Search Results - "IWATA, Nakao"

Memantine monotherapy for Alzheimer's disease: a systematic review and meta-analysis by Matsunaga, Shinji, Kishi, Taro, Iwata, Nakao

“…We performed an updated meta-analysis of randomized placebo-controlled trials testing memantine monotherapy for patients with Alzheimer's disease (AD). The…”
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Mood stabilizers and/or antipsychotics for bipolar disorder in the maintenance phase: a systematic review and network meta-analysis of randomized controlled trials by Kishi, Taro, Ikuta, Toshikazu, Matsuda, Yuki, Sakuma, Kenji, Okuya, Makoto, Mishima, Kazuo, Iwata, Nakao

“…We searched Embase, PubMed, and CENTRAL from inception until 22 May 2020 to investigate which antipsychotics and/or mood stabilizers are better for patients…”
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Brain-Derived Neurotrophic Factor and Major Depressive Disorder: Evidence from Meta-Analyses by Kishi, Taro, Yoshimura, Reiji, Ikuta, Toshikazu, Iwata, Nakao

“…Accumulating evidence suggests that brain-derived neurotrophic factor (BDNF) is associated with the pathophysiology of major depressive disorder (MDD). In this…”
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Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases by Kanai, Masahiro, Akiyama, Masato, Takahashi, Atsushi, Matoba, Nana, Momozawa, Yukihide, Ikeda, Masashi, Iwata, Nakao, Ikegawa, Shiro, Hirata, Makoto, Matsuda, Koichi, Kubo, Michiaki, Okada, Yukinori, Kamatani, Yoichiro

“…Clinical measurements can be viewed as useful intermediate phenotypes to promote understanding of complex human diseases. To acquire comprehensive insights…”
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Polygenic risk score as clinical utility in psychiatry: a clinical viewpoint by Ikeda, Masashi, Saito, Takeo, Kanazawa, Tetsufumi, Iwata, Nakao

“…Genome-wide association studies (GWASs) have detected many susceptible variants for common diseases, including psychiatric disorders. However, because of the…”
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Differences in the incidence of lurasidone adverse events between depressive disorders and schizophrenia in double-blind, randomized, placebo-controlled trials: a meta-analysis by Kishi, Taro, Nakamura, Hiroshi, Iwata, Nakao

“…Rationale We conducted a meta-analysis of double-blind, randomized placebo-controlled trials of lurasidone (LUR) to examine the difference in the risk ratios…”
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Memantine for Alzheimer's Disease: An Updated Systematic Review and Meta-analysis by Kishi, Taro, Matsunaga, Shinji, Oya, Kazuto, Nomura, Ikuo, Ikuta, Toshikazu, Iwata, Nakao

“…The clinical benefit of memantine for Alzheimer's disease (AD) remains inconclusive. We performed an updated systematic review and meta-analysis of the…”
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Pharmacological treatment for bipolar mania: a systematic review and network meta-analysis of double-blind randomized controlled trials by Kishi, Taro, Ikuta, Toshikazu, Matsuda, Yuki, Sakuma, Kenji, Okuya, Makoto, Nomura, Ikuo, Hatano, Masakazu, Iwata, Nakao

“…A systematic review and random-effects model network meta-analysis was conducted to compare the efficacy, acceptability, tolerability, and safety of…”
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Suvorexant for Primary Insomnia: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials by Kishi, Taro, Matsunaga, Shinji, Iwata, Nakao

“…We performed a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials evaluating suvorexant for primary insomnia. Relevant…”
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Lemborexant vs suvorexant for insomnia: A systematic review and network meta-analysis by Kishi, Taro, Nomura, Ikuo, Matsuda, Yuki, Sakuma, Kenji, Okuya, Makoto, Ikuta, Toshikazu, Iwata, Nakao

“…We conducted a random-effects model network meta-analysis to examine differences between lemborexant and suvorexant in efficacy and safety outcomes for…”
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Genome-wide association study identifies 112 new loci for body mass index in the Japanese population by Akiyama, Masato, Okada, Yukinori, Kanai, Masahiro, Takahashi, Atsushi, Momozawa, Yukihide, Ikeda, Masashi, Iwata, Nakao, Ikegawa, Shiro, Hirata, Makoto, Matsuda, Koichi, Iwasaki, Motoki, Yamaji, Taiki, Sawada, Norie, Hachiya, Tsuyoshi, Tanno, Kozo, Shimizu, Atsushi, Hozawa, Atsushi, Minegishi, Naoko, Tsugane, Shoichiro, Yamamoto, Masayuki, Kubo, Michiaki, Kamatani, Yoichiro

“…Yoichiro Kamatani and colleagues perform a genome-wide association study (GWAS) for body mass index using data from 173,430 Japanese individuals. They find 85…”
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N-acetylcysteine as an adjunctive treatment for bipolar depression and major depressive disorder: a systematic review and meta-analysis of double-blind, randomized placebo-controlled trials by Kishi, Taro, Miyake, Nobumi, Okuya, Makoto, Sakuma, Kenji, Iwata, Nakao

“…Rationale It remains unclear whether using N-acetylcysteine as an adjunctive treatment has any benefit for bipolar depression and major depressive disorder…”
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Memantine add-on to antipsychotic treatment for residual negative and cognitive symptoms of schizophrenia: a meta-analysis by Kishi, Taro, Matsuda, Yuki, Iwata, Nakao

“…Rationale We examined whether memantine add-on to antipsychotic treatment is beneficial in schizophrenia treatment. Objective This systematic review and…”
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Comparative genetic architectures of schizophrenia in East Asian and European populations by Lam, Max, Chen, Chia-Yen, Li, Zhiqiang, Martin, Alicia R., Bryois, Julien, Ma, Xixian, Gaspar, Helena, Ikeda, Masashi, Benyamin, Beben, Brown, Brielin C., Liu, Ruize, Zhou, Wei, Guan, Lili, Kamatani, Yoichiro, Kim, Sung-Wan, Kubo, Michiaki, Kusumawardhani, Agung A. A. A., Liu, Chih-Min, Ma, Hong, Periyasamy, Sathish, Takahashi, Atsushi, Xu, Zhida, Yu, Hao, Zhu, Feng, Chen, Wei J., Faraone, Stephen, Glatt, Stephen J., He, Lin, Hyman, Steven E., Hwu, Hai-Gwo, McCarroll, Steven A., Neale, Benjamin M., Sklar, Pamela, Wildenauer, Dieter B., Yu, Xin, Zhang, Dai, Mowry, Bryan J., Lee, Jimmy, Holmans, Peter, Xu, Shuhua, Sullivan, Patrick F., Ripke, Stephan, O’Donovan, Michael C., Daly, Mark J., Qin, Shengying, Sham, Pak, Iwata, Nakao, Hong, Kyung S., Schwab, Sibylle G., Yue, Weihua, Tsuang, Ming, Liu, Jianjun, Ma, Xiancang, Kahn, René S., Shi, Yongyong, Huang, Hailiang

“…Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk globally. Large-scale schizophrenia genetic studies have reported…”
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Recurrence rates in stable bipolar disorder patients after drug discontinuation v. drug maintenance: a systematic review and meta-analysis by Kishi, Taro, Matsuda, Yuki, Sakuma, Kenji, Okuya, Makoto, Mishima, Kazuo, Iwata, Nakao

“…This random-effects model meta-analysis of double-blind, randomized placebo-controlled trials compared recurrence rates in bipolar disorder (BD) patients…”
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Association between circadian activity rhythms and mood episode relapse in bipolar disorder: a 12-month prospective cohort study by Esaki, Yuichi, Obayashi, Kenji, Saeki, Keigo, Fujita, Kiyoshi, Iwata, Nakao, Kitajima, Tsuyoshi

“…A significant proportion of patients with bipolar disorder experience mood episode relapses. We examined whether circadian activity rhythms were associated…”
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Aripiprazole vs. brexpiprazole for acute schizophrenia: a systematic review and network meta-analysis by Kishi, Taro, Ikuta, Toshikazu, Matsuda, Yuki, Sakuma, Kenji, Iwata, Nakao

“…Rationale What is the difference between aripiprazole and brexpiprazole? Objectives This systematic review, network meta-analysis of randomized trials…”
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Genome‐wide association studies of bipolar disorder: A systematic review of recent findings and their clinical implications by Ikeda, Masashi, Saito, Takeo, Kondo, Kenji, Iwata, Nakao

“…Recent advances in molecular genetics have enabled assessments of the associations among genetic variants (e.g., single‐nucleotide polymorphisms) and…”
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Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population by Suzuki, Ken, Akiyama, Masato, Ishigaki, Kazuyoshi, Kanai, Masahiro, Hosoe, Jun, Shojima, Nobuhiro, Hozawa, Atsushi, Kadota, Aya, Kuriki, Kiyonori, Naito, Mariko, Tanno, Kozo, Ishigaki, Yasushi, Hirata, Makoto, Matsuda, Koichi, Iwata, Nakao, Ikeda, Masashi, Sawada, Norie, Yamaji, Taiki, Iwasaki, Motoki, Ikegawa, Shiro, Maeda, Shiro, Murakami, Yoshinori, Wakai, Kenji, Tsugane, Shoichiro, Sasaki, Makoto, Yamamoto, Masayuki, Okada, Yukinori, Kubo, Michiaki, Kamatani, Yoichiro, Horikoshi, Momoko, Yamauchi, Toshimasa, Kadowaki, Takashi

“…To understand the genetics of type 2 diabetes in people of Japanese ancestry, we conducted A meta-analysis of four genome-wide association studies (GWAS;…”
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Efficacy and safety of antipsychotic treatments for schizophrenia: A systematic review and network meta-analysis of randomized trials in Japan by Kishi, Taro, Ikuta, Toshikazu, Sakuma, Kenji, Okuya, Makoto, Iwata, Nakao

“…We examined the efficacy and safety of using antipsychotic medication for schizophrenia using only randomized trials of antipsychotic for schizophrenia…”
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