Search Results - "IWAMOTO, Takaaki"

High levels of oxidatively generated DNA damage 8,5′-cyclo-2′-deoxyadenosine accumulate in the brain tissues of xeroderma pigmentosum group A gene-knockout mice by Mori, Toshio, Nakane, Hironobu, Iwamoto, Takaaki, Krokidis, Marios G., Chatgilialoglu, Chryssostomos, Tanaka, Kiyoji, Kaidoh, Toshiyuki, Hasegawa, Masatoshi, Sugiura, Shigeki

“…[Display omitted] •Xpa−/− mice accumulate more cyclopurine lesions in the brain tissues than wt mice.•The findings support the hypothesis for the development…”
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Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis by Somekawa, Satoshi, Imagawa, Keiichi, Hayashi, Hisaki, Sakabe, Masahide, Ioka, Tomoko, Sato, Genki E, Inada, Ken, Iwamoto, Takaaki, Mori, Toshio, Uemura, Shiro, Nakagawa, Osamu, Saito, Yoshihiko

“…Members of the transforming growth factor-β superfamily play essential roles in various aspects of embryonic development and physiological organ function…”
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Effect of Prolyl-hydroxyproline (Pro-Hyp), a Food-Derived Collagen Peptide in Human Blood, on Growth of Fibroblasts from Mouse Skin by Shigemura, Yasutaka, Iwai, Koji, Morimatsu, Fumiki, Iwamoto, Takaaki, Mori, Toshio, Oda, Chikako, Taira, Toshio, Park, Eun Young, Nakamura, Yasusi, Sato, Kenji

“…We examined the effect of prolyl-hydroxyproline (Pro-Hyp), which occurs in human peripheral blood after ingestion of collagen peptide, on the migration and…”
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Urinary FSP1 Is a Biomarker of Crescentic GN by IWANO, Masayuki, YAMAGUCHI, Yukinari, IWAMOTO, Takaaki, NAKATANI, Kimihiko, MATSUI, Masaru, KUBO, Atsushi, AKAI, Yasuhiro, MORI, Toshio, SAITO, Yoshihiko

“…Fibroblast-specific protein 1 (FSP1)-expressing cells accumulate in damaged kidneys, but whether urinary FSP1 could serve as a biomarker of active renal injury…”
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Proteolytic fragmentation and sugar chains of plasma ADAMTS13 purified by a conformation-dependent monoclonal antibody by Hiura, Hisahide, Matsui, Taei, Matsumoto, Masanori, Hori, Yuji, Isonishi, Ayami, Kato, Seiji, Iwamoto, Takaaki, Mori, Toshio, Fujimura, Yoshihiro

“…ADAMTS13 is a metalloproteinase that specifically cleaves unusually large von Willbrand factor multimers under high-shear stress. Deficiency of ADAMTS13…”
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Neurons and astrocytes exhibit lower activities of global genome nucleotide excision repair than do fibroblasts by Yamamoto, Aya, Nakamura, Yu, Kobayashi, Nobuhiko, Iwamoto, Takaaki, Yoshioka, Akira, Kuniyasu, Hiroki, Kishimoto, Toshifumi, Mori, Toshio

“…Nucleotide excision repair (NER) is a DNA repair pathway, which eliminates various types of helix-distorting DNA damage including some forms of oxidative…”
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Short half-lives of ataxia-associated aprataxin proteins in neuronal cells by Hirano, Makito, Asai, Hirohide, Kiriyama, Takao, Furiya, Yoshiko, Iwamoto, Takaaki, Nishiwaki, Tomohisa, Yamamoto, Aya, Mori, Toshio, Ueno, Satoshi

“…Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH)/ataxia with oculomotor apraxia type 1 (AOA1) is caused by mutations in the gene…”
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Generation and evaluation of an anti-REV1 monoclonal antibody by Tachibana, Noriko, Iwamoto, Takaaki, Kawamura, Toshiyuki, Masuda, Yuji, Mori, Toshio, Kamiya, Kenji

“…Continuous exposure of cells to exogenous and endogenous agents produces many types of DNA damage during normal cell cycles. Post-replication repair,…”
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Quantitative and in situ Detection of Oxidatively Generated DNA Damage 8,5′-Cyclo-2′-Deoxyadenosine Using an Immunoassay with a Novel Monoclonal Antibody by Iwamoto, Takaaki, Brooks, Philip J., Nishiwaki, Tomohisa, Nishimura, Kazuki, Kobayashi, Nobuhiko, Sugiura, Shigeki, Mori, Toshio

“…Xeroderma pigmentosum (XP) is a genetic disorder associated with defects in nucleotide excision repair, which eliminates a wide variety of helix‐distorting…”
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Protein kinase Cγ, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin by Asai, Hirohide, Hirano, Makito, Shimada, Keiji, Kiriyama, Takao, Furiya, Yoshiko, Ikeda, Masanori, Iwamoto, Takaaki, Mori, Toshio, Nishinaka, Kazuto, Konishi, Noboru, Udaka, Fukashi, Ueno, Satoshi

“…Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant disease caused by mutations in the gene encoding protein kinase Cγ (PKCγ). We report an SCA14…”
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Tmem 100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis by Somekawa, Satoshi, Imagawa, Keiichi, Hayashi, Hisaki, Sakabe, Masahide, Ioka, Tomoko, Sato, Genki E., Inada, Ken, Iwamoto, Takaaki, Mori, Toshio, Uemura, Shiro, Nakagawa, Osamu, Saito, Yoshihiko

“…Members of the transforming growth factor-β superfamily play essential roles in various aspects of embryonic development and physiological organ function…”
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Quantitative detection of 4-hydroxyequilenin-DNA adducts in mammalian cells using an immunoassay with a novel monoclonal antibody by Okahashi, Yumiko, Iwamoto, Takaaki, Suzuki, Naomi, Shibutani, Shinya, Sugiura, Shigeki, Itoh, Shinji, Nishiwaki, Tomohisa, Ueno, Satoshi, Mori, Toshio

“…Estrogen-DNA adducts are potential biomarkers for assessing the risk and development of estrogen-associated cancers. 4-Hydroxyequilenin (4-OHEN) and…”
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Protein kinase C[gamma], a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin by Asai, Hirohide, Hirano, Makito, Shimada, Keiji, Kiriyama, Takao, Furiya, Yoshiko, Ikeda, Masanori, Iwamoto, Takaaki, Mori, Toshio, Nishinaka, Kazuto, Konishi, Noboru, Udaka, Fukashi, Ueno, Satoshi

“…Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant disease caused by mutations in the gene encoding protein kinase Cγ (PKCγ). We report an SCA14…”
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Protein kinase Cg, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin by Asai, Hirohide, Hirano, Makito, Shimada, Keiji, Kiriyama, Takao, Furiya, Yoshiko, Ikeda, Masanori, Iwamoto, Takaaki, Mori, Toshio, Nishinaka, Kazuto, Konishi, Noboru, Udaka, Fukashi, Ueno, Satoshi

“…Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant disease caused by mutations in the gene encoding protein kinase Cg (PKCg). We report an SCA14…”
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Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients by Nishiwaki, Tomohisa, Kobayashi, Nobuhiko, Iwamoto, Takaaki, Yamamoto, Aya, Sugiura, Shigeki, Liu, Yin-Chang, Sarasin, Alain, Okahashi, Yumiko, Hirano, Makito, Ueno, Satoshi, Mori, Toshio

“…To get a clue to understand how mutations in the XPD gene result in different skin cancer susceptibilities in patients with xeroderma pigmentosum (XP) or…”
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