Search Results - "ITALIA, J. L"
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PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral
Published in Journal of controlled release (01-06-2007)“…The cyclosporine-loaded poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) were prepared by the emulsion–diffusion–evaporation method and were optimized for…”
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Biodegradable Nanoparticles Improve Oral Bioavailability of Amphotericin B and Show Reduced Nephrotoxicity Compared to Intravenous Fungizone
Published in Pharmaceutical research (01-06-2009)“…Purpose Amphotericin B (AMB), an effective antifungal and antileishmanial agent associated with low oral bioavailability (0.3%) and severe nephrotoxicity, was…”
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Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine a-induced nephrotoxicity in rats
Published in Pharmaceutical research (01-05-2007)“…Ellagic acid (EA), a dietary antioxidant associated with poor biopharmaceutical properties, was encapsulated into poly(lactide-co-glycolide) (PLGA) and…”
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The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection
Published in Journal of controlled release (28-06-2012)“…Amphotericin B (AMB) is used to treat both fungal and leishmanial infections, which are of major significance to human health. Clinical use of free AMB is…”
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Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: Evaluation of their antioxidant potential against cyclosporine induced nephrotoxicity in rats
Published in Journal of controlled release (12-03-2007)“…Ellagic acid (EA) is a potent antioxidant marketed as a nutritional supplement. Its pharmacological activity has been reported in wide variety of disease…”
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High-performance liquid chromatographic analysis of amphotericin B in rat plasma using α-naphthol as an internal standard
Published in Analytica chimica acta (16-02-2009)“…A simple, sensitive and accurate reverse phase high-performance liquid chromatographic (RP-HPLC) method with photo-diode array detector (PDA) was developed and…”
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Evaluating the potential of polyester nanoparticles for per oral delivery of amphotericin B in treating visceral leishmaniasis
Published in Journal of biomedical nanotechnology (01-08-2012)“…Leishmaniasis is a protozoan disease, which is responsible for response for major epidemics in many parts of the World. Amphotericin B (AMB) is one of the…”
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Disease, destination, dose and delivery aspects of ciclosporin: the state of the art
Published in Drug discovery today (01-09-2006)“…Since its discovery in 1971, ciclosporin has revolutionized organ transplantation and the treatment of autoimmune disorders. The wide array of applications…”
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High-performance liquid chromatographic analysis of amphotericin B in rat plasma using a-naphthol as an internal standard
Published in Analytica chimica acta (16-02-2009)“…A simple, sensitive and accurate reverse phase high-performance liquid chromatographic (RP-HPLC) method with photo-diode array detector (PDA) was developed and…”
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10
Differential Expression of Angiotensin-converting Enzyme and Chymase in Dogs with Chronic Mitral Regurgitation
Published in Journal of molecular and cellular cardiology (01-05-1999)“…The current study tested the hypothesis that angiotensin-converting enzyme (ACE) and chymase expression are subject to different regulatory processes in the…”
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Use of beta-blockers in older adults with chronic heart failure
Published in The American journal of the medical sciences (01-08-2004)“…Most heart failure patients are older adults. Angiotensin-converting enzyme (ACE) inhibitors reduce mortality and morbidity in patients with systolic heart…”
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Validation of attenuation-corrected equilibrium radionuclide angiographic determinations of right ventricular volume: comparison with cast-validated biplane cineventriculography
Published in Circulation (New York, N.Y.) (01-08-1985)“…To determine the accuracy of attenuation-corrected equilibrium radionuclide angiographic determinations of right ventricular volumes, we initially studied 14…”
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