Search Results - "IUBMB life"

Bacterial co‐infections with SARS‐CoV‐2 by Mirzaei, Rasoul, Goodarzi, Pedram, Asadi, Muhammad, Soltani, Ayda, Aljanabi, Hussain ali abraham, Jeda, Ali Salimi, Dashtbin, Shirin, Jalalifar, Saba, Mohammadzadeh, Rokhsareh, Teimoori, Ali, Tari, Kamran, Salari, Mehdi, Ghiasvand, Sima, Kazemi, Sima, Yousefimashouf, Rasoul, Keyvani, Hossein, Karampoor, Sajad

“…The pandemic coronavirus disease 2019 (COVID‐19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2), has affected millions of people…”
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Copper homeostasis: Emerging target for cancer treatment by Li, Yueqin

“…Copper (Cu) is an essential micronutrient involved in a variety of fundamental biological processes. Recently, disorder of Cu homeostasis can be observed in…”
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Iron and ferroptosis: A still ill‐defined liaison by Doll, Sebastian, Conrad, Marcus

“…Ferroptosis is a recently described form of regulated necrotic cell death, which appears to contribute to a number of diseases, such as tissue…”
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Regulatory role of vitamin E in the immune system and inflammation by Lewis, Erin Diane, Meydani, Simin Nikbin, Wu, Dayong

“…Vitamin E, a potent lipid‐soluble antioxidant, found in higher concentration in immune cells compared to other cells in blood, is one of the most effective…”
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The malate–aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway by Borst, Piet

“…This article presents a personal and critical review of the history of the malate–aspartate shuttle (MAS), starting in 1962 and ending in 2020. The MAS was…”
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Ferritin, cellular iron storage and regulation by Arosio, Paolo, Elia, Leonardo, Poli, Maura

“…Ferritin is considered the major iron storage protein which maintains a large iron core in its cavity and has ferroxidase activity. There are many types of…”
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Vitamin E: Regulatory Redox Interactions by Miyazawa, Taiki, Burdeos, Gregor C., Itaya, Mayuko, Nakagawa, Kiyotaka, Miyazawa, Teruo

“…Vitamin E is an essential nutrient that was discovered in the 1920s. Many of the physiological functions of vitamin E, including its antioxidative effects,…”
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Overcoming multidrug resistance in cancer: Recent progress in nanotechnology and new horizons by Majidinia, Maryam, Mirza‐Aghazadeh‐Attari, Mohammad, Rahimi, Mahdi, Mihanfar, Ainaz, Karimian, Ansar, Safa, Amin, Yousefi, Bahman

“…Multidrug resistance (MDR), defined as the ability of cancer cells to gain resistance to both conventional and novel chemotherapy agents, is an important…”
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P53‐dependent induction of ferroptosis is required for artemether to alleviate carbon tetrachloride‐induced liver fibrosis and hepatic stellate cell activation by Wang, Ling, Zhang, Zili, Li, Mengmeng, Wang, Feixia, Jia, Yan, Zhang, Feng, Shao, Jiangjuan, Chen, Anping, Zheng, Shizhong

“…Ferroptosis is recently reported as a new mode of regulated cell death. Its essential characteristics are disturbed redox homeostasis, overloaded iron, and…”
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The glutathione cycle: Glutathione metabolism beyond the γ‐glutamyl cycle by Bachhawat, Anand Kumar, Yadav, Shambhu

“…Glutathione was discovered in 1888, over 125 years ago. Since then, our understanding of various functions and metabolism of this important molecule has grown…”
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RNA sensors of the innate immune system and their detection of pathogens by Chen, Nanhua, Xia, Pengpeng, Li, Shuangjie, Zhang, Tangjie, Wang, Tony T., Zhu, Jianzhong

“…Summary The innate immune system plays a critical role in pathogen recognition and initiation of protective immune response through the recognition of pathogen…”
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Biological activity of selenium: Revisited by Wrobel, Jagoda K., Power, Ronan, Toborek, Michal

“…Selenium (Se) is an essential micronutrient that exerts multiple and complex effects on human health. Se is essential for human well‐being largely due to its…”
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Lactate dehydrogenase a in cancer: A promising target for diagnosis and therapy by Miao, Ping, Sheng, Shile, Sun, Xiaoguang, Liu, Jianjun, Huang, Gang

“…One of the principal biochemical characteristics of malignant cells compared to normal cells is a metabolic switch from oxidative phosphorylation to increased…”
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Iron overload‐induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study by Jiang, Zengxin, Wang, Hao, Qi, Guobin, Jiang, Chang, Chen, Kangning, Yan, Zuoqin

“…Growing evidence indicates that iron overload is an independent risk factor for osteoporosis. However, the mechanisms are not fully understood. The purpose of…”
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Toll‐like receptors in neuroinflammation, neurodegeneration, and alcohol‐induced brain damage by Pascual, María, Calvo‐Rodriguez, Maria, Núñez, Lucía, Villalobos, Carlos, Ureña, Juan, Guerri, Consuelo

“…Toll‐like receptors (TLRs) or pattern recognition receptors respond to pathogen‐associated molecular patterns (PAMPs) or internal damage‐associated molecular…”
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Glucose‐6‐phosphate dehydrogenase, NADPH, and cell survival by Stanton, Robert C.

“…Glucose‐6‐phosphate dehydrogenase (G6PD) is the rate‐limiting enzyme of the pentose phosphate pathway. Many scientists think that the roles and regulation of…”
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Significance of l‐carnitine for human health by Adeva‐Andany, María M., Calvo‐Castro, Isabel, Fernández‐Fernández, Carlos, Donapetry‐García, Cristóbal, Pedre‐Piñeiro, Ana María

“…Carnitine acyltransferases catalyze the reversible transfer of acyl groups from acyl‐coenzyme A esters to l‐carnitine, forming acyl‐carnitine esters that may…”
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The monocarboxylate transporter family—Role and regulation by Halestrap, Andrew P., Wilson, Marieangela C.

“…Monocarboxylate transporter (MCT) isoforms 1–4 catalyze the proton‐linked transport of monocarboxylates such as L‐lactate across the plasma membrane, whereas…”
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Ketone bodies mimic the life span extending properties of caloric restriction by Veech, Richard L., Bradshaw, Patrick C., Clarke, Kieran, Curtis, William, Pawlosky, Robert, King, M. Todd

“…The extension of life span by caloric restriction has been studied across species from yeast and Caenorhabditis elegans to primates. No generally accepted…”
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Apolipoprotein E isoforms and lipoprotein metabolism by Phillips, Michael C.

“…Apolipoprotein (apo) E is a 299‐residue protein which functions as a key regulator of plasma lipid levels. Human apoE exists as three common isoforms and the…”
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