Search Results - "Ian Harris, R."

RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells by Inana, George, Murat, Christopher, An, Weijun, Yao, Xiang, Harris, Ian R, Cao, Jing

“…Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly characterized by retinal pigment epithelium (RPE) degeneration with…”
Get full text

Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins by Koh, Sehwon, Kim, Namsoo, Yin, Henry H, Harris, Ian R, Dejneka, Nadine S, Eroglu, Cagla

“…Cell therapy demonstrates great potential for the treatment of neurological disorders. Human umbilical tissue-derived cells (hUTCs) were previously shown to…”
Get full text

Immunogenicity of umbilical cord tissue–derived cells by Cho, Patricia S., Messina, Darin J., Hirsh, Erica L., Chi, Nina, Goldman, Stephanie N., Lo, Diana P., Harris, Ian R., Popma, Sicco H., Sachs, David H., Huang, Christene A.

“…Umbilical cord tissue provides a unique source of cells with potential for tissue repair. Umbilical cord tissue–derived cells (UTCs) are MHC class I (MHCI)…”
Get full text

A simulation method for the macro-meteorological wind speed and the implications for extreme value analysis by Ian Harris, R.

“…This paper provides a contribution to the testing of existing methods of analysis of extreme wind speeds and to the development of better alternatives. A…”
Get full text

Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity by Koh, Sehwon, Chen, William J, Dejneka, Nadine S, Harris, Ian R, Lu, Bin, Girman, Sergey, Saylor, Joshua, Wang, Shaomei, Eroglu, Cagla

“…Human umbilical tissue-derived cells (hUTC or palucorcel) are currently under clinical investigation for the treatment of geographic atrophy, a late stage of…”
Get full text

Human umbilical tissue‐derived cells rescue retinal pigment epithelium dysfunction in retinal degeneration by Cao, Jing, Murat, Christopher, An, Weijun, Yao, Xiang, Lee, John, Santulli‐Marotto, Sandra, Harris, Ian R., Inana, George

“…Retinal pigment epithelium (RPE) cells perform many functions crucial for retinal preservation and vision. RPE cell dysfunction results in various retinal…”
Get full text

Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease by Lund, Raymond D, Wang, Shaomei, Lu, Bin, Girman, Sergej, Holmes, Toby, Sauvé, Yves, Messina, Darin J, Harris, Ian R, Kihm, Anthony J, Harmon, Alexander M, Chin, Feng-Yi, Gosiewska, Anna, Mistry, Sanjay K

“…Progressive photoreceptor degeneration resulting from genetic and other factors is a leading and largely untreatable cause of blindness worldwide. The object…”
Get full text

XIMIS, a penultimate extreme value method suitable for all types of wind climate by Harris, R. Ian

“…This paper introduces XIMIS, an extended version of the existing IMIS method. The new method is penultimate in that it does not rely on asymptotic results,…”
Get full text

UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes by Farrell, A M, Uchida, Y, Nagiec, M M, Harris, I R, Dickson, R C, Elias, P M, Holleran, W M

“…The enzyme serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the first committed and rate-limiting step in sphingolipid synthesis, is…”
Get full text

Human Umbilical Tissue-Derived Cells Secrete Soluble VEGFR1 and Inhibit Choroidal Neovascularization by Cao, Jing, Yang, Rong, Smith, Taylor E., Evans, Stephanie, McCollum, Gary W., Pomerantz, Steven C., Petley, Theodore, Harris, Ian R., Penn, John S.

“…Exudative age-related macular degeneration (AMD), characterized by choroidal neovascularization (CNV), is the leading cause of irreversible blindness in…”
Get full text

The minimum L2 distance estimator for Poisson mixture models by HARRIS, Ian R, SHUYI SHEN

Get full text

Parallel regulation of sterol regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine epidermis by Harris, I R, Farrell, A M, Holleran, W M, Jackson, S, Grunfeld, C, Elias, P M, Feingold, K R

“…After permeability barrier perturbation there is an increase in the mRNA levels for key enzymes necessary for lipid synthesis in the epidermis. The…”
Get full text

Exact and general FT1 penultimate distributions of extreme wind speeds drawn from tail-equivalent Weibull parents by Cook, Nicholas J., Harris, R.Ian

“…We present a contribution to the current debate on methodologies for assessing extreme wind speeds. We review long-established extreme theory in the light of…”
Get full text

Postscript to “Exact and general FT1 penultimate distributions of extreme wind speeds drawn from tail-equivalent Weibull parents” by Cook, Nicholas J., Harris, R. Ian

“…We present a further contribution to the current debate on methodologies for assessing extreme wind speeds, adding further insights to a recent paper which…”
Get full text

Regulation of HMG-CoA Synthase and HMG-CoA Reductase by Insulin and Epidermal Growth Factor in HaCaT Keratinocytes by Harris, Ian R., Höppner, Hendrik, Siefken, Wilfried, Wittern, Klaus-Peter, Farrell, Angela M.

“…Synthesis of cholesterol, via the isoprenoid/mevalonate pathway, is required for keratinocyte growth and differentiation, and maintenance of the stratum…”
Get full text

A comparison of related density‐based minimum divergence estimators by Jones, M. C., Hjort, Nils Lid, Harris, Ian R., Basu, Ayanendranath

“…This paper compares the minimum divergence estimator of Basu et al. (1998) to a competing minimum divergence estimator which turns out to be equivalent to a…”
Get full text

A Family of Sequences which Converge to the Euler-Mascheroni Constant by Harris, Ian R.

“…This article considers the Euler-Mascheroni constant (γ) as the limit of a continuous function. Graphs of the function shed light on some familiar…”
Get full text

Extreme wind speeds in mixed climates revisited by Cook, Nicholas J., Ian Harris, R., Whiting, Richard

“…The methodology for the analysis of extreme wind speeds in mixed climates originally proposed in 1978 by Gomes and Vickery is updated to take advantage of…”
Get full text

Restoring function and aesthetics in a patient previously treated for amelogenesis imperfecta by Al-Salehi, Samira K, Dooley, Kevin, Harris, Ian R

“…A 26-year-old male patient presented with generalised gingival recession related to the margins of crowns fitted between the ages of 12 and 15 years. The…”
Get more information

The Level Crossing Method applied to mean wind speeds from “mixed” climates by Harris, R. Ian

“…•Re-examination of theory of original Level Crossing Method.•Confirmation of errors by checking against synthetic data.•New theoretical result for level…”
Get full text