Search Results - "Ibañez, David P."

Rolling back human pluripotent stem cells to an eight-cell embryo-like stage by Mazid, Md. Abdul, Ward, Carl, Luo, Zhiwei, Liu, Chuanyu, Li, Yunpan, Lai, Yiwei, Wu, Liang, Li, Jinxiu, Jia, Wenqi, Jiang, Yu, Liu, Hao, Fu, Lixin, Yang, Yueli, Ibañez, David P., Lai, Junjian, Wei, Xiaoyu, An, Juan, Guo, Pengcheng, Yuan, Yue, Deng, Qiuting, Wang, Yang, Liu, Ying, Gao, Fei, Wang, Junwen, Zaman, Shahriar, Qin, Baoming, Wu, Guangming, Maxwell, Patrick H., Xu, Xun, Liu, Longqi, Li, Wenjuan, Esteban, Miguel A.

“…After fertilization, the quiescent zygote experiences a burst of genome activation that initiates a short-lived totipotent state. Understanding the process of…”
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NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming by Zhuang, Qiang, Li, Wenjuan, Benda, Christina, Huang, Zhijian, Ahmed, Tanveer, Liu, Ping, Guo, Xiangpeng, Ibañez, David P., Luo, Zhiwei, Zhang, Meng, Abdul, Mazid Md, Yang, Zhongzhou, Yang, Jiayin, Huang, Yinghua, Zhang, Hui, Huang, Dehao, Zhou, Jianguo, Zhong, Xiaofen, Zhu, Xihua, Fu, Xiuling, Fan, Wenxia, Liu, Yulin, Xu, Yan, Ward, Carl, Khan, Muhammad Jadoon, Kanwal, Shahzina, Mirza, Bushra, Tortorella, Micky D., Tse, Hung-Fat, Chen, Jiayu, Qin, Baoming, Bao, Xichen, Gao, Shaorong, Hutchins, Andrew P., Esteban, Miguel A.

“…Somatic cell reprogramming by exogenous factors requires cooperation with transcriptional co-activators and co-repressors to effectively remodel the epigenetic…”
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Generation of two LRRK2 homozygous knockout human induced pluripotent stem cell lines using CRISPR/Cas9 by Chen, Shuhan, Luo, Zhiwei, Ward, Carl, Ibañez, David P., Liu, Hao, Zhong, Xiaofen, Sharma, Narendra K., Qin, Baoming, Fan, Wenxia, Wang, Dongye

“…Mutations in the Leucine rich repeat kinase 2 (LRRK2) gene are found in both familial and sporadic Parkinson's disease (PD), and are also associated with…”
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Generation of an induced pluripotent stem cell line (GIBHi004-A) from a Parkinson’s disease patient with mutant DJ-1/PARK7 (p.L10P) by Li, Yunpan, Ibañez, David P., Fan, Wenxia, Zhao, Ping, Chen, Shuhan, Md. Abdul, Mazid, Jiang, Yu, Fu, Lixin, Luo, Zhiwei, Liu, Zhenhua, Yang, Yueli, Guo, Jifeng, Volpe, Giacomo, Kanwal, Shahzina, Wang, Dongye, Tang, Beisha, Li, Wenjuan

“…Mutations occurring in the gene body of PARK7 (encoding DJ-1/PARK7) cause autosomal recessive early-onset parkinsonism (AREP). These mutations produce a loss…”
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Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N) by Abdul, Mazid Md, Ibañez, David P., Zhao, Ping, Liu, Hao, Zhong, Xiaofen, Li, Yingying, Zhang, Meng, Li, Wenjuan, Li, Yunpan, Ward, Carl, Chen, Shuhan, Wang, Dongye, Qin, Baoming, Esteban, Miguel A., Wang, Xiwei, Fan, Wenxia, Luo, Zhiwei

“…Familial Parkinson's disease (PD) can be caused by deleterious mutations in PINK1 (encoding PINK1) in an autosomal recessive manner. Functional studies suggest…”
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Generation of three induced pluripotent stem cell lines from a Parkinson's disease patient with mutant PARKIN (p. C253Y) by Tariq, Muqddas, Liu, Hao, Ibañez, David P., Li, Yunpan, Chen, Shuhan, Jiang, Mengling, Fan, Wenxia, Zhao, Ping, Luo, Zhiwei, Wang, Dongye, Kanwal, Shahzina

“…Parkinson's disease (PD) is one of the most common neurodegenerative disorders and is characterized by the progressive degeneration of dopaminergic (DA)…”
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Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells by Yang, Jiayin, Wang, Yu, Zhou, Ting, Wong, Lai-Yung, Tian, Xiao-Yu, Hong, Xueyu, Lai, Wing-Hon, Au, Ka-Wing, Wei, Rui, Liu, Yuqing, Cheng, Lai-Hung, Liang, Guichan, Huang, Zhijian, Fan, Wenxia, Zhao, Ping, Wang, Xiwei, Ibañez, David P., Luo, Zhiwei, Li, Yingying, Zhong, Xiaofen, Chen, Shuhan, Wang, Dongye, Li, Li, Lai, Liangxue, Qin, Baoming, Bao, Xichen, Hutchins, Andrew P., Siu, Chung-Wah, Huang, Yu, Esteban, Miguel A., Tse, Hung-Fat

“…Familial hypercholesterolemia (FH) causes elevation of low-density lipoprotein cholesterol (LDL-C) in blood and carries an increased risk of early-onset…”
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A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes by Yang, Jiayin, Wong, Lai-Yung, Tian, Xiao-Yu, Wei, Rui, Lai, Wing-Hon, Au, Ka-Wing, Luo, Zhiwei, Ward, Carl, Ho, Wai-In, Ibañez, David P, Liu, Hao, Bao, Xichen, Qin, Baoming, Huang, Yu, Esteban, Miguel A, Tse, Hung-Fat

“…Familial hypercholesterolemia (FH) is mostly caused by low-density lipoprotein receptor (LDLR) mutations and results in an increased risk of early-onset…”
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Generation of a PARK2 homozygous knockout induced pluripotent stem cell line (GIBHi002-A-1) with two common isoforms abolished by Zhang, Meng, Ibañez, David P., Fan, Wenxia, Liu, Hao, Zhong, Xiaofen, Wang, Xiwei, Li, Yingying, Md. Abdul, Mazid, Li, Wenjuan, Li, Yunpan, Ward, Carl, Chen, Shuhan, Wang, Dongye, Qin, Baoming, Esteban, Miguel A., Zhao, Ping, Luo, Zhiwei

“…Loss of function mutations in PARK2 (encoding PARKIN) cause autosomal recessive Parkinson's disease (PD), which often manifests at a juvenile age. Molecular…”
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Publisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming by Zhuang, Qiang, Li, Wenjuan, Benda, Christina, Huang, Zhijian, Ahmed, Tanveer, Liu, Ping, Guo, Xiangpeng, Ibañez, David P., Luo, Zhiwei, Zhang, Meng, Abdul, Mazid Md, Yang, Zhongzhou, Yang, Jiayin, Huang, Yinghua, Zhang, Hui, Huang, Dehao, Zhou, Jianguo, Zhong, Xiaofen, Zhu, Xihua, Fu, Xiuling, Fan, Wenxia, Liu, Yulin, Xu, Yan, Ward, Carl, Khan, Muhammad Jadoon, Kanwal, Shahzina, Mirza, Bushra, Tortorella, Micky D., Tse, Hung-Fat, Chen, Jiayu, Qin, Baoming, Bao, Xichen, Gao, Shaorong, Hutchins, Andrew P., Esteban, Miguel A.

“…In the version of this Article originally published, in Fig. 2c, the ‘+’ sign and ‘OSKM’ were superimposed in the label ‘+OSKM’. In Fig. 4e, in the labels, all…”
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Solving the puzzle of Parkinson's disease using induced pluripotent stem cells by Zhao, Ping, Luo, Zhiwei, Tian, Weihua, Yang, Jiayin, Ibáñez, David P, Huang, Zhijian, Tortorella, Micky D, Esteban, Miguel A, Fan, Wenxia

“…The prevalence and incidence of Parkinson's disease (PD) is increasing due to a prolonged life expectancy. This highlights the need for a better mechanistic…”
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β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus by Zhang, Meng, Lai, Yiwei, Krupalnik, Vladislav, Guo, Pengcheng, Guo, Xiangpeng, Zhou, Jianguo, Xu, Yan, Yu, Zhijun, Liu, Longqi, Jiang, Ao, Li, Wenjuan, Abdul, Mazid Md, Ma, Gang, Li, Na, Fu, Xiuling, Lv, Yuan, Jiang, Mengling, Tariq, Muqddas, Kanwal, Shahzina, Liu, Hao, Xu, Xueting, Zhang, Hui, Huang, Yinghua, Wang, Lulu, Chen, Shuhan, Babarinde, Isaac A, Luo, Zhiwei, Wang, Dongye, Zhou, Tiantian, Ward, Carl, He, Minghui, Ibañez, David P, Li, Yunpan, Zhou, Jiajian, Yuan, Jie, Feng, Yayan, Arumugam, Karthik, Di Vicino, Umberto, Bao, Xichen, Wu, Guangming, Schambach, Axel, Wang, Huating, Sun, Hao, Gao, Fei, Qin, Baoming, Hutchins, Andrew P, Doble, Bradley W, Hartmann, Christine, Cosma, Maria Pia, Qin, Yan, Xu, Guo-Liang, Chen, Runsheng, Volpe, Giacomo, Chen, Liang, Hanna, Jacob H, Esteban, Miguel A

“…Mouse embryonic stem cells cultured with MEK (mitogen-activated protein kinase kinase) and GSK3 (glycogen synthase kinase 3) inhibitors (2i) more closely…”
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A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes by Yang, Jiayin, Wong, Lai-Yung, Tian, Xiao-Yu, Wei, Rui, Lai, Wing-Hon, Au, Ka-Wing, Luo, Zhiwei, Ward, Carl, Ho, Wai-In, Ibañez, David P., Liu, Hao, Bao, Xichen, Qin, Baoming, Huang, Yu, Esteban, Miguel A., Tse, Hung-Fat

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