Search Results - "Iadarola, M. J."

Salivary anti-Ro60 and anti-Ro52 Antibody Profiles to Diagnose Sjögren’s Syndrome by Ching, K.H., Burbelo, P.D., Gonzalez-Begne, M., Roberts, M.E.P., Coca, A., Sanz, I., Iadarola, M.J.

“…Simple and non-invasive saliva-based diagnostics may be useful for the identification, understanding, and monitoring of autoimmune and infectious diseases…”
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Monocyte chemoattractant protein-1 in the choroid plexus: A potential link between vascular pro-inflammatory mediators and the CNS during peripheral tissue inflammation by Mitchell, K, Yang, H.-Y.T, Berk, J.D, Tran, J.H, Iadarola, M.J

“…Abstract During peripheral tissue inflammation, inflammatory processes in the CNS can be initiated by blood-borne pro-inflammatory mediators. The choroid…”
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New technologies for studying the complexity of oral diseases by Burbelo, PD, Bayat, A, Lebovitz, EE, Iadarola, MJ

“…Oral Diseases (2012) 18, 121–126 Several new technologies are providing useful diagnostic tools and new information related to the pathogenesis of certain oral…”
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Pain Intensity Processing Within the Human Brain: A Bilateral, Distributed Mechanism by Coghill, Robert C, Sang, Christine N, Maisog, Jose Ma, Iadarola, Michael J

“…  1 Pain and Neurosensory Mechanisms Branch, National Institutes of Dental Research and   2 Laboratory of Brain and Cognition, National Institute of Mental…”
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Activation of spinal neuropeptide FF and the neuropeptide FF receptor 2 during inflammatory hyperalgesia in rats by YANG, H.-Y. T, IADAROLA, M. J

“…Several lines of evidence suggest that neuropeptide FF (NPFF) is involved in nociception and in the modulation of opioid-mediated analgesia. Following the…”
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Neural activation during acute capsaicin-evoked pain and allodynia assessed with PET by IADAROLA, M. J, BERMAN, K. F, ZEFFIRO, T. A, BYAS-SMITH, M. G, GRACELY, R. H, MAX, M. B, BENNETT, G. J

“…The PET H2 15O-bolus method was used to image regional brain activity in normal human subjects during intense pain induced by intradermal injection of…”
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Cocaine induces striatal c-fos-immunoreactive proteins via dopaminergic D1 receptors by YOUNG, S. T, PORRINO, L. J, IADAROLA, M. J

“…The protooncogene c-fos produces a phosphoprotein, Fos, which regulates gene transcription processes. In neuronal systems, Fos has been proposed to couple…”
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Genetic predictors for acute experimental cold and heat pain sensitivity in humans by Kim, H, Mittal, D P, Iadarola, M J, Dionne, R A

“…Background: The genetic contribution to pain sensitivity underlies a complex composite of parallel pain pathways, multiple mechanisms, and diverse…”
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Long-term pain relief in canine osteoarthritis by a single intra-articular injection of resiniferatoxin, a potent TRPV1 agonist by Iadarola, Michael J., Sapio, Matthew R., Raithel, Stephen J., Mannes, Andrew J., Brown, Dorothy Cimino

“…The translational potential of analgesic approaches emerging from basic research can be augmented by client-owned dog trials. We report on a peripheral…”
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Adenoviral gene transfer to spinal cord neurons: intrathecal vs. intraparenchymal administration by Mannes, A.J., Caudle, R.M., O'Connell, B.C., Iadarola, M.J.

“…The spinal cord is the site of many chronic, debilitating, neurological disorders that may be amenable to gene therapy. The present study, using quantitative…”
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A paracrine paradigm for in vivo gene therapy in the central nervous system: treatment of chronic pain by Finegold, A A, Mannes, A J, Iadarola, M J

“…A limitation of current gene therapy efforts aimed at central nervous system disorders concerns distribution of vectors on direct injection into neural tissue…”
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Spinal cord genes enriched in rat dorsal horn and induced by noxious stimulation identified by subtraction cloning and differential hybridization by Yang, H.-Y.T, Wilkening, S, Iadarola, M.J

“…Persistent nociceptive input increases neuronal excitability and induces a program of gene expression in the dorsal spinal cord. The alteration in gene…”
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A kinetic analysis of substance P trafficking by Sarntinoranont, M, Iadarola, M J, Morrison, P F

“…The potential for administering substance P (SP) nocitoxins for the treatment of chronic pain has been identified. To characterize treatment protocols for the…”
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Excitatory Amino Acid Recognition Sites Coupled with Inositol Phospholipid Metabolism: Developmental Changes and Interaction with α 1-adrenoceptors by Nicoletti, F., Iadarola, M. J., Wroblewski, J. T., Costa, E.

“…Glutamate, aspartate, ibotenate, and quisqualate activate inositol phospholipid hydrolysis in hippocampal slices prepared from brains of 6- to 8-day-old rats…”
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Recombinant proteins attached to a nickel-NTA column: use in affinity purification of antibodies by Gu, J, Stephenson, C G, Iadarola, M J

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In situ Hybridization Histochemistry and Immunocytochemistry Reveal an Increase in Spinal Dynorphin Biosynthesis in a Rat Model of Peripheral Inflammation and Hyperalgesia by Ruda, M. A., Iadarola, M. J., Cohen, L. V., Young, W. S.

“…Dynorphin, an opioid peptide, is thought to play an important role in the modulation of nociceptive neural circuits at the level of the spinal cord. In a model…”
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Epidural resiniferatoxin induced prolonged regional analgesia to pain by Szabo, Tamas, Olah, Zoltan, Iadarola, Michael J, Blumberg, Peter M

“…Adequate treatment of cancer pain remains a significant clinical problem. To reduce side effects of treatment, intrathecal and epidural routes of…”
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Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: possible involvement of noradrenergic mechanisms by Hylden, J L, Thomas, D A, Iadarola, M J, Nahin, R L, Dubner, R

“…We have examined the spinal analgesic activity of opioid agonists and antagonists in a model of short term, unilateral, carrageenan-induced…”
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Global cerebral blood flow decreases during pain by Coghill, R C, Sang, C N, Berman, K F, Bennett, G J, Iadarola, M J

“…Positron emission tomography studies have identified a common set of brain regions activated by pain. No studies, however, have quantitatively examined…”
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Good Pain, Bad Pain by Ladarola, Michael J., Caudle, Robert M.

“…Pain is never a good thing, right? With this view, investigators in the field of pain research have concentrated on mapping pain pathways and pharmacologically…”
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