Search Results - "INOUE, TOMIO"
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1
Neuroendocrine tumor theranostics
Published in Cancer science (01-06-2022)“…Theranostics is a term coined by combining the words “therapeutics” and “diagnostics,” referring to single chemical entities developed to deliver therapy and…”
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2
Generation of orthotopically functional salivary gland from embryonic stem cells
Published in Nature communications (11-10-2018)“…Organoids generated from pluripotent stem cells are used in the development of organ replacement regenerative therapy by recapitulating the process of…”
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3
Myricetin prevents high molecular weight Aβ1-42 oligomer-induced neurotoxicity through antioxidant effects in cell membranes and mitochondria
Published in Free radical biology & medicine (01-08-2021)“…Excessive accumulation of amyloid β-protein (Aβ) is one of the primary mechanisms that leads to neuronal death with phosphorylated tau in the pathogenesis of…”
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4
Effects of Canagliflozin on Hepatic Steatosis, Visceral Fat and Skeletal Muscle among Patients with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease
Published in Internal Medicine (01-11-2021)“…Objective We assessed the effect of canagliflozin, an sodium-glucose co-transporter type-2 inhibitor, on hepatic steatosis using three imaging modalities:…”
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5
Involvement of ghrelin in the regulation of swallowing motor activity in an arterially perfused rat preparation
Published in Brain research bulletin (01-01-2023)“…Ghrelin, a peripheral peptide produced in the stomach, is involved in the neural networks that control food intake. Alterations in motor components, such as…”
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6
Optogenetic activation of serotonergic neurons changes masticatory movement in freely moving mice
Published in Scientific reports (12-11-2024)“…The serotonergic system modulates the neural circuits involved in jaw movement; however, the role of serotonin (5-HT) neurons in masticatory movement remains…”
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7
Efferent and afferent connections of supratrigeminal neurons conveying orofacial muscle proprioception in rats
Published in Brain Structure and Function (01-01-2022)“…The supratrigeminal nucleus (Su5) is a key structure for controlling jaw movements; it receives proprioceptive sensation from jaw-closing muscle spindles…”
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8
Intrinsic properties and synaptic connectivity of Phox2b-expressing neurons in rat rostral parvocellular reticular formation
Published in Neuroscience research (01-05-2022)“…•Most Phox2b+ rPCRt neurons were glutamatergic, but not GABAergic/glycinergic.•The firing characteristics differ between Phox2b+ neurons in the rPCRt and…”
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9
Use of PET and PET/CT for Radiation Therapy Planning: IAEA expert report 2006–2007
Published in Radiotherapy and oncology (01-04-2009)“…Abstract Positron Emission Tomography (PET) is a significant advance in cancer imaging with great potential for optimizing radiation therapy (RT) treatment…”
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10
Modulators of radiation-induced cardiopulmonary toxicities for non-small cell lung cancer: Integrated cytokines, single nucleotide variants, and HBP systems imaging
Published in Frontiers in oncology (15-12-2022)“…Radiation therapy (RT)-induced cardiopulmonary toxicities remain dose-limiting toxicities for patients receiving radiation dosages to the thorax, especially…”
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11
Postnatal Maturation of Glutamatergic Inputs onto Rat Jaw-closing and Jaw-opening Motoneurons
Published in Neuroscience (01-01-2022)“…•A diversity of developmental changes in the trigeminal motoneurons was observed.•Jaw-closing motoneurons showed decreased decay time of non-NMDA mEPSCs with…”
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12
Developmental changes in GABAergic and glycinergic synaptic transmission to rat motoneurons innervating jaw-closing and jaw-opening muscles
Published in Brain research (15-02-2022)“…[Display omitted] •Jaw-closing and opening motoneurons showed GABAergic and glycinergic mIPSCs.•GABAergic and Glycinergic mIPSCs mature differently between…”
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13
Confocal calcium imaging analysis of respiratory-related burst activity in the parafacial region
Published in Brain research bulletin (01-05-2018)“…•Phox2b is a good genetic marker of parafacial neurons in the rostral medulla.•It is not clear what percentage of Phox2b-expressing cells show rhythmic burst…”
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14
Enhancement of swallowing motor activity by the ACE inhibitor imidapril in an arterially perfused rat preparation
Published in European journal of pharmacology (15-10-2019)“…Pharmacological agents that elevate dopamine and substance P concentrations have been suggested to prevent aspiration pneumonia and improve impaired swallowing…”
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15
5‐HT2A receptor activation enhances NMDA receptor‐mediated glutamate responses through Src kinase in the dendrites of rat jaw‐closing motoneurons
Published in The Journal of physiology (01-05-2019)“…Key points 5‐HT increases the excitability of brainstem and spinal motoneurons, including the jaw‐closing motoneurons, by depolarizing the membrane potential…”
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16
Diagnostic performance and safety of NMK36 (trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid)-PET/CT in primary prostate cancer: multicenter Phase IIb clinical trial
Published in Japanese journal of clinical oncology (01-02-2016)“…We performed a multicenter Phase IIb clinical trial of NMK36, a novel amino acid analog for positron emission tomography containing…”
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17
In vitro monitoring of HTR2A-positive neurons derived from human-induced pluripotent stem cells
Published in Scientific reports (29-07-2021)“…The serotonin 5-HT 2A receptor (5-HT 2A R) has been receiving increasing attention because its genetic variants have been associated with a variety of…”
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18
Goji Berry Juice Prevents Tumor Necrosis Factor Alpha-Induced Xerostomia in Human Salivary Gland Cells
Published in Biological & pharmaceutical bulletin (01-01-2024)“…Sjögren’s syndrome (SS) is an autoimmune disorder characterized by oral dryness that is primarily attributed to tumor necrosis factor alpha (TNF-α)-mediated…”
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19
A preliminary report of breast cancer screening by positron emission mammography
Published in Annals of nuclear medicine (01-02-2016)“…Objective Fluorine-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET) and PET/computed tomography (PET/CT) have had a considerable impact on the…”
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20
Responses evoked by electrical stimulation of the brainstem reticular formation in the jaw-opening and hypoglossal motor nerves of an arterially perfused rat preparation
Published in Neuroscience letters (01-11-2020)“…•Stimulation of the extensive brainstem evokes motor activity in orofacial nerve.•Mean latency is shorter in the mylohyoid nerve than the hypoglossal…”
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