Search Results - "ISMAIL, Nahed"

Developing RT-LAMP assays for rapid diagnosis of SARS-CoV-2 in saliva by Huang, Xin, Tang, Gongyu, Ismail, Nahed, Wang, Xiaowei

“…The coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has killed millions of people worldwide. The current crisis has created an unprecedented demand…”
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Evasion of host antioxidative response via disruption of NRF2 signaling in fatal Ehrlichia-induced liver injury by Sharma, Aditya Kumar, El Andaloussi, Abdeljabar, Ismail, Nahed

“…Ehrlichia is Gram negative obligate intracellular bacterium that cause human monocytotropic ehrlichiosis (HME). HME is characterized by acute liver damage and…”
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Non-Canonical Inflammasome Pathway: The Role of Cell Death and Inflammation in Ehrlichiosis by Sharma, Aditya Kumar, Ismail, Nahed

“…Activating inflammatory caspases and releasing pro-inflammatory mediators are two essential functions of inflammasomes which are triggered in response to…”
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Gut and genital tract microbiomes: Dysbiosis and link to gynecological disorders by Elkafas, Hoda, Walls, Melinique, Al-Hendy, Ayman, Ismail, Nahed

“…Every year, millions of women are affected by genital tract disorders, such as bacterial vaginosis (BV), endometrial cancer, polycystic ovary syndrome (PCOS),…”
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Label-free SARS-CoV-2 detection and classification using phase imaging with computational specificity by Goswami, Neha, He, Yuchen R., Deng, Yu-Heng, Oh, Chamteut, Sobh, Nahil, Valera, Enrique, Bashir, Rashid, Ismail, Nahed, Kong, Hyunjoon, Nguyen, Thanh H., Best-Popescu, Catherine, Popescu, Gabriel

“…Efforts to mitigate the COVID-19 crisis revealed that fast, accurate, and scalable testing is crucial for curbing the current impact and that of future…”
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Role of Autophagy in Ehrlichia -Induced Liver Injury by Sharma, Aditya Kumar, Ismail, Nahed

“…Autophagy is a cellular process that involves the cell breakdown and recycling of cellular components, such as old, damaged, or abnormal proteins, for…”
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Human Mesenchymal Stem Cells Partially Reverse Infertility in Chemotherapy-Induced Ovarian Failure by Mohamed, Sara A, Shalaby, Shahinaz M, Abdelaziz, Mohamed, Brakta, Soumia, Hill, William D, Ismail, Nahed, Al-Hendy, Ayman

“…Chemotherapy is the most commonly used modality to treat human cancers; however, in many cases it causes irreversible ovarian failure. In this work, we plan to…”
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Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens by Parker, Erica N., Drown, Bryon S., Geddes, Emily J., Lee, Hyang Yeon, Ismail, Nahed, Lau, Gee W., Hergenrother, Paul J.

“…Gram-negative bacterial infections are a significant public health concern, and the lack of new drug classes for these pathogens is linked to the inability of…”
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NK Cell-Mediated Regulation of Protective Memory Responses against Intracellular Ehrlichial Pathogens by Habib, Samar, El Andaloussi, Abdeljabar, Hisham, Ahmed, Ismail, Nahed

“…Ehrlichiae are gram-negative obligate intracellular bacteria that cause potentially fatal human monocytic ehrlichiosis. We previously showed that natural…”
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Epigenetic Modulation of Inflammatory Pathways in Myometrial Stem Cells and Risk of Uterine Fibroids by Yang, Qiwei, Ali, Mohamed, Treviño, Lindsey S, Mas, Aymara, Ismail, Nahed, Al-Hendy, Ayman

“…The period during which tissue and organ development occurs is particularly vulnerable to the influence of environmental exposures. However, the specific…”
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Effect of some freshwater cyanobacteria on Oreochromis niloticus (L.) fish and water quality in Egyptian aquaculture ponds by Saleh, Hassnaa A., Sayed, Sara S.M., El-Gamal, Manal A.H., Ismail, Nahed M. M.

“…The present study aims to evaluate the potential effects of cyanobacteria on water quality parameters and Oreochromis niloticus in the fish ponds at Al-Abbassa…”
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miRNAs: possible regulators of toll like receptors and inflammatory tumor microenvironment in colorectal cancer by Matboli, Marwa, Hossam, Nourhan, Farag, Doaa, Hassan, Mohamed, Shehata, Hanan, Aboelhussein, Marwa, Ismail, Nahed, Eissa, Sanaa

“…Colorectal cancer (CRC) is ranked as the third most commonly diagnosed cancer and the third cause of cancer related deaths. CRC is greatly attributed to…”
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Neutrophils Mediate Immunopathology and Negatively Regulate Protective Immune Responses during Fatal Bacterial Infection-Induced Toxic Shock by Yang, Qin, Ghose, Purnima, Ismail, Nahed

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Human Ehrlichiosis and Anaplasmosis by Ismail, Nahed, MD, PhD, Bloch, Karen C., MD, MPH, McBride, Jere W., PhD

“…Human ehrlichiosis and anaplasmosis are acute febrile tick-borne diseases caused by various members of the genera Ehrlichia and Anaplasma (Anaplasmataceae)…”
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Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10 by Chugh, Rishi Man, Park, Hang-Soo, El Andaloussi, Abdeljabar, Elsharoud, Amro, Esfandyari, Sahar, Ulin, Mara, Bakir, Lale, Aboalsoud, Alshimaa, Ali, Mohamed, Ashour, Dalia, Igboeli, Prosper, Ismail, Nahed, McAllister, Jan, Al-Hendy, Ayman

“…Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in reproductive-age women. Excessive inflammation and elevated androgen…”
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MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock by Kader, Muhamuda, Alaoui-El-Azher, Mounia, Vorhauer, Jennie, Kode, Bhushan B, Wells, Jakob Z, Stolz, Donna, Michalopoulos, George, Wells, Alan, Scott, Melanie, Ismail, Nahed

“…Severe hepatic inflammation is a common cause of acute liver injury following systemic infection with Ehrlichia, obligate Gram-negative intracellular bacteria…”
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Hepatocyte-specific regulation of autophagy and inflammasome activation via MyD88 during lethal Ehrlichia infection by Teymournejad, Omid, Sharma, Aditya Kumar, Abdelwahed, Mohammed, Kader, Muhamuda, Ahmed, Ibrahim, Elkafas, Hoda, Ismail, Nahed

“…Hepatocytes play a crucial role in host response to infection. is an obligate intracellular bacterium that causes potentially life-threatening human monocytic…”
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Protective Immunity and Immunopathology in Ehrlichiosis by Ismail, Nahed, Sharma, Aditya, Soong, Lynn, Walker, David H.

“…Human monocytic ehrlichiosis, a tick transmitted infection, ranges in severity from apparently subclinical to fatal toxic shock-like disease. Models in…”
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Rickettsia australis Activates Inflammasome in Human and Murine Macrophages by Smalley, Claire, Bechelli, Jeremy, Rockx-Brouwer, Dedeke, Saito, Tais, Azar, Sasha R, Ismail, Nahed, Walker, David H, Fang, Rong

“…Rickettsiae actively escape from vacuoles and replicate free in the cytoplasm of host cells, where inflammasomes survey the invading pathogens. In the present…”
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TLR2 and Nod2 mediate resistance or susceptibility to fatal intracellular Ehrlichia infection in murine models of ehrlichiosis by Chattoraj, Partho, Yang, Qin, Khandai, Ankita, Al-Hendy, Omar, Ismail, Nahed

“…Our murine models of human monocytic ehrlichiosis (HME) have shown that severe and fatal ehrlichiosis is due to generation of pathogenic T cell responses…”
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