Search Results - "Ibañez, Luisa"
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Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)“…Background & Aims We performed a genome-wide association study (GWAS) to identify genetic risk factors for drug-induced liver injury (DILI) from licensed drugs…”
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Synergism interaction between genetic polymorphisms in drug metabolizing enzymes and NSAIDs on upper gastrointestinal haemorrhage: a multicenter case-control study
Published in Annals of medicine (Helsinki) (31-12-2022)“…Interindividual genetic variations contribute to differences in patients' response to drugs as well as to the development of certain disorders. Patients who…”
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Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2011)“…Background & Aims Drug-induced liver injury (DILI), especially from antimicrobial agents, is an important cause of serious liver disease…”
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4
Antidepressant use and stroke or mortality risk in the elderly
Published in European journal of neurology (01-02-2022)“…Background and purpose Current evidence on antidepressant‐related stroke or mortality risk is inconsistent. Because the elderly have the highest exposure to…”
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Factors associated with primary nonadherence to newly initiated direct oral anticoagulants in patients with nonvalvular atrial fibrillation
Published in Journal of managed care & specialty pharmacy (01-09-2021)“…Direct oral anticoagulants (DOACs) are widely used for the prevention of stroke in nonvalvular atrial fibrillation (NVAF); however, real-world primary…”
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6
Slepton non-universality in the flavor-effective MSSM
Published in The journal of high energy physics (01-11-2017)“…A bstract Supersymmetric theories supplemented by an underlying flavor-symmetry G f provide a rich playground for model building aimed at explaining the flavor…”
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Association of individual non-steroidal anti-inflammatory drugs and chronic kidney disease: a population-based case control study
Published in PloS one (16-04-2015)“…Non-steroidal anti-inflammatory agents (NSAIDs) are known to be associated with renal damage. No clear evidence exists regarding differential risk of chronic…”
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A multicenter case–control study of the effect of e-nos VNTR polymorphism on upper gastrointestinal hemorrhage in NSAID users
Published in Scientific reports (07-10-2021)“…Bleeding in non-steroidal anti-inflammatory drug (NSAID) users limited their prescription. This first multicenter full case–control study (325 cases and 744…”
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Incidence of direct oral anticoagulant use in patients with nonvalvular atrial fibrillation and characteristics of users in 6 European countries (2008–2015): A cross‐national drug utilization study
Published in British journal of clinical pharmacology (01-11-2019)“…Aims To estimate the incidence of direct oral anticoagulant drug (DOAC) use in patients with nonvalvular atrial fibrillation and to describe user and treatment…”
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Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population
Published in The lancet. Diabetes & endocrinology (01-06-2016)“…Summary Background Drug-induced agranulocytosis is a potentially life-threatening adverse reaction. Genome-wide association studies (GWASs) in ethnic Chinese…”
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Impact of the 2018 revised Pregnancy Prevention Programme by the European Medicines Agency on the use of oral retinoids in females of childbearing age in Denmark, Italy, Netherlands, and Spain: an interrupted time series analysis
Published in Frontiers in pharmacology (17-08-2023)“…Background: In March 2018, the European pregnancy prevention programme for oral retinoids was updated as part of risk minimisation measures (RMM), emphasising…”
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12
Process Optimization of the Flaring Gas for Field Applications
Published in Energies (Basel) (01-10-2022)“…During petroleum industry operations, burning flammable gas components in the flaring stacks is common, normally a symbol for stable production, but flaring…”
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Impact of 2018 EU Risk Minimisation Measures and Revised Pregnancy Prevention Programme on Utilisation and Prescribing Trends of Medicinal Products Containing Valproate: An Interrupted Time Series Study
Published in Drug safety (01-07-2023)“…Introduction Due to established teratogenicity of valproates, the EU risk minimisation measures (RMMs) with a pregnancy prevention programme (PPP) for…”
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A new risk of bias checklist applicable to randomized trials, observational studies and systematic reviews was developed and validated to be used for systematic reviews focusing on drug adverse events
Published in Journal of clinical epidemiology (01-06-2017)“…Abstract Objective To develop and validate an adequate tool to evaluate the risk of bias of randomized controlled trials, observational studies, and systematic…”
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CYP2C9 variants as a risk modifier of NSAID-related gastrointestinal bleeding: a case–control study
Published in Pharmacogenetics and genomics (01-02-2016)“…OBJECTIVEThe aim of this study was to assess whether the CYP2C9*2 and/or *3 variants might modify the risk for NSAID-related upper gastrointestinal bleeding…”
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Epidemiology of aplastic anemia: a prospective multicenter study
Published in Haematologica (Roma) (01-04-2008)“…1 Fundació Institut Català de Farmacologia, Barcelona; 2 Servei de Farmacologia Clínica, Hospital Universitari Vall dHebron, Barcelona; 3 Universitat Autònoma…”
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Utilisation and off-label prescriptions of respiratory drugs in children
Published in PloS one (02-09-2014)“…Respiratory drugs are widely used in children to treat labeled and non-labeled indications but only some data are available quantifying comprehensively…”
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High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis
Published in Frontiers in genetics (21-08-2020)“…Background and Objective: Agranulocytosis is a rare and potentially life-threatening complication of metamizole (dipyrone) intake that is characterized by a…”
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Potential Impact of Benzodiazepine Use on the Rate of Hip Fractures in Five Large European Countries and the United States
Published in Calcified tissue international (01-07-2012)“…Benzodiazepine use increases the risk of falls and has been associated with an increased risk of hip fractures. Our aim was to estimate the possible population…”
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Sulfasalazine‐Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus
Published in Clinical pharmacology and therapeutics (01-05-2018)“…Agranulocytosis is a serious, although rare, adverse reaction to sulfasalazine, which is used to treat inflammatory joint and bowel disease. We performed a…”
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