Search Results - "IZQUIERDO, Alicia"

Functional Heterogeneity within Rat Orbitofrontal Cortex in Reward Learning and Decision Making by Izquierdo, Alicia

“…Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is divided into the medial orbital area, ventral orbital area,…”
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The basolateral amygdala in reward learning and addiction by Wassum, Kate M, Izquierdo, Alicia

“…Sophisticated behavioral paradigms partnered with the emergence of increasingly selective techniques to target the basolateral amygdala (BLA) have resulted in…”
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Reversal learning as a measure of impulsive and compulsive behavior in addictions by Izquierdo, Alicia, Jentsch, J. David

“…Background Our ability to measure the cognitive components of complex decision-making across species has greatly facilitated our understanding of its…”
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Complementary contributions of basolateral amygdala and orbitofrontal cortex to value learning under uncertainty by Stolyarova, Alexandra, Izquierdo, Alicia

“…We make choices based on the values of expected outcomes, informed by previous experience in similar settings. When the outcomes of our decisions consistently…”
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Brief Uncontrollable Stress Causes Dendritic Retraction in Infralimbic Cortex and Resistance to Fear Extinction in Mice by Izquierdo, Alicia, Wellman, Cara L, Holmes, Andrew

“…Extinction of conditioned fear responses is an active learning process resulting from the repeated presentation of a conditioned stimulus in the absence of the…”
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Orbitofrontal Cortex and Amygdala Contributions to Affect and Action in Primates by MURRAY, ELISABETH A., IZQUIERDO, ALICIA

“…:  The amygdala and orbitofrontal cortex (OFC) work together as part of the neural circuitry guiding goal‐directed behavior. This chapter explores the way in…”
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Sex-dependent effects of chronic intermittent voluntary alcohol consumption on attentional, not motivational, measures during probabilistic learning and reversal by Aguirre, Claudia G, Stolyarova, Alexandra, Das, Kanak, Kolli, Saisriya, Marty, Vincent, Ray, Lara, Spigelman, Igor, Izquierdo, Alicia

“…Forced alcohol (ethanol, EtOH) exposure has been shown to cause significant impairments on reversal learning, a widely-used assay of cognitive flexibility,…”
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Translational opportunities in animal and human models to study alcohol use disorder by Nieto, Steven J., Grodin, Erica N., Aguirre, Claudia G., Izquierdo, Alicia, Ray, Lara A.

“…Animal and human laboratory paradigms offer invaluable approaches to study the complex etiologies and mechanisms of alcohol use disorder (AUD). We contend that…”
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Bilateral Orbital Prefrontal Cortex Lesions in Rhesus Monkeys Disrupt Choices Guided by Both Reward Value and Reward Contingency by Izquierdo, Alicia, Suda, Robin K, Murray, Elisabeth A

“…The orbital prefrontal cortex (PFo) operates as part of a network involved in reward-based learning and goal-directed behavior. To test whether the PFo is…”
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Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys by Woo, Jae Hyung, Aguirre, Claudia G., Bari, Bilal A., Tsutsui, Ken-Ichiro, Grabenhorst, Fabian, Cohen, Jeremiah Y., Schultz, Wolfram, Izquierdo, Alicia, Soltani, Alireza

“…Despite being unpredictable and uncertain, reward environments often exhibit certain regularities, and animals navigating these environments try to detect and…”
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Selective Bilateral Amygdala Lesions in Rhesus Monkeys Fail to Disrupt Object Reversal Learning by Izquierdo, Alicia, Murray, Elisabeth A

“…Neuropsychological studies in nonhuman primates have led to the view that the amygdala plays an essential role in stimulus-reward association. The main…”
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Correction to: Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys by Woo, Jae Hyung, Aguirre, Claudia G., Bari, Bilal A., Tsutsui, Ken-Ichiro, Grabenhorst, Fabian, Cohen, Jeremiah Y., Schultz, Wolfram, Izquierdo, Alicia, Soltani, Alireza

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A hardware system for real-time decoding of in vivo calcium imaging data by Chen, Zhe, Blair, Garrett J, Guo, Changliang, Zhou, Jim, Romero-Sosa, Juan-Luis, Izquierdo, Alicia, Golshani, Peyman, Cong, Jason, Aharoni, Daniel, Blair, Hugh T

“…Epifluorescence miniature microscopes ('miniscopes') are widely used for in vivo calcium imaging of neural population activity. Imaging data are typically…”
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Selenite-induced cell death in Saccharomyces cerevisiae: protective role of glutaredoxins by IZQUIERDO, Alicia, CASAS, Celia, HERRERO, Enrique

“…Unlike in higher organisms, selenium is not essential for growth in Saccharomyces cerevisiae. In this species, it causes toxic effects at high concentrations…”
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Sex differences, learning flexibility, and striatal dopamine D1 and D2 following adolescent drug exposure in rats by Izquierdo, Alicia, Pozos, Hilda, Torre, Adrianna De La, DeShields, Simone, Cevallos, James, Rodriguez, Jonathan, Stolyarova, Alexandra

“…•Adolescent prescription drug exposure may impact learning and emotion in adulthood.•We found sex differences in discrimination learning and anxiety, assessed…”
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eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1 by García-Ortiz, Almudena, Martín-Cofreces, Noa B, Ibiza, Sales, Ortega, Ángel, Izquierdo-Álvarez, Alicia, Trullo, Antonio, Victor, Víctor M, Calvo, Enrique, Sot, Begoña, Martínez-Ruiz, Antonio, Vázquez, Jesús, Sánchez-Madrid, Francisco, Serrador, Juan M

“…The actin cytoskeleton coordinates the organization of signaling microclusters at the immune synapse (IS); however, the mechanisms involved remain poorly…”
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Basolateral amygdala lesions facilitate reward choices after negative feedback in rats by Izquierdo, Alicia, Darling, Chelsi, Manos, Nic, Pozos, Hilda, Kim, Charissa, Ostrander, Serena, Cazares, Victor, Stepp, Haley, Rudebeck, Peter H

“…The orbitofrontal cortex (OFC) and basolateral amygdala (BLA) constitute part of a neural circuit important for adaptive, goal-directed learning. One task…”
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Ebselen impairs cellular oxidative state and induces endoplasmic reticulum stress and activation of crucial mitogen‐activated protein kinases in pancreatic tumour AR42J cells by Santofimia‐Castaño, Patricia, Izquierdo‐Alvarez, Alicia, Plaza‐Davila, María, Martinez‐Ruiz, Antonio, Fernandez‐Bermejo, Miguel, Mateos‐Rodriguez, Jose M., Salido, Gines M., Gonzalez, Antonio

“…Ebselen (2‐phenyl‐1,2‐benzisoselenazol‐3(2H)‐one) is an organoselenium radical scavenger compound, which has strong antioxidant and anti‐inflammatory effects…”
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Regulation of SCFTIR1/AFBs E3 ligase assembly by S-nitrosylation of Arabidopsis SKP1-like1 impacts on auxin signaling by Iglesias, María José, Terrile, María Cecilia, Correa-Aragunde, Natalia, Colman, Silvana Lorena, Izquierdo-Álvarez, Alicia, Fiol, Diego Fernando, París, Ramiro, Sánchez-López, Nuria, Marina, Anabel, Calderón Villalobos, Luz Irina A., Estelle, Mark, Lamattina, Lorenzo, Martínez-Ruiz, Antonio, Casalongué, Claudia Anahí

“…The F-box proteins (FBPs) TIR1/AFBs are the substrate recognition subunits of SKP1–cullin–F-box (SCF) ubiquitin ligase complexes and together with Aux/IAAs…”
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S-Nitrosation of E3 Ubiquitin Ligase Complex Components Regulates Hormonal Signalings in Arabidopsis by Terrile, Maria Cecilia, Tebez, Nuria Malena, Colman, Silvana Lorena, Mateos, Julieta Lisa, Morato-López, Esperanza, Sánchez-López, Nuria, Izquierdo-Álvarez, Alicia, Marina, Anabel, Calderón Villalobos, Luz Irina A, Estelle, Mark, Martínez-Ruiz, Antonio, Fiol, Diego Fernando, Casalongué, Claudia Anahí, Iglesias, María José

“…E3 ubiquitin ligases mediate the last step of the ubiquitination pathway in the ubiquitin-proteasome system (UPS). By targeting transcriptional regulators for…”
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