Search Results - "ISTURIZ, M"

The oxidative stress induced in vivo by Shiga toxin‐2 contributes to the pathogenicity of haemolytic uraemic syndrome by Gomez, S. A., Abrey‐Recalde, M. J., Panek, C. A., Ferrarotti, N. F., Repetto, M. G., Mejías, M. P., Fernández, G. C., Vanzulli, S., Isturiz, M. A., Palermo, M. S.

“…Summary Typical haemolytic uraemic syndrome (HUS) is caused by Shiga toxin (Stx)‐producing Escherichia coli infections and is characterized by thrombotic…”
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Tolerance to lipopolysaccharide promotes an enhanced neutrophil extracellular traps formation leading to a more efficient bacterial clearance in mice by Landoni, V. I., Chiarella, P., Martire‐Greco, D., Schierloh, P., van‐Rooijen, N., Rearte, B., Palermo, M. S., Isturiz, M. A., Fernández, G. C.

“…Summary Tolerance to lipopolysaccharide (LPS) constitutes a stress adaptation, in which a primary contact with LPS results in a minimal response when a second…”
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Mifepristone (RU486) restores humoral and T cell‐mediated immune response in endotoxin immunosuppressed mice by Rearte, B, Maglioco, A, Balboa, L, Bruzzo, J, Landoni, V.I, Laborde, E.A, Chiarella, P, Ruggiero, R.A, Fernández, G.C, Isturiz, M.A

“…Sepsis and septic shock can be caused by Gram‐positive and ‐negative bacteria and other microorganisms. In the case of Gram‐negative bacteria, endotoxin, a…”
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Differential effects of glucocorticoids in the establishment and maintenance of endotoxin tolerance by Rearte, B, Landoni, V, Laborde, E, Fernández, G, Isturiz, M

“…Gram-negative infections can result in endotoxic shock, which is the most common cause of death in intensive care units. Most of the undesirable effects in…”
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Relevance of neutrophils in the murine model of haemolytic uraemic syndrome: mechanisms involved in Shiga toxin type 2‐induced neutrophilia by Fernandez, G. C., Lopez, M. F., Gomez, S. A., Ramos, M. V., Bentancor, L. V., Fernandez‐Brando, R. J., Landoni, V. I., Dran, G. I., Meiss, R., Isturiz, M. A., Palermo, M. S.

“…Summary It has been demonstrated that infections due to Shiga toxins (Stx) producing Escherichia coli are the main cause of the haemolytic uraemic syndrome…”
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Fibrinogen Promotes Neutrophil Activation and Delays Apoptosis by Rubel, Carolina, Fernandez, Gabriela C, Dran, Graciela, Bompadre, Macarena Beigier, Isturiz, Martin A, Palermo, Marina S

“…The acute phase of the inflammatory response involves an increase in the concentrations of different plasma proteins that include fibrinogen (Fbg) and multiple…”
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Interleukin‐1β induces in vivo tolerance to lipopolysaccharide in mice by ALVES‐ROSA, F., VULCANO, M., BEIGIER‐BOMPADRE, M., FERNÁNDEZ, G., PALERMO, M., ISTURIZ, M. A.

“…SUMMARY Endotoxin or lipopolysaccharide (LPS) tolerance may be partially due to the secretion of potent anti‐inflammatory cytokines following severe…”
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Endogenous glucocorticoids modulate neutrophil function in a murine model of haemolytic uraemic syndrome by Gómez, S. A., Fernández, G. C., Camerano, G., Dran, G., Rosa, F. A., Barrionuevo, P., Isturiz, M. A., Palermo, M. S.

“…Summary Haemolytic uraemic syndrome (HUS) is caused by Shiga‐toxin‐producing Escherichia coli (STEC). Although, Shiga toxin type 2 (Stx2) is responsible for…”
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Endogenous glucocorticoids attenuate Shiga toxin‐2‐induced toxicity in a mouse model of haemolytic uraemic syndrome by GÓMEZ, S. A., FERNÁNDEZ, G. C., VANZULLI, S., DRAN, G., RUBEL, C., BERKI, T., ISTURIZ, M. A., PALERMO, M. S.

“…SUMMARY The concept that during an immune challenge the release of glucocorticoids (GC) provides feedback inhibition on evolving immune responses has been…”
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Immune complex–FcγR interaction modulates monocyte/macrophage molecules involved in inflammation and immune response by BARRIONUEVO, P., BEIGIER‐BOMPADRE, M., FERNANDEZ, G. C., GOMEZ, S., ALVES‐ROSA, M. F., PALERMO, M. S., ISTURIZ, M. A.

“…SUMMARY The interaction between receptors for the Fc portion of IgG (FcγRs) from monocytes/macrophages and immune complexes (IC) triggers regulatory and…”
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Pretreatment of mice with lipopolysaccharide (LPS) or IL‐1β exerts dose‐dependent opposite effects on Shiga toxin‐2 lethality by Palermo, M., Alves‐Rosa, F., Rubel, C., Fernández, G. C., Fernández‐Alonso, G., Alberto, F., Rivas, M., Isturiz, M.

“…Haemolytic uraemic syndrome (HUS) has been closely associated with infection with a group of Shiga toxin‐producing enterohaemorrhagic Eschericchia coli in…”
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Depletion of liver and splenic macrophages reduces the lethality of Shiga toxin‐2 in a mouse model by PALERMO, M. S, ALVES ROSA, M. F, VAN ROOIJEN, N, ISTURIZ, M. A

“…The haemolytic uraemic syndrome (HUS) is a clinical syndrome consisting of haemolytic anaemia, thrombocytopenia, and acute renal insufficiency. HUS is the most…”
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Shiga Toxin-2 Induces Neutrophilia and Neutrophil Activation in a Murine Model of Hemolytic Uremic Syndrome by Fernández, Gabriela C., Rubel, Carolina, Dran, Graciela, Gómez, Sonia, Isturiz, Martı́n A., Palermo, Marina S.

“…It has been demonstrated that infections due to Shiga toxins (Stx) producing Escherichia coli are the main cause of the hemolytic uremic syndrome (HUS)…”
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Immune complexes (IC) down‐regulate the basal and interferon‐γ‐induced expression of MHC Class II on human monocytes by Barrionuevo, P., Beigier‐Bompadre, M., De La Barrera, S., Alves‐Rosa, M. F., Fernandez, G., Palermo, M. S., Isturiz, M. A.

“…The interaction of Fc receptors for IgG (FcγRs) on monocytes/macrophages with immune complexes (IC) triggers regulatory and effector functions. Previous…”
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Monocytes and neutrophils from tuberculosis patients are insensitive to anti‐inflammatory effects triggered by the prototypic formyl peptide N‐formyl‐methionyl‐leucyl‐phenylalanine (FMLP) by BEIGIER‐BOMPADRE, M., ALEMÁN, M., BARRIONUEVO, P., FRANCO, M. C., RUBEL, C. J., SASIAIN, M. DEL C., PALERMO, M. S., ABBATE, E., ISTURIZ, M. A.

“…SUMMARY Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis where formyl peptides, which are cleavage products of bacterial and…”
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N‐formyl‐methionyl‐leucyl‐phenylalanine (fMLP) inhibits tumour necrosis factor‐alpha (TNF‐α) production on lipopolysaccharide (LPS)‐stimulated human neutrophils by Vulcano, M., Rosa, M. F. Alves, Minnucci, F. S., Cherñavsky, A. C., Isturiz, M. A.

“…During Gram‐negative infections bacterial components, such as LPS and formylated peptides, exert profound physiological effects on polymorphonuclear…”
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Inhibition of allospecific response in pancreatic islet transplantation: The glycan approach by Vieiro, M., Ceballos, C., Barrionuevo, P., Hyon, S.H., Isturiz, M., Argibay, P.

“…Host resistance has precluded clinical islet transplantation from becoming a consistent therapy for type I diabetic patients, mainly due to both specific and…”
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Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune thrombocytopenic purpura in a mouse model by Alves-Rosa, Fernanda, Stanganelli, Carmen, Cabrera, Juana, van Rooijen, Nico, Palermo, Marina S., Isturiz, Martı́n A.

“…Immune thrombocytopenic purpura (ITP) is an autoimmune disease related to the presence of elevated levels of platelet-associated immunoglobulin, or…”
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Macrophage derived signalling regulates negatively the megakaryocyte compartment by Landoni, V I, Vermeulen, M, Van Rooijen, N, Gómez, S, Palermo, M, Isturiz, M A, Alves-Rosa, F

“…Megakaryocytopoiesis is the process by which stem cells go through a process of commitment, proliferation and differentiation leading to the production of…”
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Deferoxamine reduces tissue injury and lethality in LPS-treated mice by Vulcano, Marisa, Meiss, Roberto P., Isturiz, Martı́n A.

“…We studied the effect of deferoxamine (DFX), an iron chelator, which can also act as a free radical scavenger, in an experimental murine model of sepsis. In…”
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