Search Results - "INOKO, HIDETOSHI"

The HLA genomic loci map: expression, interaction, diversity and disease by Shiina, Takashi, Hosomichi, Kazuyoshi, Inoko, Hidetoshi, Kulski, Jerzy K

“…The human leukocyte antigen (HLA) super-locus is a genomic region in the chromosomal position 6p21 that encodes the six classical transplantation HLA genes and…”
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Comparative genomics of the human, macaque and mouse major histocompatibility complex by Shiina, Takashi, Blancher, Antoine, Inoko, Hidetoshi, Kulski, Jerzy K.

“…Summary The MHC is a highly polymorphic genomic region that encodes the transplantation and immune regulatory molecules. It receives special attention for…”
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Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B51 and ERAP1 by Kirino, Yohei, Bertsias, George, Ishigatsubo, Yoshiaki, Mizuki, Nobuhisa, Tugal-Tutkun, Ilknur, Seyahi, Emire, Ozyazgan, Yilmaz, Sacli, F Sevgi, Erer, Burak, Inoko, Hidetoshi, Emrence, Zeliha, Cakar, Atilla, Abaci, Neslihan, Ustek, Duran, Satorius, Colleen, Ueda, Atsuhisa, Takeno, Mitsuhiro, Kim, Yoonhee, Wood, Geryl M, Ombrello, Michael J, Meguro, Akira, Gül, Ahmet, Remmers, Elaine F, Kastner, Daniel L

“…Daniel Kastner and colleagues report genome-wide association analyses for Behçet's disease, a condition characterized by episodic inflammation of the skin and…”
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Genome-wide association studies identify IL23R - IL12RB2 and IL10 as Behçet's disease susceptibility loci by Mizuki, Nobuhisa, Inoko, Hidetoshi, Meguro, Akira, Ota, Masao, Ohno, Shigeaki, Shiota, Tomoko, Kawagoe, Tatsukata, Ito, Norihiko, Kera, Jiro, Okada, Eiichi, Yatsu, Keisuke, Song, Yeong-Wook, Lee, Eun-Bong, Kitaichi, Nobuyoshi, Namba, Kenichi, Horie, Yukihiro, Takeno, Mitsuhiro, Sugita, Sunao, Mochizuki, Manabu, Bahram, Seiamak, Ishigatsubo, Yoshiaki

“…Behçet's disease is a chronic systemic inflammatory disorder characterized by four major manifestations: recurrent ocular symptoms, oral and genital ulcers and…”
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High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism by Kawase, Takakazu, Morishima, Yasuo, Matsuo, Keitaro, Kashiwase, Koichi, Inoko, Hidetoshi, Saji, Hiroh, Kato, Shunichi, Juji, Takeo, Kodera, Yoshihisa, Sasazuki, Takehiko

“…In allogenic hematopoietic stem-cell transplantation, an effect of HLA locus mismatch in allele level on clinical outcome has been clarified. However, the…”
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Gene Map of the HLA Region, Graves' Disease and Hashimoto Thyroiditis, and Hematopoietic Stem Cell Transplantation by Sasazuki, Takehiko, Inoko, Hidetoshi, Morishima, Satoko, Morishima, Yasuo

“…The human leukocyte antigen (HLA) genomic region spanning about 4 Mb is the most gene dense and the polymorphic stretches in the human genome. A total of the…”
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Genome-Wide Association Study in Asians Identifies Novel Loci for High Myopia and Highlights a Nervous System Role in Its Pathogenesis by Meguro, Akira, Yamane, Takahiro, Takeuchi, Masaki, Miyake, Masahiro, Fan, Qiao, Zhao, Wanting, Wang, I-Jong, Mizuki, Yuki, Yamada, Norihiro, Nomura, Naoko, Tsujikawa, Akitaka, Matsuda, Fumihiko, Hosoda, Yoshikatsu, Saw, Seang-Mei, Cheng, Ching-Yu, Tsai, Tzu-Hsun, Yoshida, Masao, Iijima, Yasuhito, Teshigawara, Takeshi, Okada, Eiichi, Ota, Masao, Inoko, Hidetoshi, Mizuki, Nobuhisa

“…To identify novel susceptibility loci for high myopia. Genome-wide association study (GWAS) followed by replication and meta-analysis. A total of 14 096…”
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Matching for the nonconventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD by Carapito, Raphael, Jung, Nicolas, Kwemou, Marius, Untrau, Meiggie, Michel, Sandra, Pichot, Angélique, Giacometti, Gaëlle, Macquin, Cécile, Ilias, Wassila, Morlon, Aurore, Kotova, Irina, Apostolova, Petya, Schmitt-Graeff, Annette, Cesbron, Anne, Gagne, Katia, Oudshoorn, Machteld, van der Holt, Bronno, Labalette, Myriam, Spierings, Eric, Picard, Christophe, Loiseau, Pascale, Tamouza, Ryad, Toubert, Antoine, Parissiadis, Anne, Dubois, Valérie, Lafarge, Xavier, Maumy-Bertrand, Myriam, Bertrand, Frédéric, Vago, Luca, Ciceri, Fabio, Paillard, Catherine, Querol, Sergi, Sierra, Jorge, Fleischhauer, Katharina, Nagler, Arnon, Labopin, Myriam, Inoko, Hidetoshi, von dem Borne, Peter A., Kuball, Jürgen, Ota, Masao, Katsuyama, Yoshihiko, Michallet, Mauricette, Lioure, Bruno, Peffault de Latour, Régis, Blaise, Didier, Cornelissen, Jan J., Yakoub-Agha, Ibrahim, Claas, Frans, Moreau, Philippe, Milpied, Noël, Charron, Dominique, Mohty, Mohamad, Zeiser, Robert, Socié, Gérard, Bahram, Seiamak

“…Graft-versus-host disease (GVHD) is among the most challenging complications in unrelated donor hematopoietic cell transplantation (HCT). The highly…”
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Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behçet disease by Kirino, Yohei, Zhou, Qing, Ishigatsubo, Yoshiaki, Mizuki, Nobuhisa, Tugal-Tutkun, Ilknur, Seyahi, Emire, Özyazgan, Yilmaz, Ugurlu, Serdal, Erer, Burak, Abaci, Neslihan, Ustek, Duran, Meguro, Akira, Ueda, Atsuhisa, Takeno, Mitsuhiro, Inoko, Hidetoshi, Ombrello, Michael J., Satorius, Colleen L., Maskeri, Baishali, Mullikin, James C., Sun, Hong-Wei, Gutierrez-Cruz, Gustavo, Kim, Yoonhee, Wilson, Alexander F., Kastner, Daniel L., Gül, Ahmet, Remmers, Elaine F.

“…Genome-wide association studies (GWAS) are a powerful means of identifying genes with disease-associated common variants, but they are not well-suited to…”
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Identification of HLA-DRB104:10 allele as risk allele for Japanese moyamoya disease and its association with autoimmune thyroid disease: A case-control study by Tashiro, Ryosuke, Niizuma, Kuniyasu, Khor, Seik-Soon, Tokunaga, Katsushi, Fujimura, Miki, Sakata, Hiroyuki, Endo, Hidenori, Inoko, Hidetoshi, Ogasawara, Koetsu, Tominaga, Teiji

“…Moyamoya disease (MMD) is a progressive cerebrovascular disease with unknown etiology. Growing evidence suggest its involvement of autoimmune and genetic…”
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Current understanding of human genetics and genetic analysis of psoriasis by OKA, Akira, MABUCHI, Tomotaka, OZAWA, Akira, INOKO, Hidetoshi

“…During the past 5 years, genome‐wide association studies (GWAS), primarily based on single nucleotide polymorphism markers, have identified many loci as…”
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RAR-related orphan receptor A (RORA): A new susceptibility gene for multiple sclerosis by Eftekharian, Mohammad Mahdi, Noroozi, Rezvan, Sayad, Arezou, Sarrafzadeh, Shaghayegh, Toghi, Mehdi, Azimi, Tahereh, Komaki, Alireza, Mazdeh, Mehrdokht, Inoko, Hidetoshi, Taheri, Mohammad, Mirfakhraie, Reza

“…Abstract Retinoic acid receptor-related orphan receptor alpha (RORA) is proposed to promote Th17 cells differentiation that play a crucial role in many…”
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Which CIDE are you on? Apoptosis and energy metabolism by Yonezawa, Tomo, Kurata, Riho, Kimura, Minoru, Inoko, Hidetoshi

“…Around 1998, cell death-inducing DNA fragmentation factor-alpha (DFFA)-like effector (CIDE) proteins including CIDEA, CIDEB and CIDEC/fat specific protein 27…”
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Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism by Ota, Masao, Fukushima, Hirofumi, Kulski, Jerzy K, Inoko, Hidetoshi

“…Accurate analysis of DNA sequence variation in not only humans and animals but also other organisms has played a significant role in expanding our knowledge…”
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Aggregation of rare/low-frequency variants of the mitochondria respiratory chain-related proteins in rheumatoid arthritis patients by Mitsunaga, Shigeki, Hosomichi, Kazuyoshi, Okudaira, Yuko, Nakaoka, Hirofumi, Suzuki, Yasuo, Kuwana, Masataka, Sato, Shinji, Kaneko, Yuko, Homma, Yasuhiko, Oka, Akira, Shiina, Takashi, Inoko, Hidetoshi, Inoue, Ituro

“…Exome sequencings were conducted using 59 patients having rheumatoid arthritis (RA) and 93 controls. After stepwise filtering, 107 genes showed less than 0.05…”
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Cost-efficient multiplex PCR for routine genotyping of up to nine classical HLA loci in a single analytical run of multiple samples by next generation sequencing by Ozaki, Yuki, Suzuki, Shingo, Kashiwase, Koichi, Shigenari, Atsuko, Okudaira, Yuko, Ito, Sayaka, Masuya, Anri, Azuma, Fumihiro, Yabe, Toshio, Morishima, Satoko, Mitsunaga, Shigeki, Satake, Masahiro, Ota, Masao, Morishima, Yasuo, Kulski, Jerzy K, Saito, Katsuyuki, Inoko, Hidetoshi, Shiina, Takashi

“…HLA genotyping by next generation sequencing (NGS) requires three basic steps, PCR, NGS, and allele assignment. Compared to the conventional methods, such as…”
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HLA Association among Thai Patients with Diffuse and Limited Cutaneous Systemic Sclerosis by Louthrenoo, Worawit, Kasitanon, Nuntana, Wongthanee, Antika, Okudaira, Yuko, Takeuchi, Asuka, Noguchi, Hiroshi, Inoko, Hidetoshi, Takeuchi, Fujio

“…This study aimed to clarify the association of HLA Class I and II with dcSSc and lcSSc in Thais. HLA typing for 11 gene loci (Class I: HLA-A, B and C, and…”
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Reference Grade Characterization of Polymorphisms in Full-Length HLA Class I and II Genes With Short-Read Sequencing on the ION PGM System and Long-Reads Generated by Single Molecule, Real-Time Sequencing on the PacBio Platform by Suzuki, Shingo, Ranade, Swati, Osaki, Ken, Ito, Sayaka, Shigenari, Atsuko, Ohnuki, Yuko, Oka, Akira, Masuya, Anri, Harting, John, Baybayan, Primo, Kitazume, Miwako, Sunaga, Junichi, Morishima, Satoko, Morishima, Yasuo, Inoko, Hidetoshi, Kulski, Jerzy K, Shiina, Takashi

“…Although NGS technologies fuel advances in high-throughput HLA genotyping methods for identification and classification of HLA genes to assist with precision…”
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Genetic variants on chromosome 1q41 influence ocular axial length and high myopia by Fan, Qiao, Barathi, Veluchamy A, Cheng, Ching-Yu, Zhou, Xin, Meguro, Akira, Nakata, Isao, Khor, Chiea-Chuen, Goh, Liang-Kee, Li, Yi-Ju, Lim, Wan'e, Ho, Candice E H, Hawthorne, Felicia, Zheng, Yingfeng, Chua, Daniel, Inoko, Hidetoshi, Yamashiro, Kenji, Ohno-Matsui, Kyoko, Matsuo, Keitaro, Matsuda, Fumihiko, Vithana, Eranga, Seielstad, Mark, Mizuki, Nobuhisa, Beuerman, Roger W, Tai, E-Shyong, Yoshimura, Nagahisa, Aung, Tin, Young, Terri L, Wong, Tien-Yin, Teo, Yik-Ying, Saw, Seang-Mei

“…As one of the leading causes of visual impairment and blindness, myopia poses a significant public health burden in Asia. The primary determinant of myopia is…”
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Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6 by Ohtsuka, Masato, Inoko, Hidetoshi, Kulski, Jerzy K, Yoshimura, Shinichi

“…The mouse has more than 30 Major histocompatibility complex (Mhc) class Ib genes, most of which exist in the H2 region of chromosome 17 in distinct gene…”
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