Search Results - "Ibarra, Beatriz"

Active site center redesign increases protein stability preserving catalysis in thioredoxin by Romero, Maria Luisa, Garcia Seisdedos, Hector, Ibarra‐Molero, Beatriz

“…The stabilization of natural proteins is a long‐standing desired goal in protein engineering. Optimizing the hydrophobicity of the protein core often results…”
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What Do Animal Models Teach Us About Congenital Craniofacial Defects? by Ibarra, Beatriz A, Atit, Radhika

“…The formation of the head and face is a complex process which involves many different signaling cues regulating the migration, differentiation, and…”
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The 14-3-3 Protein Homolog ArtA Regulates Development and Secondary Metabolism in the Opportunistic Plant Pathogen Aspergillus flavus by Ibarra, Beatriz A, Lohmar, Jessica M, Satterlee, Timothy, McDonald, Taylor, Cary, Jeffrey W, Calvo, Ana M

“…The opportunistic plant-pathogenic fungus produces carcinogenic mycotoxins termed aflatoxins (AF). Aflatoxin contamination of agriculturally important crops,…”
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Wnt-Dependent Activation of ERK Mediates Repression of Chondrocyte Fate during Calvarial Development by Ibarra, Beatriz A, Machen, Cody, Atit, Radhika P.

“…Wnt signaling regulates cell fate decisions in diverse contexts during development, and loss of Wnt signaling in the cranial mesenchyme results in a robust and…”
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Psychometric properties of the Postpartum Depression Predictors Inventory–Revised for pregnant women in Mexico by Ibarra-Yruegas, Beatriz, Lara, Ma. Asunción, Navarrete, Laura, Nieto, Lourdes, Kawas Valle, Omar

“…This study assessed the reliability and concurrent validity of the prenatal section of the Postpartum Depression Predictors Inventory–Revised for 250 pregnant…”
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Injection of human neuroblastoma cells into neural crest streams in live zebrafish embryos by Ibarra, Beatriz A., Jiang, Xinghang, Treffy, Randall W., Saxena, Ankur

“…Cancer cell behavior is highly microenvironment dependent, yet we have a limited understanding of malignant cell-microenvironment interactions in vivo. Here,…”
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Transient titin-dependent ventricular defects during development lead to adult atrial arrhythmia and impaired contractility by Jiang, Xinghang, Ly, Olivia T., Chen, Hanna, Zhang, Ziwei, Ibarra, Beatriz A., Pavel, Mahmud A., Brown, Grace E., Sridhar, Arvind, Tofovic, David, Swick, Abigail, Marszalek, Richard, Vanoye, Carlos G., Navales, Fritz, George, Alfred L., Khetani, Salman R., Rehman, Jalees, Gao, Yu, Darbar, Dawood, Saxena, Ankur

“…Developmental causes of the most common arrhythmia, atrial fibrillation (AF), are poorly defined, with compensation potentially masking arrhythmic risk. Here,…”
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Wnt/β-catenin Signaling Pathway Regulates Specific lncRNAs That Impact Dermal Fibroblasts and Skin Fibrosis by Mullin, Nathaniel K, Mallipeddi, Nikhil V, Hamburg-Shields, Emily, Ibarra, Beatriz, Khalil, Ahmad M, Atit, Radhika P

“…Wnt/β-catenin signaling is required for embryonic dermal fibroblast cell fate, and dysregulation of this pathway is sufficient to promote fibrosis in adult…”
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Modern Analysis of Protein Folding by Differential Scanning Calorimetry by Ibarra-Molero, Beatriz, Naganathan, Athi N, Sanchez-Ruiz, Jose M, Muñoz, Victor

“…Differential scanning calorimetry (DSC) is a very powerful tool for investigating protein folding and stability because its experimental output reflects the…”
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The Varieties of Psychosis in Multiple Sclerosis: A Systematic Review of Cases by Camara-Lemarroy, Carlos R, Ibarra-Yruegas, Beatriz E, Rodriguez-Gutierrez, Rene, Berrios-Morales, Idanis, Ionete, Carolina, Riskind, Peter

“…Abstract Objectives Multiple Sclerosis (MS) is known to be associated with a wide range of psychiatric symptoms, particularly with affective disorders…”
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Conservation of Protein Structure over Four Billion Years by Ingles-Prieto, Alvaro, Ibarra-Molero, Beatriz, Delgado-Delgado, Asuncion, Perez-Jimenez, Raul, Fernandez, Julio M., Gaucher, Eric A., Sanchez-Ruiz, Jose M., Gavira, Jose A.

“…Little is known about the evolution of protein structures and the degree of protein structure conservation over planetary time scales. Here, we report the…”
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Engineering protein assemblies with allosteric control via monomer fold-switching by Campos, Luis A., Sharma, Rajendra, Alvira, Sara, Ruiz, Federico M., Ibarra-Molero, Beatriz, Sadqi, Mourad, Alfonso, Carlos, Rivas, Germán, Sanchez-Ruiz, Jose M., Romero Garrido, Antonio, Valpuesta, José M., Muñoz, Victor

“…The macromolecular machines of life use allosteric control to self-assemble, dissociate and change shape in response to signals. Despite enormous interest, the…”
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Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase by Gamiz-Arco, Gloria, Gutierrez-Rus, Luis I., Risso, Valeria A., Ibarra-Molero, Beatriz, Hoshino, Yosuke, Petrović, Dušan, Justicia, Jose, Cuerva, Juan Manuel, Romero-Rivera, Adrian, Seelig, Burckhard, Gavira, Jose A., Kamerlin, Shina C. L., Gaucher, Eric A., Sanchez-Ruiz, Jose M.

“…Glycosidases are phylogenetically widely distributed enzymes that are crucial for the cleavage of glycosidic bonds. Here, we present the exceptional properties…”
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Using Resurrected Ancestral Proviral Proteins to Engineer Virus Resistance by Delgado, Asunción, Arco, Rocio, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.

“…Proviral factors are host proteins hijacked by viruses for processes essential for virus propagation such as cellular entry and replication. Pathogens and…”
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Microbial gut dysbiosis induced by xenobiotics in model organisms and the relevance of experimental criteria: a minireview by Ibarra-Mendoza, Beatriz, Gomez-Gil, Bruno, Betancourt-Lozano, Miguel, Raggi, Luciana, Yáñez-Rivera, Beatriz

“…The gut microbiota is a dynamic ecosystem involved in multiple physiological processes that affect host health. Several factors affect intestinal microbial…”
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Gastrointestinal complications after ischemic stroke by Camara-Lemarroy, Carlos R, Ibarra-Yruegas, Beatriz E, Gongora-Rivera, Fernando

“…Abstract Ischemic stroke is an important cause of morbidity and mortality, and currently the leading cause of adult disability in developed countries. Stroke…”
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Selection for Protein Kinetic Stability Connects Denaturation Temperatures to Organismal Temperatures and Provides Clues to Archaean Life by Romero-Romero, M Luisa, Risso, Valeria A, Martinez-Rodriguez, Sergio, Gaucher, Eric A, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M

“…The relationship between the denaturation temperatures of proteins (Tm values) and the living temperatures of their host organisms (environmental temperatures:…”
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A protocol to study bacteriophage adaptation to new hosts by Luzon-Hidalgo, Raquel, Risso, Valeria A., Delgado, Asuncion, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.

“…A general protocol for the experimental assessment of bacteriophage adaptation to new hosts is described. We use as a model system the lytic phage T7 and an…”
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Large-scale modulation of thermodynamic protein folding barriers linked to electrostatics by Halskau, Øyvind Jr, Perez-Jimenez, Raul, Ibarra-Molero, Beatriz, Underhaug, Jarl, Muñoz, Victor, Martinez, Aurora, Sanchez-Ruiz, Jose M

“…Protein folding barriers, which range from zero to the tens of RT that result in classical two-state kinetics, are primarily determined by protein size and…”
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Probing the mutational interplay between primary and promiscuous protein functions: a computational-experimental approach by Garcia-Seisdedos, Hector, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M

“…Protein promiscuity is of considerable interest due its role in adaptive metabolic plasticity, its fundamental connection with molecular evolution and also…”
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