. The objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with Alzheimer’s…”
Get full text

Debenzylation of Tertiary Amines Using Phosgene or Triphosgene:  An Efficient and Rapid Procedure for the Preparation of Carbamoyl Chlorides and Unsymmetrical Ureas. Application in Carbon-11 Chemistry by Lemoucheux, Laurent, Rouden, Jacques, Ibazizene, Méziane, Sobrio, Franck, Lasne, Marie-Claire

“…Efficient and rapid preparations of carbamoyl chlorides and unsymmetrical ureas from tertiary amines and phosgene or its safe equivalent triphosgene…”
Get full text

Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia by La Joie, Renaud, Perrotin, Audrey, Barré, Louisa, Hommet, Caroline, Mézenge, Florence, Ibazizene, Méziane, Camus, Vincent, Abbas, Ahmed, Landeau, Brigitte, Guilloteau, Denis, de La Sayette, Vincent, Eustache, Francis, Desgranges, Béatrice, Chételat, Gaël

“…Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described hallmarks of Alzheimer's disease, but their relationships are…”
Get full text

64 Cu-ATSM/ 64 Cu-Cl 2 and their relationship to hypoxia in glioblastoma: a preclinical study by Pérès, Elodie A, Toutain, Jérôme, Paty, Louis-Paul, Divoux, Didier, Ibazizène, Méziane, Guillouet, Stéphane, Barré, Louisa, Vidal, Aurélien, Cherel, Michel, Bourgeois, Mickaël, Bernaudin, Myriam, Valable, Samuel

“…Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu ( Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However, various…”
Get full text

Multimodal evaluation of hypoxia in brain metastases of lung cancer and interest of hypoxia image-guided radiotherapy by Corroyer-Dulmont, Aurélien, Valable, Samuel, Fantin, Jade, Chatre, Laurent, Toutain, Jérôme, Teulier, Sylvain, Bazille, Céline, Letissier, Elise, Levallet, Jérôme, Divoux, Didier, Ibazizène, Méziane, Guillouet, Stéphane, Perrio, Cécile, Barré, Louisa, Serres, Sébastien, Sibson, Nicola R., Chapon, Françoise, Levallet, Guénaëlle, Bernaudin, Myriam

“…Lung cancer patients frequently develop brain metastases (BM). Despite aggressive treatment including neurosurgery and external-radiotherapy, overall survival…”
Get full text

Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer's Disease and Mild Cognitive Impairment: MRI and (18)F-FDG PET Quantitative Analysis Using FreeSurfer by Bailly, Matthieu, Destrieux, Christophe, Hommet, Caroline, Mondon, Karl, Cottier, Jean-Philippe, Beaufils, Emilie, Vierron, Emilie, Vercouillie, Johnny, Ibazizene, Méziane, Voisin, Thierry, Payoux, Pierre, Barré, Louisa, Camus, Vincent, Guilloteau, Denis, Ribeiro, Maria-Joao

“…The objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with Alzheimer's disease (AD) and…”
Get full text

Multimodal imaging based on MRI and PET reveals [18F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma by Corroyer-Dulmont, Aurélien, Pérès, Elodie A., Gérault, Aurélie N., Savina, Ariel, Bouquet, Fanny, Divoux, Didier, Toutain, Jérôme, Ibazizène, Méziane, MacKenzie, Eric T., Barré, Louisa, Bernaudin, Myriam, Petit, Edwige, Valable, Samuel

“…Purpose The primary objective of this study was to compare the ability of PET and MRI biomarkers to predict treatment efficacy in a preclinical model of…”
Get full text

[ 18 F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [ 18 F]FDG in human xenograft models by Hovhannisyan, Narinée, Fillesoye, Fabien, Guillouet, Stéphane, Ibazizene, Méziane, Toutain, Jérôme, Gourand, Fabienne, Valable, Samuel, Plancoulaine, Benoit, Barré, Louisa

“…This paper investigated whether positron emission tomography (PET) imaging with [ F]fludarabine ([ F]FDB) can help to differentiate central nervous system…”
Get full text

Evaluation of Specific Binding of [11C]RTI-97 to KOR by Autoradiog-raphy and PET Imaging in Rat by Fillesoye, Fabien, Ibazizene, Méziane, Marie, Nicolas, Noble, Florence, Perrio, Cécile

“…Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases, and to help the development of drugs…”
Get full text