Search Results - "IX, Joachim"

The Promise of Tubule Biomarkers in Kidney Disease: A Review by Ix, Joachim H., Shlipak, Michael G.

“…For over 70 years, serum creatinine has remained the primary index for detection and monitoring of kidney disease. Tubulointerstitial damage and fibrosis are…”
Get full text

Diagnosis and Management of Osteoporosis in Advanced Kidney Disease: A Review by Ginsberg, Charles, Ix, Joachim H.

“…Osteoporosis and fractures are common in persons with advanced chronic kidney disease (CKD) and on maintenance dialysis. Although the diagnosis of osteoporosis…”
Get full text

New Insights into Vitamin D Metabolism in Kidney Disease and Transplant by Ginsberg, Charles, Ix, Joachim H.

Get full text

Binder Blunder in CKD by Ix, Joachim H

Get full text

New Insights into the Effects of Etelcalcetide on Bone Health by Ginsberg, Charles, Ix, Joachim H

Get full text

Implications of Oxalate as a Novel Risk Factor for Chronic Kidney Disease by Ix, Joachim H

Get more information

Kidney clearance of fibroblast growth factor-23 in humans by Sharma, Shilpa, Ix, Joachim H.

“…Recent studies have shed light on factors influencing FGF23 regulation in terms of its production and cleavage. However, less is known about FGF23 elimination…”
Get full text

Rethinking Albuminuria in Low-Risk Patients and a Call for Urine Albumin Standardization by Seegmiller, Jesse C, Ix, Joachim H

Get full text

Executive summary of the KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease by Cheung, Alfred K, Chang, Tara I, Cushman, William C, Furth, Susan L, Hou, Fan Fan, Ix, Joachim H, Knoll, Gregory A, Muntner, Paul, Pecoits-Filho, Roberto, Sarnak, Mark J, Tobe, Sheldon W, Tomson, Charles R V, Lytvyn, Lyubov, Craig, Jonathan C, Tunnicliffe, David J, Howell, Martin, Tonelli, Marcello, Cheung, Michael, Earley, Amy, Mann, Johannes F E

“…The Kidney Disease: Improving Global Outcomes (KDIGO) 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease for…”
Get more information

Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events by Criqui, Michael H, Denenberg, Julie O, Ix, Joachim H, McClelland, Robyn L, Wassel, Christina L, Rifkin, Dena E, Carr, Jeffrey J, Budoff, Matthew J, Allison, Matthew A

“…IMPORTANCE Coronary artery calcium (CAC), measured by computed tomography (CT), has strong predictive value for incident cardiovascular disease (CVD) events…”
Get full text

Effects of Intensive BP Control in CKD by Cheung, Alfred K, Rahman, Mahboob, Reboussin, David M, Craven, Timothy E, Greene, Tom, Kimmel, Paul L, Cushman, William C, Hawfield, Amret T, Johnson, Karen C, Lewis, Cora E, Oparil, Suzanne, Rocco, Michael V, Sink, Kaycee M, Whelton, Paul K, Wright, Jr, Jackson T, Basile, Jan, Beddhu, Srinivasan, Bhatt, Udayan, Chang, Tara I, Chertow, Glenn M, Chonchol, Michel, Freedman, Barry I, Haley, William, Ix, Joachim H, Katz, Lois A, Killeen, Anthony A, Papademetriou, Vasilios, Ricardo, Ana C, Servilla, Karen, Wall, Barry, Wolfgram, Dawn, Yee, Jerry

“…The appropriate target for BP in patients with CKD and hypertension remains uncertain. We report prespecified subgroup analyses of outcomes in participants…”
Get full text

Effects of Intensive Blood Pressure Lowering on Kidney Tubule Injury in CKD: A Longitudinal Subgroup Analysis in SPRINT by Malhotra, Rakesh, Craven, Timothy, Ambrosius, Walter T., Killeen, Anthony A., Haley, William E., Cheung, Alfred K., Chonchol, Michel, Sarnak, Mark, Parikh, Chirag R., Shlipak, Michael G., Ix, Joachim H.

“…Random assignment to the intensive systolic blood pressure (SBP) arm (<120mmHg) in the Systolic Blood Pressure Intervention Trial (SPRINT) resulted in more…”
Get full text

BP Measurement in Clinical Practice: Time to SPRINT to Guideline-Recommended Protocols by Drawz, Paul E, Ix, Joachim H

“…Hypertension is the leading chronic disease risk factor in the world and is especially important in patients with CKD, nearly 90% of whom have hypertension…”
Get full text

Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of End-Stage Renal Disease and Mortality by Coresh, Josef, Turin, Tanvir Chowdhury, Matsushita, Kunihiro, Sang, Yingying, Ballew, Shoshana H, Appel, Lawrence J, Arima, Hisatomi, Chadban, Steven J, Cirillo, Massimo, Djurdjev, Ognjenka, Green, Jamie A, Heine, Gunnar H, Inker, Lesley A, Irie, Fujiko, Ishani, Areef, Ix, Joachim H, Kovesdy, Csaba P, Marks, Angharad, Ohkubo, Takayoshi, Shalev, Varda, Shankar, Anoop, Wen, Chi Pang, de Jong, Paul E, Iseki, Kunitoshi, Stengel, Benedicte, Gansevoort, Ron T, Levey, Andrew S

“…IMPORTANCE: The established chronic kidney disease (CKD) progression end point of end-stage renal disease (ESRD) or a doubling of serum creatinine…”
Get full text

Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial by Williamson, Jeff D, Supiano, Mark A, Applegate, William B, Berlowitz, Dan R, Campbell, Ruth C, Chertow, Glenn M, Fine, Larry J, Haley, William E, Hawfield, Amret T, Ix, Joachim H, Kitzman, Dalane W, Kostis, John B, Krousel-Wood, Marie A, Launer, Lenore J, Oparil, Suzanne, Rodriguez, Carlos J, Roumie, Christianne L, Shorr, Ronald I, Sink, Kaycee M, Wadley, Virginia G, Whelton, Paul K, Whittle, Jeffrey, Woolard, Nancy F, Wright, Jackson T, Pajewski, Nicholas M

“…IMPORTANCE: The appropriate treatment target for systolic blood pressure (SBP) in older patients with hypertension remains uncertain. OBJECTIVE: To evaluate…”
Get full text

Biomarkers of Kidney Tubule Health, CKD Progression, and Acute Kidney Injury in SPRINT (Systolic Blood Pressure Intervention Trial) Participants by Bullen, Alexander L., Katz, Ronit, Jotwani, Vasantha, Garimella, Pranav S., Lee, Alexandra K., Estrella, Michelle M., Shlipak, Michael G., Ix, Joachim H.

“…The Systolic Blood Pressure Intervention Trial (SPRINT) compared the effect of intensive versus standard systolic blood pressure targets on cardiovascular…”
Get full text

Effects of Nicotinamide and Lanthanum Carbonate on Serum Phosphate and Fibroblast Growth Factor-23 in CKD: The COMBINE Trial by Ix, Joachim H, Isakova, Tamara, Larive, Brett, Raphael, Kalani L, Raj, Dominic S, Cheung, Alfred K, Sprague, Stuart M, Fried, Linda F, Gassman, Jennifer J, Middleton, John P, Flessner, Michael F, Block, Geoffrey A, Wolf, Myles

“…Higher serum phosphate and fibroblast growth factor-23 (FGF23) levels may be modifiable to prevent cardiovascular disease in CKD. Short-term studies have…”
Get full text

The Spectrum of Subclinical Primary Aldosteronism and Incident Hypertension: A Cohort Study by Brown, Jenifer M, Robinson-Cohen, Cassianne, Luque-Fernandez, Miguel Angel, Allison, Matthew A, Baudrand, Rene, Ix, Joachim H, Kestenbaum, Bryan, de Boer, Ian H, Vaidya, Anand

“…Primary aldosteronism is recognized as a severe form of renin-independent aldosteronism that results in excessive mineralocorticoid receptor (MR) activation…”
Get full text

Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5: A Systematic Review and Meta-analysis by Malhotra, Rakesh, Nguyen, Hoang Anh, Benavente, Oscar, Mete, Mihriye, Howard, Barbara V, Mant, Jonathan, Odden, Michelle C, Peralta, Carmen A, Cheung, Alfred K, Nadkarni, Girish N, Coleman, Ruth L, Holman, Rury R, Zanchetti, Alberto, Peters, Ruth, Beckett, Nigel, Staessen, Jan A, Ix, Joachim H

“…Trials in patients with hypertension have demonstrated that intensive blood pressure (BP) lowering reduces the risk of cardiovascular disease and all-cause…”
Get more information

Urinary Uromodulin and Risk of Urinary Tract Infections: The Cardiovascular Health Study by Garimella, Pranav S., MD, MPH, Bartz, Traci M., PhD, Ix, Joachim H., MD, MAS, Chonchol, Michel, MD, Shlipak, Michael G., MD, MPH, Devarajan, Prasad, MD, Bennett, Michael R., PhD, Sarnak, Mark J., MD, MS

“…Background Laboratory studies suggest that urinary uromodulin, the most common protein in the urine of healthy adults, may protect against urinary tract…”
Get full text