Search Results - "IWANARI, Hiroko"

Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle by Horiuchi, Keiko, Kawamura, Takeshi, Iwanari, Hiroko, Ohashi, Riuko, Naito, Makoto, Kodama, Tatsuhiko, Hamakubo, Takao

“…Wilms' tumor 1-associating protein (WTAP) is a putative splicing regulator that is thought to be required for cell cycle progression through the stabilization…”
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Crystal structure of the anion exchanger domain of human erythrocyte band 3 by Arakawa, Takatoshi, Kobayashi-Yurugi, Takami, Alguel, Yilmaz, Iwanari, Hiroko, Hatae, Hinako, Iwata, Momi, Abe, Yoshito, Hino, Tomoya, Ikeda-Suno, Chiyo, Kuma, Hiroyuki, Kang, Dongchon, Murata, Takeshi, Hamakubo, Takao, Cameron, Alexander D., Kobayashi, Takuya, Hamasaki, Naotaka, Iwata, So

“…Anion exchanger 1 (AE1), also known as band 3 or SLC4A1, plays a key role in the removal of carbon dioxide from tissues by facilitating the exchange of…”
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Structure and mechanism of the mammalian fructose transporter GLUT5 by Nomura, Norimichi, Verdon, Grégory, Kang, Hae Joo, Shimamura, Tatsuro, Nomura, Yayoi, Sonoda, Yo, Hussien, Saba Abdul, Qureshi, Aziz Abdul, Coincon, Mathieu, Sato, Yumi, Abe, Hitomi, Nakada-Nakura, Yoshiko, Hino, Tomoya, Arakawa, Takatoshi, Kusano-Arai, Osamu, Iwanari, Hiroko, Murata, Takeshi, Kobayashi, Takuya, Hamakubo, Takao, Kasahara, Michihiro, Iwata, So, Drew, David

“…The altered activity of the fructose transporter GLUT5, an isoform of the facilitated-diffusion glucose transporter family, has been linked to disorders such…”
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Optical inactivation of synaptic AMPA receptors erases fear memory by Takemoto, Kiwamu, Iwanari, Hiroko, Tada, Hirobumi, Suyama, Kumiko, Sano, Akane, Nagai, Takeharu, Hamakubo, Takao, Takahashi, Takuya

“…Development of an optical method to inactivate synaptic receptors in mice with temporal precision will enable a better understanding of their roles in…”
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Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog by Asada, Hidetsugu, Horita, Shoichiro, Hirata, Kunio, Shiroishi, Mitsunori, Shiimura, Yuki, Iwanari, Hiroko, Hamakubo, Takao, Shimamura, Tatsuro, Nomura, Norimichi, Kusano-Arai, Osamu, Uemura, Tomoko, Suno, Chiyo, Kobayashi, Takuya, Iwata, So

“…Angiotensin II (AngII) plays a central role in regulating human blood pressure, which is mainly mediated by interactions between AngII and the…”
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G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody by Hino, Tomoya, Arakawa, Takatoshi, Iwanari, Hiroko, Yurugi-Kobayashi, Takami, Ikeda-Suno, Chiyo, Nakada-Nakura, Yoshiko, Kusano-Arai, Osamu, Weyand, Simone, Shimamura, Tatsuro, Nomura, Norimichi, Cameron, Alexander D., Kobayashi, Takuya, Hamakubo, Takao, Iwata, So, Murata, Takeshi

“…Determination of the crystal structure of the human A 2A adenosine receptor in complex with an inverse-agonist antibody shows that the allosteric site of the…”
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Prdm16 is crucial for progression of the multipolar phase during neural differentiation of the developing neocortex by Inoue, Mayuko, Iwai, Ryota, Tabata, Hidenori, Konno, Daijiro, Komabayashi-Suzuki, Mariko, Watanabe, Chisato, Iwanari, Hiroko, Mochizuki, Yasuhiro, Hamakubo, Takao, Matsuzaki, Fumio, Nagata, Koh-Ichi, Mizutani, Ken-Ichi

“…The precise control of neuronal migration and morphological changes during differentiation is essential for neocortical development. We hypothesized that the…”
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Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation by Chowdhury, A. M. Masudul Azad, Katoh, Hiroki, Hatanaka, Atsushi, Iwanari, Hiroko, Nakamura, Nanami, Hamakubo, Takao, Natsume, Tohru, Waku, Tsuyoshi, Kobayashi, Akira

“…Accumulated evidence suggests a physiological relationship between the transcription factor NRF3 (NFE2L3) and cancers. Under physiological conditions, NRF3 is…”
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111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis by Fujiwara, Kentaro, Tsuji, Atsushi B., Sudo, Hitomi, Sugyo, Aya, Akiba, Hiroki, Iwanari, Hiroko, Kusano-Arai, Osamu, Tsumoto, Kouhei, Momose, Toshimitsu, Hamakubo, Takao, Higashi, Tatsuya

“…Objective Cadherin-17 (CDH17) is a transmembrane protein that mediates cell–cell adhesion and is frequently expressed in adenocarcinomas, including gastric…”
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Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface by Yamashita, Takefumi, Mizohata, Eiichi, Nagatoishi, Satoru, Watanabe, Takahiro, Nakakido, Makoto, Iwanari, Hiroko, Mochizuki, Yasuhiro, Nakayama, Taisuke, Kado, Yuji, Yokota, Yuki, Matsumura, Hiroyoshi, Kawamura, Takeshi, Kodama, Tatsuhiko, Hamakubo, Takao, Inoue, Tsuyoshi, Fujitani, Hideaki, Tsumoto, Kouhei

“…To investigate favorable single amino acid substitutions that improve antigen-antibody interactions, alanine (Ala) mutagenesis scanning of the interfacial…”
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Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9 by Tachibana, Makoto, Ueda, Jun, Fukuda, Mikiko, Takeda, Naoki, Ohta, Tsutomu, Iwanari, Hiroko, Sakihama, Toshiko, Kodama, Tatsuhiko, Hamakubo, Takao, Shinkai, Yoichi

“…Histone H3 Lys 9 (H3-K9) methylation is a crucial epigenetic mark for transcriptional silencing. G9a is the major mammalian H3-K9 methyltransferase that…”
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Author Correction: Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota by Jaunet-Lahary, Titouan, Shimamura, Tatsuro, Hayashi, Masahiro, Nomura, Norimichi, Hirasawa, Kouta, Shimizu, Tetsuya, Yamashita, Masao, Tsutsumi, Naotaka, Suehiro, Yuta, Kojima, Keiichi, Sudo, Yuki, Tamura, Takashi, Iwanari, Hiroko, Hamakubo, Takao, Iwata, So, Okazaki, Kei-ichi, Hirai, Teruhisa, Yamashita, Atsuko

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Detection of acute toxicity of aflatoxin B1 to human hepatocytes in vitro and in vivo using chimeric mice with humanized livers by Ishida, Yuji, Yamasaki, Chihiro, Iwanari, Hiroko, Yamashita, Hisahiko, Ogawa, Yuko, Yanagi, Ami, Furukawa, Suzue, Kojima, Yuha, Chayama, Kazuaki, Kamiie, Junichi, Tateno, Chise

“…Aflatoxin B1 (AFB1), a mycotoxin, is acutely hepatotoxic to many animals including humans. However, there are marked interspecies differences in sensitivity to…”
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Generation of antibodies against membrane proteins by Hamakubo, Takao, Kusano-Arai, Osamu, Iwanari, Hiroko

“…The monoclonal antibody has become an important therapeutic in the treatment of both hematological malignancies and solid tumors. The recent success of…”
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Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95 by Noritake, Jun, Fukata, Yuko, Iwanaga, Tsuyoshi, Hosomi, Naoki, Tsutsumi, Ryouhei, Matsuda, Naoto, Tani, Hideki, Iwanari, Hiroko, Mochizuki, Yasuhiro, Kodama, Tatsuhiko, Matsuura, Yoshiharu, Bredt, David S, Hamakubo, Takao, Fukata, Masaki

“…Protein palmitoylation is the most common posttranslational lipid modification; its reversibility mediates protein shuttling between intracellular…”
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Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota by Jaunet-Lahary, Titouan, Shimamura, Tatsuro, Hayashi, Masahiro, Nomura, Norimichi, Hirasawa, Kouta, Shimizu, Tetsuya, Yamashita, Masao, Tsutsumi, Naotaka, Suehiro, Yuta, Kojima, Keiichi, Sudo, Yuki, Tamura, Takashi, Iwanari, Hiroko, Hamakubo, Takao, Iwata, So, Okazaki, Kei-ichi, Hirai, Teruhisa, Yamashita, Atsuko

“…An oxalate-degrading bacterium in the gut microbiota absorbs food-derived oxalate to use this as a carbon and energy source, thereby reducing the risk of…”
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Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody by Miyanabe, Kazuhiro, Akiba, Hiroki, Kuroda, Daisuke, Nakakido, Makoto, Kusano-Arai, Osamu, Iwanari, Hiroko, Hamakubo, Takao, Caaveiro, Jose M M, Tsumoto, Kouhei

“…Abstract Molecular recognition is a fundamental event at the core of essentially every biological process. In particular, intermolecular H-bonds have been…”
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Phosphatidylinositol 3-Phosphatase Myotubularin-related Protein 6 (MTMR6) Is Regulated by Small GTPase Rab1B in the Early Secretory and Autophagic Pathways by Mochizuki, Yasuhiro, Ohashi, Riuko, Kawamura, Takeshi, Iwanari, Hiroko, Kodama, Tatsuhiko, Naito, Makoto, Hamakubo, Takao

“…A large family of myotubularin phosphatases dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, which are known to…”
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Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function by Chen, Gin-Fu, Sudhahar, Varadarajan, Youn, Seock-Won, Das, Archita, Cho, Jaehyung, Kamiya, Tetsuro, Urao, Norifumi, McKinney, Ronald D., Surenkhuu, Bayasgalan, Hamakubo, Takao, Iwanari, Hiroko, Li, Senlin, Christman, John W., Shantikumar, Saran, Angelini, Gianni D., Emanueli, Costanza, Ushio-Fukai, Masuko, Fukai, Tohru

“…Copper (Cu), an essential micronutrient, plays a fundamental role in inflammation and angiogenesis; however, its precise mechanism remains undefined. Here we…”
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Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen by Yumura, Kyohei, Akiba, Hiroki, Nagatoishi, Satoru, Kusano-Arai, Osamu, Iwanari, Hiroko, Hamakubo, Takao, Tsumoto, Kouhei

“…Bispecific antibody targeting of two different antigens is promising, but when fragment-based antibodies are used, homogeneous production is difficult. To…”
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