Search Results - "IWATA, Naohiro"

Mechanisms and Safety of Antidepressant-Like Effect of Nutmeg in Mice by Iwata, Naohiro, Kobayashi, Daisuke, Kawashiri, Takehiro, Kubota, Toshio, Kawano, Kotomi, Yamamuro, Yuki, Miyagi, Anna, Deguchi, Yuya, Chijimatsu, Takeshi, Shimazoe, Takao

“…Nutmeg, a dried seed kernel of a tall evergreen Myristicaceae tree, is widely used as a spice and herbal medicine and is known to have antidepressant-like…”
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Association between immune checkpoint inhibitor‐induced myocarditis and concomitant use of thiazide diuretics by Mitsuboshi, Satoru, Hamano, Hirofumi, Niimura, Takahiro, Ozaki, Aya F., Patel, Pranav M., Lin, Tsung‐Jen, Tanaka, Yuta, Kimura, Ikuya, Iwata, Naohiro, Shiromizu, Shoya, Chuma, Masayuki, Koyama, Toshihiro, Yamanishi, Yoshihiro, Kanda, Yasunari, Ishizawa, Keisuke, Zamami, Yoshito

“…Although an association has been reported between diuretics and myocarditis, it is unclear whether the risk of immune checkpoint inhibitor (ICI)‐induced…”
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Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats by Asano, Takashi, Xuan, Meiyan, Iwata, Naohiro, Takayama, Jun, Hayashi, Kousuke, Kato, Yosuke, Aoyama, Toshiya, Sugo, Hiroshi, Matsuzaki, Hirokazu, Yuan, Bo, Kamiuchi, Shinya, Hibino, Yasuhide, Sakamoto, Takeshi, Okazaki, Mari

“…Tissue plasminogen activator, aiming to restore cerebral blood flow (CBF), has been used for acute ischemic strokes in clinics; however, its narrow therapeutic…”
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Efficacy of Computed Tomography-Based Evaluation of Myocardial Extracellular Volume Combined With Red Flags for Early Screening of Concealed Cardiac Amyloidosis in Patients With Atrial Fibrillation by Yamasaki, Hirochika, Kondo, Hidekazu, Shiroo, Tomoaki, Iwata, Naohiro, Masuda, Teruaki, Makita, Taiki, Iwabuchi, Yuki, Tanazawa, Kota, Takahashi, Masaki, Ono, Yuma, Ogawa, Naoko, Harada, Taisuke, Mitarai, Kazuki, Yamauchi, Shuichiro, Takano, Masayuki, Kodama, Nozomi, Hirota, Kei, Miyoshi, Miho, Yonezu, Keisuke, Tawara, Katsunori, Abe, Ichitaro, Saito, Shotaro, Fukui, Akira, Fukuda, Tomoko, Akioka, Hidefumi, Shinohara, Tetsuji, Akiyoshi, Kumiko, Teshima, Yasushi, Yufu, Kunio, Daa, Tsutomu, Matsubara, Etsuro, Asayama, Yoshiki, Ueda, Mitsuharu, Takahashi, Naohiko

“…Background: The prevalence of transthyretin amyloid cardiomyopathy (ATTR-CM) in atrial fibrillation (AF) patients remains unclear. We explored the efficacy of…”
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Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87 by Yuan, Bo, Li, Jingmei, Miyashita, Shin-Ich, Kikuchi, Hidetomo, Xuan, Meiyan, Matsuzaki, Hirokazu, Iwata, Naohiro, Kamiuchi, Shinya, Sunaga, Katsuyoshi, Sakamoto, Takeshi, Hibino, Yasuhide, Okazaki, Mari

“…The cytotoxicity of a trivalent arsenic derivative (arsenite, AsIII) combined with arenobufagin or gamabufotalin was evaluated in human U-87 glioblastoma…”
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Anxiolytic-like effects of hochuekkito in lipopolysaccharide-treated mice involve interleukin-6 inhibition by Ushio, Soichiro, Wada, Yudai, Nakamura, Mizuki, Matsumoto, Daiki, Hoshika, Kota, Shiromizu, Shoya, Iwata, Naohiro, Esumi, Satoru, Kajizono, Makoto, Kitamura, Yoshihisa, Sendo, Toshiaki

“…Hochuekkito (HET) is a Kampo medicine used to treat postoperative and post-illness general malaise and decreased motivation. HET is known to regulate immunity…”
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Protective Effects of Ferulic Acid against Chronic Cerebral Hypoperfusion-Induced Swallowing Dysfunction in Rats by Asano, Takashi, Matsuzaki, Hirokazu, Iwata, Naohiro, Xuan, Meiyan, Kamiuchi, Shinya, Hibino, Yasuhide, Sakamoto, Takeshi, Okazaki, Mari

“…Ferulic acid (FA), a phenolic phytochemical, has been reported to exert antioxidative and neuroprotective effects. In this study, we investigated the…”
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Interdental Plaque Microbial Community Changes under In Vitro Violet LED Irradiation by Wang, Dan, Nambu, Takayuki, Tanimoto, Hiroaki, Iwata, Naohiro, Yoshikawa, Kazushi, Okinaga, Toshinori, Yamamoto, Kazuyo

“…Oral microbiome dysbiosis has important links to human health and disease. Although photodynamic therapy influences microbiome diversity, the specific effect…”
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Orally administrated ascorbic acid suppresses neuronal damage and modifies expression of SVCT2 and GLUT1 in the brain of diabetic rats with cerebral ischemia-reperfusion by Iwata, Naohiro, Okazaki, Mari, Xuan, Meiyan, Kamiuchi, Shinya, Matsuzaki, Hirokazu, Hibino, Yasuhide

“…Diabetes mellitus is known to exacerbate cerebral ischemic injury. In the present study, we investigated antiapoptotic and anti-inflammatory effects of oral…”
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Effects of Etanercept against Transient Cerebral Ischemia in Diabetic Rats by Hibino, Yasuhide, Okazaki, Mari, Matsuzaki, Hirokazu, Xuan, Meiyan, Takayama, Hiroko, Iwata, Naohiro, Kamiuchi, Shinya

“…Diabetes mellitus is known to exacerbate acute cerebral ischemic injury. Previous studies have demonstrated that infarction volumes caused by transient…”
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保険薬局薬剤師におけるエビデンス創出に対する意識 : 岡山県薬剤師会会員に対する大規模実態調査 by 松本准a, b, c, 板野円香b, 岩田直大b, 大呂真史b, 北風智佳子b, 廣田あゆ子b, 槇野克彦b, 立野朋志b, 寺井竜平b, 監物英男b, 伊達元英b

“…「緒言」近年, 薬剤師業務の多様化に伴い, 政府及び国民からの保険薬局薬剤師に対するニーズは大きく変化している. 厚生労働省は, 2025年問題を見据えて地域包括ケアシステムの構築を推進しており, 健康サポート薬局の認定等を通じ, かかりつけ薬局・かかりつけ薬剤師が地域医療に果たす役割に大きな期待を寄せている…”
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XPS analysis of the dentin irradiated by Er:YAG laser by OMAE, Masanori, SHINNOU, Yasuo, TANAKA, Kumiko, ABO, Tomoko, NAKATA, Takashi, SUZUKI, Koichiro, HATSUOKA, Yoshinori, IWATA, Naohiro, YOSHIKAWA, Kazushi, NISHITANI, Yoshihiro, YAMAMOTO, Kazuyo, YOSHIYAMA, Masahiro

“…The aim of this study was to investigate the effect of Er:YAG laser irradiation on human dentin surface using X-ray photoelectron spectroscopy (XPS). 10 human…”
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Protective Effects of Oral Administrated Ascorbic Acid against Oxidative Stress and Neuronal Damage after Cerebral Ischemia/Reperfusion in Diabetic Rats by Iwata, Naohiro, Okazaki, Mari, Kamiuchi, Shinya, Hibino, Yasuhide

“…Diabetes enhances oxidative stress and exacerbates acute ischemic injury. Previous studies have demonstrated that infarct volumes were greater in diabetic…”
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Antidepressant-like effects of a water-soluble extract from the culture medium of Ganoderma lucidum mycelia in rats by Matsuzaki, Hirokazu, Shimizu, Yuta, Iwata, Naohiro, Kamiuchi, Shinya, Suzuki, Fumiko, Iizuka, Hiroshi, Hibino, Yasuhide, Okazaki, Mari

“…Ganoderma lucidum is a popular medicinal mushroom used for promoting health and longevity in Asian countries. Previously, we reported that a water-soluble…”
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A comparison between the adverse event profiles of patients receiving palbociclib and abemaciclib: analysis of two real-world databases by Takeda, Tatsuaki, Sugimoto, Shiho, Matsumoto, Jun, Iwata, Naohiro, Nakamoto, Akihiko, Ozaki, Aya Fukuma, Hamano, Hirofumi, Ariyoshi, Noritaka, Zamami, Yoshito

“…Background Palbociclib and abemaciclib are cyclin-dependent kinase (CDK) 4/6 inhibitors currently used to treat breast cancer. Although their therapeutic…”
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Mechanisms and safety of antidepressant-like effect of nutmeg in mice by Iwata, Naohiro, Kobayashi, Daisuke, Kawashiri, Takehiro, Kubota, Toshio, Kawano, Kotomi, Yamamuro, Yuki, Miyagi, Anna, Deguchi, Yuya, Chijimatsu, Takeshi, Shimazoe, Takao

“…Nutmeg, a dried seed kernel of a tall evergreen Myristicaceae tree, is widely used as a spice and herbal medicine and is known to have antidepressant-like…”
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Adverse events of nivolumab plus ipilimumab versus nivolumab plus cabozantinib: a real-world pharmacovigilance study by Oka, Yurie, Matsumoto, Jun, Takeda, Tatsuaki, Iwata, Naohiro, Niimura, Takahiro, Ozaki, Aya Fukuma, Bekku, Kensuke, Hamano, Hirofumi, Araki, Motoo, Ishizawa, Keisuke, Zamami, Yoshito, Ariyoshi, Noritaka

“…Background No head-to-head clinical trials have compared the differences in adverse events (AEs) between nivolumab plus ipilimumab (NIVO-IPI) and nivolumab…”
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Significance of UGT1A6, UGT1A9, and UGT2B7 genetic variants and their mRNA expression in the clinical outcome of renal cell carcinoma by Matsumoto, Jun, Nishimoto, Anzu, Watari, Shogo, Ueki, Hideo, Shiromizu, Shoya, Iwata, Naohiro, Takeda, Tatsuaki, Ushio, Soichiro, Kajizono, Makoto, Fujiyoshi, Masachika, Koyama, Toshihiro, Araki, Motoo, Wada, Koichiro, Zamami, Yoshito, Nasu, Yasutomo, Ariyoshi, Noritaka

“…UDP-glucuronosyltransferase (UGT) metabolizes a number of endogenous and exogenous substrates. Renal cells express high amounts of UGT; however, the…”
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Awareness about the Establishment of Clinical Evidence among Community Pharmacists: A Large-scale Survey among Members of the Okayama Pharmaceutical Association by Matsumoto, Jun, Itano, Madoka, Iwata, Naohiro, Oro, Masafumi, Kitakaze, Chikako, Hirota, Ayuko, Makino, Katsuhiko, Tateno, Tomoyuki, Terai, Ryohei, Kenmotsu, Hideo, Date, Motohide

“…Community pharmacists in Japan participate in many important clinical cases involving drug therapies. This involvement should be researched and widely…”
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Efficacy of Computed Tomography-Based Evaluation of Myocardial Extracellular Volume Combined With Red Flags for Early Screening of Concealed Cardiac Amyloidosis in Patients With Atrial Fibrillation by Yamasaki, Hirochika, Kondo, Hidekazu, Shiroo, Tomoaki, Iwata, Naohiro, Masuda, Teruaki, Makita, Taiki, Iwabuchi, Yuki, Tanazawa, Kota, Takahashi, Masaki, Ono, Yuma, Ogawa, Naoko, Harada, Taisuke, Mitarai, Kazuki, Yamauchi, Shuichiro, Takano, Masayuki, Kodama, Nozomi, Hirota, Kei, Miyoshi, Miho, Yonezu, Keisuke, Tawara, Katsunori, Abe, Ichitaro, Saito, Shotaro, Fukui, Akira, Fukuda, Tomoko, Akioka, Hidefumi, Shinohara, Tetsuji, Akiyoshi, Kumiko, Teshima, Yasushi, Yufu, Kunio, Daa, Tsutomu, Matsubara, Etsuro, Asayama, Yoshiki, Ueda, Mitsuharu, Takahashi, Naohiko

“…Background: The prevalence of transthyretin amyloid cardiomyopathy (ATTR-CM) in atrial fibrillation (AF) patients remains unclear. We explored the efficacy of…”
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