Search Results - "INNOCENTI, Gregory"
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Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma
Published in PloS one (06-01-2011)“…Cholangiocarcinoma, also known as bile duct cancer, is the second most common primary hepatic carcinoma with a median survival of less than 2 years. The…”
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Signaling networks assembled by oncogenic EGFR and c-Met
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-2008)“…A major question regarding the sensitivity of solid tumors to targeted kinase inhibitors is why some tumors respond and others do not. The observation that…”
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Identification of Anaplastic Lymphoma Kinase as a Potential Therapeutic Target in Ovarian Cancer
Published in Cancer research (Chicago, Ill.) (01-07-2012)“…Ovarian cancer is the leading cause of death from gynecologic cancer. Improvement in the clinical outcome of patients is likely to be achieved by the…”
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Mutation-Specific Antibodies for the Detection of EGFR Mutations in Non–Small-Cell Lung Cancer
Published in Clinical cancer research (01-05-2009)“…Purpose: Activating mutations within the tyrosine kinase domain of epidermal growth factor receptor (EGFR) are found in approximately 10% to 20% of…”
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Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential
Published in Scientific reports (22-08-2016)“…MUC1 is a shared tumor antigen expressed on >80% of human cancers. We completed the first prophylactic cancer vaccine clinical trial based on a non-viral…”
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Human anti-MUC1 antibodies elicited by a prophylactic cancer vaccine for CAR T cell immunotherapy
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Hypoglycosylated MUC1 is a tumor-associated protein that is expressed on over 80% of all human cancers including adenocarcinomas of the colon,…”
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