Search Results - "Ian, Ellis"

Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update by Wolff, Antonio C, Hammond, M Elizabeth Hale, Allison, Kimberly H, Harvey, Brittany E, Mangu, Pamela B, Bartlett, John M S, Bilous, Michael, Ellis, Ian O, Fitzgibbons, Patrick, Hanna, Wedad, Jenkins, Robert B, Press, Michael F, Spears, Patricia A, Vance, Gail H, Viale, Giuseppe, McShane, Lisa M, Dowsett, Mitchell

“…Purpose To update key recommendations of the American Society of Clinical Oncology/College of American Pathologists human epidermal growth factor receptor 2…”
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Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update by Wolff, Antonio C, Hammond, M Elizabeth Hale, Allison, Kimberly H, Harvey, Brittany E, Mangu, Pamela B, Bartlett, John M S, Bilous, Michael, Ellis, Ian O, Fitzgibbons, Patrick, Hanna, Wedad, Jenkins, Robert B, Press, Michael F, Spears, Patricia A, Vance, Gail H, Viale, Giuseppe, McShane, Lisa M, Dowsett, Mitchell

“…To update key recommendations of the American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) human epidermal growth factor receptor…”
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Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups by Rueda, Oscar M., Sammut, Stephen-John, Seoane, Jose A., Chin, Suet-Feung, Caswell-Jin, Jennifer L., Callari, Maurizio, Batra, Rajbir, Pereira, Bernard, Bruna, Alejandra, Ali, H. Raza, Provenzano, Elena, Liu, Bin, Parisien, Michelle, Gillett, Cheryl, McKinney, Steven, Green, Andrew R., Murphy, Leigh, Purushotham, Arnie, Ellis, Ian O., Pharoah, Paul D., Rueda, Cristina, Aparicio, Samuel, Caldas, Carlos, Curtis, Christina

“…The rates and routes of lethal systemic spread in breast cancer are poorly understood owing to a lack of molecularly characterized patient cohorts with…”
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Myoepithelial and epithelial-myoepithelial, mesenchymal and fibroepithelial breast lesions: updates from the WHO Classification of Tumours of the Breast 2012 by Tan, Puay Hoon, Ellis, Ian O

“…In the 4th edition of the WHO Classification of Tumours of the Breast, myoepithelial lesions are retitled myoepithelial and epithelial-myoepithelial lesions in…”
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An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer by Teschendorff, Andrew E, Miremadi, Ahmad, Pinder, Sarah E, Ellis, Ian O, Caldas, Carlos

“…Estrogen receptor (ER)-negative breast cancer specimens are predominantly of high grade, have frequent p53 mutations, and are broadly divided into…”
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Breast tumor microenvironment structures are associated with genomic features and clinical outcome by Danenberg, Esther, Bardwell, Helen, Zanotelli, Vito R. T., Provenzano, Elena, Chin, Suet-Feung, Rueda, Oscar M., Green, Andrew, Rakha, Emad, Aparicio, Samuel, Ellis, Ian O., Bodenmiller, Bernd, Caldas, Carlos, Ali, H. Raza

“…The functions of the tumor microenvironment (TME) are orchestrated by precise spatial organization of specialized cells, yet little is known about the…”
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Effect of mammographic screening from age 40 years on breast cancer mortality (UK Age trial): final results of a randomised, controlled trial by Duffy, Stephen W, Vulkan, Daniel, Cuckle, Howard, Parmar, Dharmishta, Sheikh, Shama, Smith, Robert A, Evans, Andrew, Blyuss, Oleg, Johns, Louise, Ellis, Ian O, Myles, Jonathan, Sasieni, Peter D, Moss, Sue M

“…The appropriate age range for breast cancer screening remains a matter of debate. We aimed to estimate the effect of mammographic screening at ages 40–48 years…”
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Basal-Like Breast Cancer: A Critical Review by RAKHA, Emad A, REIS-FILHO, Jorge S, ELLIS, Ian O

“…Recent gene expression profiling of breast cancer has identified specific subtypes with clinical, biologic, and therapeutic implications. The basal-like group…”
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UK recommendations for HER2 assessment in breast cancer: an update by Rakha, Emad A, Tan, Puay Hoon, Quinn, Cecily, Provenzano, Elena, Shaaban, Abeer M, Deb, Rahul, Callagy, Grace, Starczynski, Jane, Lee, Andrew H S, Ellis, 1, Ian O, Pinder, Sarah E

“…The last UK breast cancer (BC) human epidermal growth factor receptor 2 (HER2) testing guideline recommendations were published in 2015. Since then, new data…”
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Breast cancer prognostic classification in the molecular era: the role of histological grade by Rakha, Emad A, Reis-Filho, Jorge S, Baehner, Frederick, Dabbs, David J, Decker, Thomas, Eusebi, Vincenzo, Fox, Stephen B, Ichihara, Shu, Jacquemier, Jocelyne, Lakhani, Sunil R, Palacios, José, Richardson, Andrea L, Schnitt, Stuart J, Schmitt, Fernando C, Tan, Puay-Hoon, Tse, Gary M, Badve, Sunil, Ellis, Ian O

“…Breast cancer is a heterogeneous disease with varied morphological appearances, molecular features, behavior, and response to therapy. Current routine clinical…”
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Prognostic Value of a Combined Estrogen Receptor, Progesterone Receptor, Ki-67, and Human Epidermal Growth Factor Receptor 2 Immunohistochemical Score and Comparison With the Genomic Health Recurrence Score in Early Breast Cancer by CUZICK, Jack, DOWSETT, Mitch, HOWELL, Anthony, BUZDAR, Aman U, FORBES, John F, PINEDA, Silvia, WALE, Christopher, SALTER, Janine, QUINN, Emma, ZABAGLO, Lila, MALLON, Elizabeth, GREEN, Andrew R, ELLIS, Ian O

“…We recently reported that the mRNA-based, 21-gene Genomic Health recurrence score (GHI-RS) provided additional prognostic information regarding distant…”
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Intraductal proliferative lesions of the breast: morphology, associated risk and molecular biology by Ellis, Ian O

“…The main objectives of this review are (1) to review the histological criteria and terminology for usual ductal hyperplasia, atypical ductal hyperplasia, flat…”
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Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival by Joseph, Chitra, Alsaleem, Mansour, Orah, Nnamdi, Narasimha, Pavan L., Miligy, Islam M., Kurozumi, Sasagu, Ellis, Ian O., Mongan, Nigel P., Green, Andrew R., Rakha, Emad A.

“…Purpose MMP9 is a matricellular protein associated with extracellular matrix (ECM) remodelling, that promotes tumour progression, and modulates the activity of…”
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Tumor-Infiltrating CD8+ Lymphocytes Predict Clinical Outcome in Breast Cancer by MAHMOUD, Sahar M. A, CLAIRE PAISH, Emma, POWE, Desmond G, MACMILLAN, R. Douglas, GRAINGE, Matthew J, LEE, Andrew H. S, ELLIS, Ian O, GREEN, Andrew R

“…Breast carcinomas are often infiltrated by inflammatory cells, particularly macrophages and T lymphocytes, but the significance of these cells remains unclear…”
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Adenomyoepithelioma of the breast: a proposal for classification by Rakha, Emad, Tan, Puay Hoon, Ellis, Ian, Quinn, Cecily

“…Breast lesions with a prominent myoepithelial cell component constitute a heterogeneous group of benign and malignant neoplastic proliferations. These lesions…”
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Perineural invasion in oral squamous cell carcinoma: Incidence, prognostic impact and molecular insight by Alkhadar, Huda, Macluskey, Michaelina, White, Sharon, Ellis, Ian

“…Background The objective of this study was to characterise the incidence and prognostic correlation of perineural invasion (PNI) in oral squamous cell…”
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The Spectrum of Triple-Negative Breast Disease: High- and Low-Grade Lesions by Geyer, Felipe C, Pareja, Fresia, Weigelt, Britta, Rakha, Emad, Ellis, Ian O, Schnitt, Stuart J, Reis-Filho, Jorge S

“…Triple-negative breast cancer is viewed clinically as an aggressive subgroup of breast cancer. In fact, most triple-negative breast cancers are poor-prognosis…”
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The Migration and Invasion of Oral Squamous Carcinoma Cells: Matrix, Growth Factor and Signalling Involvement by Ellis, Ian R.

“…The link between the migration of cancer cells and the spread of cancers has been established for many years [...]…”
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Effect of Mifepristone on Migration and Proliferation of Oral Cancer Cells by Iftikhar, Anem, Shepherd, Simon, Jones, Sarah, Ellis, Ian

“…Glucocorticoid receptor (GR) overexpression has been linked to increased tumour aggressiveness and treatment resistance. GR antagonists have been shown to…”
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Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival by Pu, Xuan, Storr, Sarah J., Zhang, Yimin, Rakha, Emad A., Green, Andrew R., Ellis, Ian O., Martin, Stewart G.

“…Impaired apoptosis is one of the hallmarks of cancer. Caspase-3 and -8 are key regulators of the apoptotic response and have been shown to interact with the…”
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