Search Results - "ITO, Yasushi"

RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease by Ofengeim, Dimitry, Mazzitelli, Sonia, Ito, Yasushi, DeWitt, Judy Park, Mifflin, Lauren, Zou, Chengyu, Das, Sudeshna, Adiconis, Xian, Chen, Hongbo, Zhu, Hong, Kelliher, Michelle A., Levin, Joshua Z., Yuan, Junying

“…Dysfunction of microglia is known to play an important role in Alzheimer’s disease (AD). Here, we investigated the role of RIPK1 in microglia mediating the…”
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Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis by Geng, Jiefei, Ito, Yasushi, Shi, Linyu, Amin, Palak, Chu, Jiachen, Ouchida, Amanda Tomie, Mookhtiar, Adnan Kasim, Zhao, Heng, Xu, Daichao, Shan, Bing, Najafov, Ayaz, Gao, Guangping, Akira, Shizuo, Yuan, Junying

“…Stimulation of TNFR1 by TNFα can promote three distinct alternative mechanisms of cell death: necroptosis, RIPK1-independent and -dependent apoptosis. How…”
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RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS by Ito, Yasushi, Ofengeim, Dimitry, Najafov, Ayaz, Das, Sudeshna, Saberi, Shahram, Li, Ying, Hitomi, Junichi, Zhu, Hong, Chen, Hongbo, Mayo, Lior, Geng, Jiefei, Amin, Palak, DeWitt, Judy Park, Mookhtiar, Adnan Kasim, Florez, Marcus, Ouchida, Amanda Tomie, Fan, Jian-bing, Pasparakis, Manolis, Kelliher, Michelle A., Ravits, John, Yuan, Junying

“…Mutations in the optineurin (OPTN) gene have been implicated in both familial and sporadic amyotrophic lateral sclerosis (ALS). However, the role of this…”
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Activation of Necroptosis in Multiple Sclerosis by Ofengeim, Dimitry, Ito, Yasushi, Najafov, Ayaz, Zhang, Yaoyang, Shan, Bing, DeWitt, Judy Park, Ye, Juanying, Zhang, Xumin, Chang, Ansi, Vakifahmetoglu-Norberg, Helin, Geng, Jiefei, Py, Benedicte, Zhou, Wen, Amin, Palak, Lima, Jonilson Berlink, Qi, Chunting, Yu, Qiang, Trapp, Bruce, Yuan, Junying

“…Multiple sclerosis (MS), a common neurodegenerative disease of the CNS, is characterized by the loss of oligodendrocytes and demyelination. Tumor necrosis…”
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Air inflow into vacuum-type immobilization devices impacts setup errors by Matsubayashi, Fumiyasu, Kamima, Tatsuya, Ito, Yasushi, Yoshioka, Yasuo

“…We aimed to determine the impact of air inflow into vacuum-type immobilization devices (VIDs) on setup errors. We assigned 70 patients undergoing radiotherapy…”
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The role of molecular analysis of SLC2A1 in the diagnostic workup of glucose transporter 1 deficiency syndrome by Takahashi, Satoru, Tanaka, Ryosuke, Takeguchi, Ryo, Kuroda, Mami, Akaba, Yuichi, Ito, Yasushi

“…The study aimed to investigate the role of molecular analysis of SLC2A1 in the diagnostic workup of glucose transporter 1 deficiency syndrome (Glut1DS). During…”
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Octree-based reasonable-quality hexahedral mesh generation using a new set of refinement templates by Ito, Yasushi, Shih, Alan M., Soni, Bharat K.

“…An octree‐based mesh generation method is proposed to create reasonable‐quality, geometry‐adapted unstructured hexahedral meshes automatically from…”
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Outcome of ketogenic diets in GLUT1 deficiency syndrome in Japan: A nationwide survey by Fujii, Tatsuya, Ito, Yasushi, Takahashi, Satoru, Shimono, Kuriko, Natsume, Jun, Yanagihara, Keiko, Oguni, Hirokazu

“…Abstract Objectives To evaluate the outcome of ketogenic diets (KDs) in patients with glucose transport type 1 deficiency syndrome (GLUT1DS) in Japan. Methods…”
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The Impacts of Mindfulness-Based Stress Reduction (MBSR) on Mindfulness and Well-being for Regular and Novice Meditators by Ito, Yasushi, Browne, Cheryl A., Yamamoto, Kazumi

“…Objectives As mindfulness practices become mainstream, it is increasingly common for participants in mindfulness-based interventions (MBI) to have previous…”
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Nationwide survey of glucose transporter-1 deficiency syndrome (GLUT-1DS) in Japan by Ito, Yasushi, Takahashi, Satoru, Kagitani-Shimono, Kuriko, Natsume, Jun, Yanagihara, Keiko, Fujii, Tatsuya, Oguni, Hirokazu

“…Abstract Objectives We conducted a nationwide survey of glucose transporter type-1 deficiency syndrome (GLUT-1DS) in Japan in order to clarify its incidence as…”
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Safety and efficacy of verinurad, a selective URAT1 inhibitor, for the treatment of patients with gout and/or asymptomatic hyperuricemia in the United States and Japan: Findings from two phase II trials by Fitz-Patrick, David, Roberson, Kent, Niwa, Kiyoshi, Fujimura, Takabumi, Mori, Koji, Hall, Jesse, Yan, Xiaohong, Shen, Zancong, Liu, Sha, Ito, Yasushi, Baumgartner, Scott

“…Objective: Evaluate efficacy/safety of verinurad monotherapy in patients with gout (Japan/US) or asymptomatic hyperuricemia (Japan). Methods: Two randomized,…”
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Construction of Climate Change-Adapted Seaweed Beds on the Japanese Coast by Miura, Hiroshi, Ito, Yasushi, Suenaga, Yoshihiro

“…Miura, H.; Ito, Y., and Suenaga, Y., 2018. Construction of Climate Change-Adapted Seaweed Beds on the Japanese Coast. In: Shim, J.-S.; Chun, I., and Lim, H.S…”
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Balloon-assisted Onyx Embolization in the Management of Complicated Dural Arterioevenous Fistula by Kurabe, Satoshi, Ito, Yasushi, Kumagai, Takashi

“…Objective: Dural arteriovenous fistula (dAVF) is an abnormal vascular communication between the meningeal artery and vein at the dura mater, with frequent…”
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Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice by Ito, Yasushi, Yamada, Mitsunori, Tanaka, Hirotaka, Aida, Kazunari, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Hozumi, Isao, Inuzuka, Takashi, Takahashi, Hitoshi, Hara, Hideaki

“…Abstract Endoplasmic reticulum (ER) stress-induced neuronal death may play a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS). However,…”
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Computational Fluid Dynamic Analysis of the Posterior Airway Space After Maxillomandibular Advancement for Obstructive Sleep Apnea Syndrome by Sittitavornwong, Somsak, DDS, DMD, MS, Waite, Peter D., MPH, DDS, MD, Shih, Alan M., PhD, Cheng, Gary C., PhD, Koomullil, Roy, PhD, Ito, Yasushi, PhD, Cure, Joel K., MD, Harding, Susan M., MD, Litaker, Mark, PhD

“…Purpose This study evaluated the soft tissue change of the upper airway after maxillomandibular advancement (MMA) using computational fluid dynamics. Materials…”
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Establishment of a flow cytometry screening method for patients with glucose transporter 1 deficiency syndrome by Nakamura, Sachie, Ito, Yasushi, Hayakawa, Hiroko, Aoki, Shiho, Yamagata, Takanori, Osaka, Hitoshi

“…We assessed the usefulness of flow cytometry as a functional assay to measure glucose transporter 1 (GLUT1) levels on the surface of red blood cells (RBCs)…”
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A phosphor sheet and a backlight system providing wider color gamut for LCDs by Ito, Yasushi, Hori, Tomomitsu, Kusunoki, Tsuneo, Nomura, Hiroshi, Kondo, Hirofumi

“…SrGa2S4:Eu and CaS:Eu phosphors are useful to provide a wider color gamut to LCDs since their emissions are narrower, but they easily react with moisture. The…”
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Clinical characteristics of arteriovenous malformations in the cerebellopontine angle cistern by Nishino, Kazuhiko, Hasegawa, Hitoshi, Morita, Kenichi, Fukuda, Masafumi, Ito, Yasushi, Fujii, Yukihiko, Sato, Mitsuya

“…OBJECTIVE Arteriovenous malformations (AVMs) in the cerebellopontine angle cistern (CPAC) are specific lesions that can cause neurovascular compression…”
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Role of RhoA Inactivation in Reduced Cell Proliferation of Human Airway Smooth Muscle by Simvastatin by Takeda, Naoya, Kondo, Masashi, Ito, Satoru, Ito, Yasushi, Shimokata, Kaoru, Kume, Hiroaki

“…Enhanced proliferation of smooth muscle cells contributes to airway remodeling of bronchial asthma. Recently, statins, inhibitors of…”
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Preoperative concurrent endocrine therapy with chemotherapy in luminal B-like breast cancer by Matsunuma, Ryoichi, Watanabe, Toru, Hozumi, Yasuo, Koizumi, Kei, Ito, Yasushi, Maruyama, Shoko, Ogura, Hiroyuki, Goto, Keigo, Mori, Hiroki, Sawai, Noriko, Shiiya, Norihiko

“…Purpose Luminal B-like breast cancer is sensitive to both chemotherapy and endocrine therapy. We aimed to assess the safety and efficacy of concomitant…”
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