Search Results - "Ibañez, Andrés E."
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Spatial and sex differences in mercury contamination of skuas in the Southern Ocean
Published in Environmental pollution (1987) (15-03-2022)“…Antarctic marine ecosystems are often considered to be pristine environments, yet wildlife in the polar regions may still be exposed to high levels of…”
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An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice
Published in PloS one (14-01-2011)“…As Brucella infections occur mainly through mucosal surfaces, the development of mucosal administered vaccines could be radical for the control of brucellosis…”
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3
Migration strategies of skuas in the southwest Atlantic Ocean revealed by stable isotopes
Published in Marine biology (2024)“…Stable isotope ratios of carbon (δ 13 C) and nitrogen (δ 15 N) were measured in feathers to compare the non-breeding distributions and habitat use of adult…”
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Brucella cyclic β-1,2-glucan plays a critical role in the induction of splenomegaly in mice
Published in PloS one (01-07-2014)“…Brucella, the etiological agent of animal and human brucellosis, is a bacterium with the capacity to modulate the inflammatory response. Cyclic β-1,2-glucan…”
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Phenotypic plasticity in Pygoscelis adeliae physiology and immunity under anthropogenic pressure: a proteomic and biochemical scenario
Published in Marine biology (01-05-2021)“…The capacity of seabirds to shape their physiological and immune phenotypes may often be constrained by the ecological context. While phenotypic plasticity in…”
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Novel Role for Animal Innate Immune Molecules: Enterotoxic Activity of a Snail Egg MACPF-Toxin
Published in Frontiers in immunology (13-03-2020)“…Gastropod Molluscs rely exclusively on the innate immune system to protect from pathogens, defending their embryos through maternally transferred effectors. In…”
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Evaluation of the efficacy of outer membrane protein 31 vaccine formulations for protection against Brucella canis in BALB/c mice
Published in Clinical and vaccine immunology (01-12-2014)“…Canine brucellosis is an infectious disease caused by the Gram-negative bacterium Brucella canis. Unlike conventional control programs for other species of the…”
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A Brucella spp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+ T Cell Responses
Published in The Journal of immunology (1950) (15-05-2016)“…In this study, we demonstrate that the unlipidated (U) outer membrane protein (Omp) 19 from Brucella spp. is a competitive inhibitor of human cathepsin L…”
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Brucella abortus Omp19 recombinant protein subcutaneously co-delivered with an antigen enhances antigen-specific T helper 1 memory responses and induces protection against parasite challenge
Published in Vaccine (20-01-2016)“…Abstract The discovery of effective adjuvants for many vaccines especially those with limited commercial appeal, such as vaccines to poverty-related diseases,…”
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Hematology, Biochemistry and Serum Protein Analyses of Antarctic and non-Antarctic Skuas
Published in Waterbirds (De Leon Springs, Fla.) (01-06-2015)“…Determination of hematological and biochemical parameters provides important data to assess the physiological condition in wild birds. Therefore, to carry out…”
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The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis
Published in The Journal of immunology (1950) (01-05-2010)“…Knowing the inherent stimulatory properties of the lipid moiety of bacterial lipoproteins, we first hypothesized that Brucella abortus outer membrane protein…”
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12
U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice
Published in Frontiers in immunology (17-02-2017)“…Most pathogens infect through mucosal surfaces, and parenteral immunization typically fails to induce effective immune responses at these sites. Development of…”
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13
Unlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteins
Published in PloS one (05-07-2013)“…The discovery of novel mucosal adjuvants will help to develop new formulations to control infectious and allergic diseases. In this work we demonstrate that…”
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14
Haematological values of three Antarctic penguins: gentoo (Pygoscelis papua), Adélie (P. adeliae) and chinstrap (P. antarcticus)
Published in Polar Research (01-01-2015)“…It is established that haematological and biochemical parameters provide important data to assess the physiological condition and health status of wild birds…”
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Journal Article Book Review -
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Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases
Published in Journal of neuroinflammation (12-04-2013)“…Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. We have recently…”
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Deleterious effects of mercury contamination on immunocompetence, liver function and egg volume in an antarctic seabird
Published in Chemosphere (Oxford) (01-01-2024)“…Mercury (Hg) is a globally important pollutant that can negatively impact metabolic, endocrine and immune systems of marine biota. Seabirds are long-lived…”
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Brucella abortus inhibits IFN-γ-induced FcγRI expression and FcγRI-restricted phagocytosis via toll-like receptor 2 on human monocytes/macrophages
Published in Microbes and infection (01-03-2011)“…The strategies that allow Brucella abortus to persist for years inside macrophages subverting host immune responses are not completely understood. Immunity…”
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Brucella abortus induces TNF-[alpha]-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases
Published in Journal of neuroinflammation (01-01-2013)“…Doc number: 47 Abstract Background: Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called…”
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Brucella abortus induces apoptosis of human T lymphocytes
Published in Microbes and infection (01-07-2012)“…Immune evasion is essential for Brucella abortus to survive in the face of robust adaptive CD4+ T cell response. We have previously demonstrated that B…”
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Variation in blood mercury concentrations in brown skuas (Stercorarius antarcticus) is related to trophic ecology but not breeding success or adult body condition
Published in Marine pollution bulletin (01-08-2022)“…Mercury is a pervasive environmental contaminant that can negatively impact seabirds. Here, we measure total mercury (THg) concentrations in red blood cells…”
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