Search Results - "ISHIBASHI, Masami"
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Screening study of cancer-related cellular signals from microbial natural products
Published in Journal of antibiotics (01-10-2021)“…To identify bioactive natural products from various natural resources, such as plants and microorganisms, we investigated programs to screen for compounds that…”
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Screening for natural products that affect Wnt signaling activity
Published in Journal of natural medicines (01-09-2019)“…Wnt signaling has been implicated in numerous aspects of development, cell biology, and physiology. When aberrantly activated, Wnt signaling can also lead to…”
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Correction to: Screening for natural products that affect Wnt signaling activity
Published in Journal of natural medicines (01-09-2019)“…The article Screening for natural products that affect Wnt signaling activity, written by Masami Ishibashi, was originally published electronically on the…”
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A new 1,2-diketone physalin isolated from Physalis minima and TRAIL-resistance overcoming activity of physalins
Published in Journal of natural medicines (01-03-2023)“…A new 1,2-diketone physalin, physalin XII ( 1 ), and 13 known compounds were isolated from the methanol extract of Physalis minima whole plant collected in…”
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Isolation of Various Flavonoids with TRAIL Resistance-Overcoming Activity from Blumea lacera
Published in Molecules (Basel, Switzerland) (28-12-2022)“…Eighteen compounds, including fourteen flavonoids ( - ), one steroid ( ), two fatty acids ( , ), and one nitrogen-containing compound ( ), were isolated from…”
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Two Bioactive Compounds, Uniformides A and B, Isolated from a Culture of Nocardia uniformis IFM0856T in the Presence of Animal Cells
Published in Organic letters (15-07-2022)“…Two new peptides named uniformides A and B (1 and 2, respectively) were isolated from the cultured extracts of Nocardia uniformis IFM0856T in the presence of…”
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Isolation of nocobactin NAs as Notch signal inhibitors from Nocardia farcinica, a possibility of invasive evolution
Published in Journal of antibiotics (01-04-2021)“…Notch signaling inhibitors with the potential of immune suppressor production by pathogenic bacteria for easy host infection were searched from extracts of…”
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Bio-active Natural Products with TRAIL-Resistance Overcoming Activity
Published in Chemical & pharmaceutical bulletin (01-02-2016)“…Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) has emerged as a promising anticancer agent as it selectively kills cancer cells. However,…”
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Elmenols C-H, new angucycline derivatives isolated from a culture of Streptomyces sp. IFM 11490
Published in Journal of antibiotics (01-05-2017)“…Chemical investigations of the ethyl acetate extract of Streptomyces sp. IFM 11490 have led to the isolation of six new angucycline metabolites, named elmenols…”
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Thannilignan glucoside and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative, two new compounds isolated from Terminalia bellirica
Published in Journal of natural medicines (01-03-2022)“…Two new compounds, thannilignan 9- O -β-glucoside ( 1 ) and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative ( 2 ), and seven known compounds were isolated…”
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Evaluation of Naturally Occurring HIF‐1 Inhibitors for Pulmonary Arterial Hypertension
Published in Chembiochem : a European journal of chemical biology (14-09-2021)“…Pulmonary arterial hypertension (PAH) is a rare and severe progressive disorder characterized by high pulmonary artery pressure. Chronic hypoxia causes a…”
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Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis
Published in Medicinal research reviews (01-09-2008)“…Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) induces apoptosis in many transformed cells but not in normal cells and, hence, has been…”
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Isolation of Ikahonone, 4-Methyl-2,4-dihydroxy-3-pentanone from Bacillus cereus IFM12235
Published in Heterocycles (2022)Get full text
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New biflavonoids isolated from Xylia kerrii leaves extract with selective cytotoxicity against MH7A human rheumatoid arthritis synovial fibroblast cells
Published in Journal of natural medicines (01-06-2024)“…Three new biflavonoids ( 1 – 3 ) and two known flavonoids ( 4 , 5 ) were isolated from Xylia kerrii collected in Thailand. Compounds 1 – 5 showed selective…”
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Isolation of two new trichorzin PA derivatives, trichorzin PA X and XI, from the terrestrial fungus Trichoderma harzianum IFM 66736
Published in Tetrahedron letters (17-05-2023)“…[Display omitted] Two new octadeca-peptibols, trichorzin PA X and XI (1 and 2), were isolated from the fungus Trichoderma harzianum IFM 66736, which was…”
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天然物に学ぶ:Nocardia属放線菌成分
Published in YAKUGAKU ZASSHI (01-01-2024)“…「1. はじめに」天然物探索研究を展開・強化するためには, 天然物資源の収集, 調査, 開拓を継続して行う必要がある. われわれのグループでは, これまでに変形菌, 放線菌, タイ・バングラデシュ産植物等を対象として生物活性スクリーニング研究を行ってきた…”
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Total synthesis of lindbladione, a Hes1 dimerization inhibitor and neural stem cell activator isolated from Lindbladia tubulina
Published in Scientific reports (08-12-2020)“…Lindbladione ( 1 ) is a neural stem cell differentiation activator isolated from Lindbladia tubulina by our group. Hes1 dimerization inhibitory activity of…”
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Isolation and evaluation of cardenolides from Lansium domesticum as Notch inhibitors
Published in Journal of natural medicines (01-09-2020)“…Since Notch signaling plays important roles in cell proliferation and differentiation, aberrant activation of this signaling contributes to cancer progression…”
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