Search Results - "Ianeselli, Alan"

Non-equilibrium conditions inside rock pores drive fission, maintenance and selection of coacervate protocells by Ianeselli, Alan, Tetiker, Damla, Stein, Julian, Kühnlein, Alexandra, Mast, Christof B., Braun, Dieter, Dora Tang, T.-Y.

“…Key requirements for the first cells on Earth include the ability to compartmentalize and evolve. Compartmentalization spatially localizes biomolecules from a…”
Get full text

Kinetic Microscale Thermophoresis for Simultaneous Measurement of Binding Affinity and Kinetics by Stein, Julian A. C., Ianeselli, Alan, Braun, Dieter

“…Microscale thermophoresis (MST) is a versatile technique to measure binding affinities of binder–ligand systems, based on the directional movement of molecules…”
Get full text

Periodic Melting of Oligonucleotides by Oscillating Salt Concentrations Triggered by Microscale Water Cycles Inside Heated Rock Pores by Ianeselli, Alan, Mast, Christof B., Braun, Dieter

“…To understand the emergence of life, a better understanding of the physical chemistry of primordial non‐equilibrium conditions is essential. Significant salt…”
Get full text

Water cycles in a Hadean CO2 atmosphere drive the evolution of long DNA by Ianeselli, Alan, Atienza, Miguel, Kudella, Patrick W., Gerland, Ulrich, Mast, Christof B., Braun, Dieter

“…Dew is a common form of water that deposits from saturated air on colder surfaces. Although presumably common on primordial Earth, its potential involvement in…”
Get full text

A Complete Analysis Pipeline for the Processing, Alignment and Quantification of HPLC–UV Wine Chromatograms by Ianeselli, Alan, Longo, Edoardo, Poggesi, Simone, Montali, Marco, Boselli, Emanuele

“…Elucidating the chemistry of wine would help defining its quality, chemical and sensory characteristics and optimise the wine-making processes…”
Get full text

Heated gas bubbles enrich, crystallize, dry, phosphorylate and encapsulate prebiotic molecules by Morasch, Matthias, Liu, Jonathan, Dirscherl, Christina F., Ianeselli, Alan, Kühnlein, Alexandra, Le Vay, Kristian, Schwintek, Philipp, Islam, Saidul, Corpinot, Mérina K., Scheu, Bettina, Dingwell, Donald B., Schwille, Petra, Mutschler, Hannes, Powner, Matthew W., Mast, Christof B., Braun, Dieter

“…Non-equilibrium conditions must have been crucial for the assembly of the first informational polymers of early life, by supporting their formation and…”
Get full text

Pharmacological inactivation of the prion protein by targeting a folding intermediate by Spagnolli, Giovanni, Massignan, Tania, Astolfi, Andrea, Biggi, Silvia, Rigoli, Marta, Brunelli, Paolo, Libergoli, Michela, Ianeselli, Alan, Orioli, Simone, Boldrini, Alberto, Terruzzi, Luca, Bonaldo, Valerio, Maietta, Giulia, Lorenzo, Nuria L., Fernandez, Leticia C., Codeseira, Yaiza B., Tosatto, Laura, Linsenmeier, Luise, Vignoli, Beatrice, Petris, Gianluca, Gasparotto, Dino, Pennuto, Maria, Guella, Graziano, Canossa, Marco, Altmeppen, Hermann C., Lolli, Graziano, Biressi, Stefano, Pastor, Manuel M., Requena, Jesús R., Mancini, Ines, Barreca, Maria L., Faccioli, Pietro, Biasini, Emiliano

“…Recent computational advancements in the simulation of biochemical processes allow investigating the mechanisms involved in protein regulation with realistic…”
Get full text

Development of a universal endogenous qPCR control for eukaryotic DNA samples by Mittelberger, Cecilia, Obkircher, Lisa, Oberkofler, Vicky, Ianeselli, Alan, Kerschbamer, Christine, Gallmetzer, Andreas, Reyes-Dominguez, Yazmid, Letschka, Thomas, Janik, Katrin

“…Phytoplasma are obligate intracellular plant-pathogenic bacteria that infect a broad range of plant species and are transmitted by different insect species…”
Get full text

Atomic Detail of Protein Folding Revealed by an Ab Initio Reappraisal of Circular Dichroism by Ianeselli, Alan, Orioli, Simone, Spagnolli, Giovanni, Faccioli, Pietro, Cupellini, Lorenzo, Jurinovich, Sandro, Mennucci, Benedetta

“…Circular dichroism (CD) is known to be an excellent tool for the determination of protein secondary structure due to fingerprint signatures of α and β domains…”
Get full text

A heated rock crack captures and polymerizes primordial DNA and RNA by Dirscherl, Christina F, Ianeselli, Alan, Tetiker, Damla, Matreux, Thomas, Queener, Robbin M, Mast, Christof B, Braun, Dieter

“…Life is based on informational polymers such as DNA or RNA. For their polymerization, high concentrations of complex monomer building blocks are required…”
Get more information

Physical non-equilibria for prebiotic nucleic acid chemistry by Ianeselli, Alan, Salditt, Annalena, Mast, Christof, Ercolano, Barbara, Kufner, Corinna L., Scheu, Bettina, Braun, Dieter

“…The prebiotic replication of DNA and RNA is a complex interplay between chemistry and the environment. Factors that have direct and indirect effects on…”
Get full text

All-Atom Simulations Reveal How Single-Point Mutations Promote Serpin Misfolding by Wang, Fang, Orioli, Simone, Ianeselli, Alan, Spagnolli, Giovanni, a Beccara, Silvio, Gershenson, Anne, Faccioli, Pietro, Wintrode, Patrick L.

“…Protein misfolding is implicated in many diseases, including serpinopathies. For the canonical inhibitory serpin α1-antitrypsin, mutations can result in…”
Get full text

Periodic Melting of Oligonucleotides by Oscillating Salt Concentrations Triggered by Microscale Water Cycles Inside Heated Rock Pores by Ianeselli, Alan, Mast, Christof B., Braun, Dieter

“…To understand the emergence of life, a better understanding of the physical chemistry of primordial non‐equilibrium conditions is essential. Significant salt…”
Get full text

Kinetic Microscale Thermophoresis for Simultaneous Measurement of Binding Affinity and Kinetics by Stein, Julian A. C., Ianeselli, Alan, Braun, Dieter

“…Microscale thermophoresis (MST) is a versatile technique to measure binding affinities of binder–ligand systems, based on the directional movement of molecules…”
Get full text

Heated gas bubbles enrich, crystallize, dry, phosphorylate and encapsulate prebiotic molecules by Morasch, Matthias, Liu, Jonathan, Dirscherl, Christina F, Ianeselli, Alan, Kühnlein, Alexandra, Vay, Kristian Le, Schwintek, Philipp, Islam, Saidul, Corpinot, Mérina K, Scheu, Bettina, Dingwell, Donald B, Schwille, Petra, Mutschler, Hannes, Powner, Matthew W, Mast, Christof B, Braun, Dieter

“…Nature Chemistry volume 11, pages 779-788, year 2019 Non-equilibrium conditions must have been crucial for the assembly of the first informational polymers of…”
Get full text

All-atom simulations reveal how single point mutations promote serpin misfolding by Wang, Fang, Orioli, Simone, Ianeselli, Alan, Spagnolli, Giovanni, Beccara, Silvio a, Gershenson, Anne, Faccioli, Pietro, Wintrode, Patrick L

“…Biophys. J. 114, 2083 (2018) Protein misfolding is implicated in many diseases, including the serpinopathies. For the canonical inhibitory serpin…”
Get full text