Search Results - "IONESCU, Lucian"

Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study by Smolen, Josef S, Prof, Burmester, Gerd-Rüdiger, Prof, Combe, Bernard, Prof, Curtis, Jeffrey R, Prof, Hall, Stephen, MD, Haraoui, Boulos, MD, van Vollenhoven, Ronald, Prof, Cioffi, Christopher, PhD, Ecoffet, Cécile, PharmD, Gervitz, Leon, PhD, Ionescu, Lucian, MD, Peterson, Luke, MS, Fleischmann, Roy, Prof

“…Summary Background To date, head-to-head trials comparing the efficacy and safety of biological disease-modifying antirheumatic drugs within the same class,…”
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Classification of Holomorphic Functions as Pólya Vector Fields via Differential Geometry by Ionescu, Lucian-Miti, Pripoae, Cristina-Liliana, Pripoae, Gabriel-Teodor

“…We review Pólya vector fields associated to holomorphic functions as an important pedagogical tool for making the complex integral understandable to the…”
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Petrochronological Evidence for a Three-Stage Magmatic Evolution of the Youngest Nepheline Syenites from the Ditrău Alkaline Massif, Romania by Urs Klötzli, Jolanta Burda, Qiu-Li Li, Yu Liu, Gyula Jakab, Lucian Ionescu, Paul Tibuleac

“…The Ditrău Alkaline Massif (DAM) is an igneous massif in the Eastern Carpathian Mountains of Romania. Numerous geochronological and geochemical studies have…”
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Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: implications for quartal Ca2+release by Ionescu, Lucian, Cheung, King‐Ho, Vais, Horia, Mak, Don‐On Daniel, White, Carl, Foskett, J. Kevin

“…Modulation of cytoplasmic free Ca 2 + concentration ([Ca 2 + ] i ) by receptor-mediated generation of inositol 1,4,5-trisphosphate (InsP 3 ) and activation of…”
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Elisa preliminary studies of immobilization and specific detection of bacterial strains by Mihalache, Madalina, Banciu, Alina, Ionescu, Lucian, Nita-Lazar, Mihai

“…The paper aims to emphasize the specific detection of bacterial strains using enzyme-linked immunosorbent assay. The assay is based on the specific binding of…”
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Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation by Glatt, Sophie, Baeten, Dominique, Baker, Terry, Griffiths, Meryn, Ionescu, Lucian, Lawson, Alastair D G, Maroof, Ash, Oliver, Ruth, Popa, Serghei, Strimenopoulou, Foteini, Vajjah, Pavan, Watling, Mark I L, Yeremenko, Nataliya, Miossec, Pierre, Shaw, Stevan

“…Interleukin (IL)-17A has emerged as pivotal in driving tissue pathology in immune-mediated inflammatory diseases. The role of IL-17F, sharing 50% sequence…”
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Efficacy and Safety of Bimekizumab in Moderate to Severe Hidradenitis Suppurativa: A Phase 2, Double-blind, Placebo-Controlled Randomized Clinical Trial by Glatt, Sophie, Jemec, Gregor B E, Forman, Seth, Sayed, Christopher, Schmieder, George, Weisman, Jamie, Rolleri, Robert, Seegobin, Seth, Baeten, Dominique, Ionescu, Lucian, Zouboulis, Christos C, Shaw, Stevan

“…Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a high burden for patients and limited existing therapeutic options. To evaluate the…”
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Mode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels by Ionescu, Lucian, White, Carl, Cheung, King-Ho, Shuai, Jianwei, Parker, Ian, Pearson, John E, Foskett, J Kevin, Mak, Don-On Daniel

“…The inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) plays a critical role in generation of complex Ca(2+) signals in many cell types. In patch clamp…”
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NONASSOCIATIVE ALGEBRAS: A FRAMEWORK FOR DIFFERENTIAL GEOMETRY by Ionescu, Lucian M.

“…A nonassociative algebra endowed with a Lie bracket, called a torsion algebra , is viewed as an algebraic analog of a manifold with an affine connection. Its…”
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Efficacy and safety of bimekizumab as add-on therapy for rheumatoid arthritis in patients with inadequate response to certolizumab pegol: a proof-of-concept study by Glatt, Sophie, Taylor, Peter C, McInnes, Iain B, Schett, Georg, Landewé, Robert, Baeten, Dominique, Ionescu, Lucian, Strimenopoulou, Foteini, Watling, Mark I L, Shaw, Stevan

“…Evaluate the efficacy and safety of dual neutralisation of interleukin (IL)-17A and IL-17F with bimekizumab, a monoclonal IgG1 antibody, in addition to…”
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EVALUATING THE ECOTOXICITY OF DIFFERENT PHARMACEUTICALS USING ALIIVIBRIO FISCHERI BIOASSAYS by Ionescu, Lucian, Gheorghe, Stefania, Mitru, Daniel, Stoica, Catalina, Banciu, Alina Roxana, Mihalache, Madalina, Nita-Lazar, Mihai

“…An endless list of companies has produced a large amount of pharmaceutical compounds in a year-on-year growth trend. Due to the excessive consumption of these…”
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On ideals and homology in additive categories by Ionescu, Lucian M.

“…Ideals are used to define homological functors in additive categories. In abelian categories the ideals corresponding to the usual universal objects are…”
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Increasing stability of crew and aircraft schedules by Dück, Viktor, Ionescu, Lucian, Kliewer, Natalia, Suhl, Leena

“…► We introduce an integrated stochastic model for aircraft and crew scheduling. ► The model is solved by a heuristic solution approach based on column…”
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Data Analysis of Delays in Airline Networks by Ionescu, Lucian, Gwiggner, Claus, Kliewer, Natalia

“…Cost-optimized airline resource schedules often imply a lack of delay tolerance in case of unforeseen disruptions, e.g. late check-ins, technical defects or…”
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INFLAMMATORY BOWEL DISEASE AND SEROLOGIC MARKERS OF INFLAMMATION by IONESCU, Andra Consuela, GAMAN, Laura Elena, VASILESCU, Alina, ATANASIU, Valeriu, IONESCU, Lucian, DICULESCU, Mihai Mircea

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INFLAMMATORY BOWEL DISEASE AND SEROLOGIC MARKERS OF INFLAMMATION by Ionescu, Andra Consuela, Gaman, Laura Elena, Vasilescu, Alina, Atanasiu, Valeriu, Ionescu, Lucian, Diculescu, Mihai Mircea

“…INFLAMMATORY BOWEL DISEASES, CROHN DISEASE AND ULCERATIVE COLITIS, CAUSE CHRONIC INFLAMMATION OF THE DIGESTIVE TRACT, TRIGGERED BY A COMPLEX INTERACTION OF…”
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Timing and Magnitude of Initial Change in Disease Activity Score 28 Predicts the Likelihood of Achieving Low Disease Activity at 1 Year in Rheumatoid Arthritis Patients Treated with Certolizumab Pegol: A Post-hoc Analysis of the RAPID 1 Trial by VAN DER HEIJDE, Desiree, KEYSTONE, Edward C, LUIJTENS, Kristel, FURST, Daniel E, CURTIS, Jeffrey R, LANDEWE, Robert B, SCHIFF, Michael H, KHANNA, Dinesh, KVIEN, Tore K, IONESCU, Lucian, GERVITZ, Leon M, DAVIES, Owen R

“…To determine the relationship between timing and magnitude of Disease Activity Score [DAS28(ESR)] nonresponse (DAS28 improvement thresholds not reached) during…”
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NECESSITY OF A NEW TYPE OF SYMBIOSIS BETWEEN THE NOMINAL AND THE REAL ECONOMY by Lucian C. IONESCU

“…This paper deals with the rift between the nominal economy and the evolution of the real economy, which represented the main structural cause for the…”
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Certolizumab Pegol Efficacy Across Methotrexate Regimens: A Pre‐Specified Analysis of Two Phase III Trials by Combe, Bernard, Furst, Daniel E., Keystone, Edward C., van der Heijde, Désirée, Luijtens, Kristel, Ionescu, Lucian, Goel, Niti, Emery, Paul

“…Objective Anti–tumor necrosis factor (anti‐TNF) agents are frequently used in combination with methotrexate (MTX) to treat rheumatoid arthritis (RA). We…”
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On Prime Numbers and The Riemann Zeros by Ionescu, Lucian M

“…Journal of Advances in Applied Mathematics, Vol. 2, No. 4, October 2017 The current research regarding the Riemann zeros suggests the existence of a…”
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