Search Results - "ISHENGOMA, DEUS S"

Applying next-generation sequencing to track falciparum malaria in sub-Saharan Africa by Tessema, Sofonias K, Raman, Jaishree, Duffy, Craig W, Ishengoma, Deus S, Amambua-Ngwa, Alfred, Greenhouse, Bryan

“…Next-generation sequencing (NGS) technologies are increasingly being used to address a diverse range of biological and epidemiological questions. The current…”
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Performance of antigen detection for HRP2-based malaria rapid diagnostic tests in community surveys: Tanzania, July-November 2017 by Rogier, Eric, Bakari, Catherine, Mandara, Celine I, Chiduo, Mercy G, Plucinski, Mateusz, Nace, Douglas, Battle, Nastassia, Chacky, Franky, Rumisha, Susan F, Molteni, Fabrizio, Mandike, Renata, Mkude, Sigsbert, Njau, Ritha, Mohamed, Ally, Udhayakumar, Venkatachalam, Ishengoma, Deus S

“…Malaria rapid diagnostic tests (RDTs) based on the detection of the Plasmodium falciparum histidine-rich protein 2 (HRP2) antigen are widely used for detection…”
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Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges by Ishengoma, Deus S, Saidi, Queen, Sibley, Carol H, Roper, Cally, Alifrangis, Michael

“…Parasite resistance against anti-malarial drugs is a major threat to the ongoing malaria control and elimination strategies. This is especially true since…”
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Plasmodium malariae structure and genetic diversity in sub-Saharan Africa determined from microsatellite variants and linked SNPs in orthologues of antimalarial resistance genes by Oriero, Eniyou C., Demba, Martha A., Diop, Mouhamadou F., Ishengoma, Deus S., Amenga-Etego, Lucas N., Ghansah, Anita, Apinjoh, Tobias, Issiaka, Soulama, Djimde, Abdoulaye, D’Alessandro, Umberto, Meremikwu, Martin, Amambua-Ngwa, Alfred

“…Plasmodium malariae , a neglected human malaria parasite, contributes up to 10% of malaria infections in sub-Saharan Africa (sSA). Though P. malariae infection…”
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Efficacy and safety of artemisinin-based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania by Kakolwa, Mwaka A, Mahende, Muhidin K, Ishengoma, Deus S, Mandara, Celine I, Ngasala, Billy, Kamugisha, Erasmus, Kataraihya, Johannes B, Mandike, Renata, Mkude, Sigsbert, Chacky, Frank, Njau, Ritha, Premji, Zul, Lemnge, Martha M, Warsame, Marian, Menard, Didier, Kabanywanyi, Abdunoor M

“…Artemisinin-based combination therapy (ACT) is the first-line anti-malarial treatment of uncomplicated malaria in most malaria endemic countries, including…”
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Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients enrolled at 100 health facilities throughout Tanzania: February to July 2021 by Rogier, Eric, Battle, Nastassia, Bakari, Catherine, Seth, Misago D., Nace, Douglas, Herman, Camelia, Barakoti, Achut, Madebe, Rashid A., Mandara, Celine I., Lyimo, Beatus M., Giesbrecht, David J., Popkin-Hall, Zachary R., Francis, Filbert, Mbwambo, Daniel, Garimo, Issa, Aaron, Sijenunu, Lusasi, Abdallah, Molteni, Fabrizio, Njau, Ritha, Cunningham, Jane A., Lazaro, Samwel, Mohamed, Ally, Juliano, Jonathan J., Bailey, Jeffrey A., Udhayakumar, Venkatachalam, Ishengoma, Deus S.

“…Plasmodium falciparum with the histidine rich protein 2 gene ( pfhrp2 ) deleted from its genome can escape diagnosis by HRP2-based rapid diagnostic tests…”
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A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa by Ndwiga, Leonard, Kimenyi, Kelvin M., Wamae, Kevin, Osoti, Victor, Akinyi, Mercy, Omedo, Irene, Ishengoma, Deus S., Duah-Quashie, Nancy, Andagalu, Ben, Ghansah, Anita, Amambua-Ngwa, Alfred, Tukwasibwe, Stephen, Tessema, Sofonias K., Karema, Corine, Djimde, Abdoulaye A., Dondorp, Arjen M., Raman, Jaishree, Snow, Robert W., Bejon, Philip, Ochola-Oyier, Lynette Isabella

“…Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification of the resistance conferring molecular marker, Plasmodium falciparum…”
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Rare diseases in Tanzania: a National Call for Action to address policy and urgent needs of individuals with rare diseases by Kaywanga, Frida, Alimohamed, Mohamed Zahir, David, Aneth Bella, Maeda, Daniel, Mbarak, Sharifa, Mavura, Togolani, Nkya, Siana, Ishengoma, Deus S

“…A rare disease is generally defined as a condition which affects about 1 among 2000 people and currently, there are approximately 5000–8000 rare diseases (RDs)…”
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Genetic polymorphism and evidence of signatures of selection in the Plasmodium falciparum circumsporozoite protein gene in Tanzanian regions with different malaria endemicity by Lyimo, Beatus M, Bakari, Catherine, Popkin-Hall, Zachary R, Giesbrecht, David J, Seth, Misago D, Pereus, Dativa, Shabani, Zulfa I, Moshi, Ramadhan, Boniface, Ruth, Mandara, Celine I, Madebe, Rashid, Juliano, Jonathan J, Bailey, Jeffrey A, Ishengoma, Deus S

“…In 2021 and 2023, the World Health Organization approved RTS,S/AS01 and R21/Matrix M malaria vaccines, respectively, for routine immunization of children in…”
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Evaluation of a single screen and treat strategy to detect asymptomatic malaria among pregnant women from selected health facilities in Lindi region, Tanzania by Kitojo, Chonge, Chacky, Frank, Kigadye, Emmanuel S, Mugasa, Joseph P, Lusasi, Abdallah, Mohamed, Ally, Walker, Patrick, Reaves, Erik J, Gutman, Julie R, Ishengoma, Deus S

“…In areas of high transmission, malaria in pregnancy (MiP) primarily causes asymptomatic infections; these infections nonetheless increase the risk of adverse…”
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Microsatellites reveal high polymorphism and high potential for use in anti-malarial efficacy studies in areas with different transmission intensities in mainland Tanzania by Ishengoma, Deus S, Mandara, Celine I, Madebe, Rashid A, Warsame, Marian, Ngasala, Billy, Kabanywanyi, Abdunoor M, Mahende, Muhidin K, Kamugisha, Erasmus, Kavishe, Reginald A, Muro, Florida, Mandike, Renata, Mkude, Sigsbert, Chacky, Frank, Njau, Ritha, Martin, Troy, Mohamed, Ally, Bailey, Jeffrey A, Fola, Abebe A

“…Tanzania is currently implementing therapeutic efficacy studies (TES) in areas of varying malaria transmission intensities as per the World Health Organization…”
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Acceptability of single screening and treatment policy for the control of malaria in pregnancy: perceptions of providers and pregnant women from selected health facilities in Lindi region, Tanzania by Kitojo, Chonge, Chacky, Frank, Kigadye, Emmanuel S, Mugasa, Joseph P, Lusasi, Abdallah, Mohamed, Ally, Reaves, Erik J, Gutman, Julie R, Ishengoma, Deus S

“…Background Tanzania started implementing single screening and treatment (SST) for all pregnant women attending their first antenatal care (ANC) visits in 2014,…”
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High prevalence and risk of malaria among asymptomatic individuals from villages with high prevalence of artemisinin partial resistance in Kyerwa district of Kagera region, north-western Tanzania by Mandai, Salehe S, Francis, Filbert, Challe, Daniel P, Seth, Misago D, Madebe, Rashid A, Petro, Daniel A, Budodo, Rule, Kisambale, Angelina J, Chacha, Gervas A, Moshi, Ramadhan, Mbwambo, Ruth B, Pereus, Dativa, Bakari, Catherine, Aaron, Sijenunu, Mbwambo, Daniel, Lusasi, Abdallah, Kajange, Stella, Lazaro, Samuel, Kapologwe, Ntuli, Mandara, Celine I, Ishengoma, Deus S

“…Although Tanzania adopted and has been implementing effective interventions to control and eventually eliminate malaria, the disease is still a leading public…”
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Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in mainland Tanzania, 2019 by Ngasala, Billy E, Chiduo, Mercy G, Mmbando, Bruno P, Francis, Filbert T, Bushukatale, Samwel, Makene, Twilumba, Mandara, Celine I, Ishengoma, Deus S, Kamugisha, Erasmus, Ahmed, Maimuna, Mahende, Muhidin K, Kavishe, Reginald A, Muro, Florida, Molteni, Fabrizio, Reaves, Erik, Kitojo, Chonge, Greer, George, Nyinondi, Ssanyu, Kabula, Bilal, Lalji, Shabbir, Chacky, Frank, Njau, Ritha J, Warsame, Marian, Mohamed, Ally

“…Artemisinin-based combination therapy (ACT) has been a major contributor to the substantial reductions in global malaria morbidity and mortality over the last…”
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Community-based surveys for Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in selected regions of mainland Tanzania by Bakari, Catherine, Jones, Sophie, Subramaniam, Gireesh, Mandara, Celine I, Chiduo, Mercy G, Rumisha, Susan, Chacky, Frank, Molteni, Fabrizio, Mandike, Renata, Mkude, Sigsbert, Njau, Ritha, Herman, Camelia, Nace, Douglas P, Mohamed, Ally, Udhayakumar, Venkatachalam, Kibet, Caleb K, Nyanjom, Steven G, Rogier, Eric, Ishengoma, Deus S

“…Histidine-rich protein 2 (HRP2)-based malaria rapid diagnostic tests (RDTs) are effective and widely used for the detection of wild-type Plasmodium falciparum…”
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Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in mainland Tanzania, 2018 by Ngasala, Billy, Chiduo, Mercy G, Bushukatale, Samwel, Mmbando, Bruno P, Makene, Twilumba, Kamugisha, Erasmus, Ahmed, Maimuna, Mandara, Celine I, Francis, Filbert, Mahende, Muhidin K, Kavishe, Reginald A, Muro, Florida, Ishengoma, Deus S, Mandike, Renata, Molteni, Fabrizio, Chacky, Frank, Kitojo, Chonge, Greer, George, Bishanga, Dunstan, Chadewa, Jasmine, Njau, Ritha, Warsame, Marian, Kabula, Bilali, Nyinondi, Ssanyu S, Reaves, Erik, Mohamed, Ally

“…The use of artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated falciparum malaria…”
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IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria by Turner, Louise, Lavstsen, Thomas, Mmbando, Bruno P, Wang, Christian W, Magistrado, Pamela A, Vestergaard, Lasse S, Ishengoma, Deus S, Minja, Daniel T R, Lusingu, John P, Theander, Thor G

“…Severe malaria syndromes are precipitated by Plasmodium falciparum parasites binding to endothelial receptors on the vascular lining. This binding is mediated…”
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Estimating malaria burden among pregnant women using data from antenatal care centres in Tanzania: a population-based study by Kitojo, Chonge, Gutman, Julie R, Chacky, Frank, Kigadye, Emmanuel, Mkude, Sigsbert, Mandike, Renata, Mohamed, Ally, Reaves, Erik J, Walker, Patrick, Ishengoma, Deus S

“…More timely estimates of malaria prevalence are needed to inform optimal control strategies and measure progress. Since 2014, Tanzania has implemented…”
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Prevalence of non-falciparum malaria infections among asymptomatic individuals in four regions of Mainland Tanzania by Popkin-Hall, Zachary R, Seth, Misago D, Madebe, Rashid A, Budodo, Rule, Bakari, Catherine, Francis, Filbert, Pereus, Dativa, Giesbrecht, David J, Mandara, Celine I, Mbwambo, Daniel, Aaron, Sijenunu, Lusasi, Abdallah, Lazaro, Samwel, Bailey, Jeffrey A, Juliano, Jonathan J, Gutman, Julie R, Ishengoma, Deus S

“…Recent studies point to the need to incorporate the detection of non-falciparum species into malaria surveillance activities in sub-Saharan Africa, where 95%…”
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Community knowledge, attitude, practices and beliefs associated with persistence of malaria transmission in North-western and Southern regions of Tanzania by Liheluka, Edwin A, Massawe, Isolide S, Chiduo, Mercy G, Mandara, Celine I, Chacky, Frank, Ndekuka, Leah, Temba, Filbert F, Mmbando, Bruno P, Seth, Misago D, Challe, Daniel P, Makunde, Williams H, Mhina, Athanas D, Baraka, Vito, Segeja, Method D, Derua, Yahya A, Batengana, Bernard M, Hayuma, Paul M, Madebe, Rashid A, Malimi, Masunga C, Mandike, Renata, Mkude, Sigsbert, Molteni, Fabrizio, Njau, Ritha, Mohamed, Ally, Rumisha, Susan F, Ishengoma, Deus S

“…Despite significant decline in the past two decades, malaria is still a major public health concern in Tanzania; with over 93% of the population still at risk…”
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