Search Results - "IYER, R"

The therapeutic potential of second and third generation CB1R antagonists by Cinar, Resat, Iyer, Malliga R., Kunos, George

“…Endocannabinoids acting via CB1 receptors (CB1R) play a critical role in regulating energy homeostasis, which was the rationale for the pharmaceutical…”
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Letter to the editor concerning “Denosumab Treatment for Giant Cell Tumor of the Spine Including the Sacrum” by Iyer, R Dinesh

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Best Practices for Handling Missing Data by Srijan, Shukla, Rajagopalan, Iyer R.

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Tears and Eyewear in Forensic Investigation—A Review by Aparna, R., Shanti Iyer, R.

“…•Tears can be considered as a powerful forensic evidence.•Characteristics of the eye can be used for personal identification.•Spectacles and contact lenses act…”
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Authorship trends in The Lancet Global Health by Iyer, Adithi R

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Highly efficient Cas9-mediated transcriptional programming by Chavez, Alejandro, Scheiman, Jonathan, Vora, Suhani, Pruitt, Benjamin W, Tuttle, Marcelle, P R Iyer, Eswar, Lin, Shuailiang, Kiani, Samira, Guzman, Christopher D, Wiegand, Daniel J, Ter-Ovanesyan, Dmitry, Braff, Jonathan L, Davidsohn, Noah, Housden, Benjamin E, Perrimon, Norbert, Weiss, Ron, Aach, John, Collins, James J, Church, George M

“…The fusion of three transcriptional activation domains to a nuclease-deficient Cas9 achieves robust induction of gene expression and can induce differentiation…”
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The Neuromuscular Junction: Roles in Aging and Neuromuscular Disease by Iyer, Shama R, Shah, Sameer B, Lovering, Richard M

“…The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron and the skeletal muscle fiber and is crucial for conversion of…”
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Resource-constrained product development: Implications for green marketing and green supply chains by Sharma, Arun, Iyer, Gopalkrishnan R.

“…While academic debates and practical approaches to green marketing have matured over the past few decades, one central conundrum that has remained unresolved…”
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DNA Mismatch Repair:  Functions and Mechanisms by Iyer, Ravi R, Pluciennik, Anna, Burdett, Vickers, Modrich, Paul L

“…Iyer et al delve into the complex mechanism of base mismatches in DNA. Studies in DNA mismatch repair are discussed…”
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Synthetic evolutionary origin of a proofreading reverse transcriptase by Ellefson, Jared W., Gollihar, Jimmy, Shroff, Raghav, Shivram, Haridha, Iyer, Vishwanath R., Ellington, Andrew D.

“…Most reverse transcriptase (RT) enzymes belong to a single protein family of ancient evolutionary origin. These polymerases are inherently error prone, owing…”
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Crystal Structure of the Human Cannabinoid Receptor CB2 by Li, Xiaoting, Hua, Tian, Vemuri, Kiran, Ho, Jo-Hao, Wu, Yiran, Wu, Lijie, Popov, Petr, Benchama, Othman, Zvonok, Nikolai, Locke, K’ara, Qu, Lu, Han, Gye Won, Iyer, Malliga R., Cinar, Resat, Coffey, Nathan J., Wang, Jingjing, Wu, Meng, Katritch, Vsevolod, Zhao, Suwen, Kunos, George, Bohn, Laura M., Makriyannis, Alexandros, Stevens, Raymond C., Liu, Zhi-Jie

“…The cannabinoid receptor CB2 is predominately expressed in the immune system, and selective modulation of CB2 without the psychoactivity of CB1 has therapeutic…”
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DNA Triplet Repeat Expansion and Mismatch Repair by Iyer, Ravi R, Pluciennik, Anna, Napierala, Marek, Wells, Robert D

“…DNA mismatch repair is a conserved antimutagenic pathway that maintains genomic stability through rectification of DNA replication errors and attenuation of…”
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Letter to the editor concerning “Comparative analysis of the biomechanical behavior of anterograde/retrograde nailing in supracondylar femoral fractures” by Dinesh Iyer, R, Dubey, Siddharth

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An Experimental Study on Characterizing Coal Bed Methane (CBM) Fines Production and Migration of Mineral Matter in Coal Beds by Massarotto, Paul, Iyer, R. S, Elma, Muthia, Nicholson, Timothy

“…Drilling through coal beds and high initial fluid production rates can lead to shear and compressive failure of coal, resulting in the creation of coal fines…”
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Widespread misinterpretable ChIP-seq bias in yeast by Park, Daechan, Lee, Yaelim, Bhupindersingh, Gurvani, Iyer, Vishwanath R

“…Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is widely used to detect genome-wide interactions between a protein of interest and DNA in…”
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Identification and removal of sequencing artifacts produced by mispriming during reverse transcription in multiple RNA-seq technologies by Shivram, Haridha, Iyer, Vishwanath R

“…The quality of RNA sequencing data relies on specific priming by the primer used for reverse transcription (RT-primer). Nonspecific annealing of the RT-primer…”
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The SPHINX M-dwarf Spectral Grid. I. Benchmarking New Model Atmospheres to Derive Fundamental M-dwarf Properties by Iyer, Aishwarya R., Line, Michael R., Muirhead, Philip S., Fortney, Jonathan J., Gharib-Nezhad, Ehsan

“…About 70%–80% of stars in our solar and Galactic neighborhood are M dwarfs. They span a range of low masses and temperatures relative to solar-type stars,…”
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Letter to the editor concerning “M. Burkus, F. Tömböl and N. Wiegand et al., Physeal-sparing unreamed locked intramedullary nailing for adolescent tibial fractures, Injury, https://doi.org/10.1016/j.injury.2020.02.049” by Iyer, R. Dinesh, Dubey, Siddharth

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The ATP-dependent chromatin remodeler Chd1 is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes by Lee, Yaelim, Park, Daechan, Iyer, Vishwanath R

“…Chd1 (Chromodomain Helicase DNA Binding Protein 1) is a conserved ATP-dependent chromatin remodeler that maintains the nucleosomal structure of chromatin, but…”
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Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer by Zhang, Dingxiao, Park, Daechan, Zhong, Yi, Lu, Yue, Rycaj, Kiera, Gong, Shuai, Chen, Xin, Liu, Xin, Chao, Hsueh-Ping, Whitney, Pamela, Calhoun-Davis, Tammy, Takata, Yoko, Shen, Jianjun, Iyer, Vishwanath R., Tang, Dean G.

“…The prostate gland mainly contains basal and luminal cells constructed as a pseudostratified epithelium. Annotation of prostate epithelial transcriptomes…”
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