Search Results - "IRVING, W. L."

Prevalence and risk factors for hepatitis C virus infection in Kech District, Balochistan, Pakistan: most infections remain unexplained. A cross-sectional study by AHMED, F., IRVING, W. L., ANWAR, M., MYLES, P., NEAL, K. R.

“…We studied a cross-sectional sample of the population of Kech, a small rural town in Pakistan to determine the prevalence and risk factors for hepatitis C…”
Get full text

Influenza virus infection in the second and third trimesters of pregnancy: a clinical and seroepidemiological study by Irving, W. L., James, D. K., Stephenson, T., Laing, P., Jameson, C., Oxford, J. S., Chakraverty, P., Brown, D. W. G., Boon, A. C. M, Zambon, M. C.

“…Objective To determine whether maternal influenza virus infection in the second and third trimesters of pregnancy results in transplacental transmission of…”
Get full text

Association between MHC Class II Alleles and Clearance of Circulating Hepatitis C Virus by Minton, E. J., Smillie, D., Neal, K. R., Irving, W. L., Underwood, J. C. E., James, V.

“…The frequencies of HLA class I antigens and class II haplotypes were compared in subjects with previous (polymerase chain reaction [PCR]-negative) or with…”
Get full text

Immunocompromised children and young people are at no increased risk of severe COVID-19 by Chappell, H., Patel, R., Driessens, C., Tarr, A.W., Irving, W.L., Tighe, P.J., Jackson, H.J., Harvey-Cowlishaw, T., Mills, L., Shaunak, M., Gbesemete, D., Leahy, A., Lucas, J.S., Faust, S.N., de Graaf, H.

“…•UK immunocompromised paediatric patients were at no increased risk of severe COVID-19.•Only 4/38 PCR detected infections were admitted to hospital. None had…”
Get full text

Severe fibrosis in hepatitis C virus‐infected patients is associated with increased activity of the mannan‐binding lectin (MBL)/MBL‐associated serine protease 1 (MASP‐1) complex by Brown, K. S., Keogh, M. J., Tagiuri, N., Grainge, M. J., Presanis, J. S., Ryder, S. D., Irving, W. L., Ball, J. K., Sim, R. B., Hickling, T. P.

“…Summary Mannan‐binding lectin (MBL) binds microorganisms via interactions with glycans on the target surface. Bound MBL subsequently activates MBL‐associated…”
Get full text

Host genetic factors associated with hepatocellular carcinoma in patients with hepatitis C virus infection: A systematic review by Walker, A. J., Peacock, C. J., Pedergnana, V., Irving, W. L.

“…Summary Hepatitis C virus (HCV)‐infected patients are at risk of developing hepatocellular carcinoma (HCC). Individuals at heightened risk could be targeted by…”
Get full text

Clinical pathways for patients with newly diagnosed hepatitis C - What actually happens by Irving, W. L., Smith, S., Cater, R., Pugh, S., Neal, K. R., Coupland, C. A. C., Ryder, S. D., Thomson, B. J., Pringle, M., Bicknell, M., Hippisley-Cox, J.

“…Management of hepatitis C virus (HCV)‐infected individuals requires referral to specialist care. To determine whether patients newly diagnosed as anti‐HCV…”
Get full text

Short-term changes observed in multiparametric liver MRI following therapy with direct-acting antivirals in chronic hepatitis C virus patients by Bradley, C., Scott, R. A., Cox, E., Palaniyappan, N., Thomson, B. J., Ryder, S. D., Irving, W. L., Aithal, G. P., Guha, I. N., Francis, S.

“…Methods We applied multiparametric MRI to assess changes in liver composition, perfusion and blood flow in 17 patients before direct-acting antiviral (DAA)…”
Get full text

Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank by McLauchlan, J, Innes, H, Dillon, J F, Foster, G, Holtham, E, McDonald, S, Wilkes, B, Hutchinson, S J, Irving, W L

Get full text

Current knowledge and future perspectives on acute hepatitis C infection by Hullegie, S.J., Arends, J.E., Rijnders, B.J.A., Irving, W.L., Salmon, D., Prins, M., Wensing, A.M., Klenerman, P., Leblebicioglu, H., Boesecke, C., Rockstroh, J.K., Hoepelman, A.I.M.

“…Acute hepatitis C virus (HCV) infections are frequently seen worldwide in certain risk groups, with an annual incidence rate varying between 0.08% and 66%…”
Get full text

TT Virus Infection in Patients with Hepatitis C: Frequency, Persistence, and Sequence Heterogeneity by Irving, William L., Ball, Jonathan K., Berridge, Selina, Curran, Rebecca, Grabowska, Anna M., Jameson, Claire L., Neal, Keith R., Ryder, Steven D., Thomson, Brian J.

“…TT virus (TTV) was recently identified in the serum of a patient with hepatitis. The role of TTV in liver disease has not been established. Three polymerase…”
Get full text

The cost of treatment failure: resource use and costs incurred by hepatitis C virus genotype 1-infected patients who do or do not achieve sustained virological response to therapy by Backx, M., Lewszuk, A., White, J. R., Cole, J., Sreedharan, A., van Sanden, S., Diels, J., Lawson, A., Neal, K. R., Wiselka, M. J., Ito, T., Irving, W. L.

“…Summary Chronic hepatitis C virus (HCV) infection places a considerable economic burden on health services. Cost‐effectiveness analyses of antiviral treatment…”
Get full text

Immunisation with Phage Displaying Peptides Representing Single Epitopes of the Glycoprotein G Can Give Rise to Partial Protective Immunity to HSV-2 by Grabowska, A.M., Jennings, R., Laing, P., Darsley, M., Jameson, C.L., Swift, L., Irving, W.L.

“…Filamentous phage displaying peptides representing single epitopes of the glycoprotein G of HSV-2 (gG2) were used as immunogens via the subcutaneous route in…”
Get full text

Evolutionary trends of the first hypervariable region of the hepatitis C virus E2 protein in individuals with differing liver disease severity by Curran, Rebecca, Jameson, Claire L, Craggs, Joanna K, Grabowska, Anna M, Thomson, Brian J, Robins, Adrian, Irving, William L, Ball, Jonathan K

“…Division of Microbiology and Infectious Diseases, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK 1 Author for correspondence:…”
Get full text

Acute hepatitis C virus infection: a neglected disease? by Irving, W L

“…[...]there remains a possibility that the sex difference in clearance is secondary to differences in age at, and route of, acquisition of infection, although…”
Get full text

Detection of immunoglobulin M antibodies to glycoprotein G-2 by western blot (immunoblot) for diagnosis of initial herpes simplex virus type 2 genital infections by HO, D. W. T, FIELD, P. R, IRVING, W. L, PACKHAM, D. R, CUNNINGHAM, A. L

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Autoantibodies in chronic hepatitis C virus infection and their association with disease profile by Williams, M. J., Lawson, A., Neal, K. R., Ryder, S. D., Irving, W. L.

“…Autoantibodies are commonly detected in chronic hepatitis C (HCV) but their significance remains uncertain. We assessed the prevalence of anti‐nuclear (ANA)…”
Get full text

Reasons for nonuse of antiviral treatment in patients with chronic hepatitis C infection and thrombocytopaenia: a retrospective chart review from five European countries by Rizzetto, M., Grotzinger, K., Theodore, D., Demuth, D., Irving, W. L., Manns, M., Roughley, A., Forssen, U. M.

“…Summary Antiviral therapy has been shown to reduce the risk of disease progression, liver damage and death in patients with chronic hepatitis C virus (HCV)…”
Get full text

Antiviral treatment discontinuation among hepatitis C-infected individuals with thrombocytopenia by Irving, W. L., Grotzinger, K., Theodore, D., Demuth, D., Rizzetto, M., Roughley, A., Forssen, U.

Get full text

Dendritic cells cultured from mononuclear cells and CD34 cells in myeloma do not harbour human herpesvirus 8 by CULL, G. M, TIMMS, J. M, HAYNES, A. P, RUSSELL, N. H, IRVING, W. L, BALL, J. K, THOMSON, B. J

“…Dendritic cells (DC) are antigen‐presenting cells with the potential to be a powerful adjuvant in the immunotherapy of haematological malignancy, including…”
Get full text