Search Results - "INKSTER, JAMES A"
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Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2020)“…The most common cause of acute lung injury is ischemia-reperfusion injury (IRI), during which mitochondrial damage occurs. We have previously demonstrated that…”
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2
A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy
Published in JACC. Basic to translational science (01-12-2019)“…[Display omitted] •Mitochondrial transplantation uses mitochondria isolated from the patient’s own body to replace or augment native mitochondria damaged by…”
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3
Magnetic Droplet Microfluidics as a Platform for the Concentration of [18F]Fluoride and Radiosynthesis of Sulfonyl [18F]Fluoride
Published in ACS applied materials & interfaces (17-06-2015)“…The radioisotope 18F is often considered the best choice for positron emission tomography (PET) owing to its desirable chemical and radiochemical properties…”
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4
The Non-Anhydrous, Minimally Basic Synthesis of the Dopamine D2 Agonist [18F]MCL-524
Published in Chemistry an international journal (01-09-2021)“…The dopamine D2 agonist MCL-524 is selective for the D2 receptor in the high-affinity state (D2high), and, therefore, the PET analogue, [18F]MCL-524, may…”
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5
Mitochondrial transplantation prolongs cold ischemia time in murine heart transplantation
Published in The Journal of heart and lung transplantation (01-01-2019)“…Cold ischemia time (CIT) causes ischemia‒reperfusion injury to the mitochondria and detrimentally effects myocardial function and tissue viability…”
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6
Sulfonyl Fluoride-Based Prosthetic Compounds as Potential 18F Labelling Agents
Published in Chemistry : a European journal (27-08-2012)“…Nucleophilic incorporation of [18F]F− under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the advent of…”
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7
Preclinical validations of [18F]FPyPEGCBT-c(RGDfK): a 18F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis
Published in EJNMMI radiopharmacy and chemistry (25-10-2016)“…Background α V β 3 , α V β 5 and α 5 β 1 integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to…”
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8
The Non-Anhydrous, Minimally Basic Synthesis of the Dopamine D 2 Agonist [18F]MCL-524
Published in Chemistry an international journal (01-09-2021)“…The dopamine D agonist MCL-524 is selective for the D receptor in the high-affinity state (D ), and, therefore, the PET analogue, [ F]MCL-524, may facilitate…”
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9
Labeling of an Antisense Oligonucleotide with [18F]FPy5yne
Published in Nucleosides, nucleotides & nucleic acids (01-11-2009)“…Functional imaging of gene expression in vivo with short-lived positron emitter 18 F remains an unrealized goal, in part because the long reaction times and…”
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10
Radiosynthesis and bioconjugation of [18F]FPy5yne, a prosthetic group for the 18F labeling of bioactive peptides
Published in Journal of labelled compounds & radiopharmaceuticals (01-11-2008)“…A new 18F‐based prosthetic group has been prepared for the labeling of azide‐modified peptides for use in PET imaging. 2‐[18F]fluoro‐3‐(hex‐5‐ynyloxy)pyridine…”
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11
A novel 2-cyanobenzothiazole-based (18)F prosthetic group for conjugation to 1,2-aminothiol-bearing targeting vectors
Published in Organic & biomolecular chemistry (28-03-2015)“…In a bid to find an efficient means to radiolabel biomolecules under mild conditions for PET imaging, a bifunctional (18)F prosthetic molecule has been…”
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12
Abstract 14991: Mitochondrial Transplantation by Intraarterial Injection Ameliorates Acute Kidney Injury
Published in Circulation (New York, N.Y.) (17-11-2020)“…IntroductionAcute kidney injury (AKI) is a common clinical disorder and one of the major causes of morbidity and mortality during the postoperative period. In…”
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13
Sulfonyl Fluoride‐Based Prosthetic Compounds as Potential 18 F Labelling Agents
Published in Chemistry : a European journal (27-08-2012)“…Nucleophilic incorporation of [ 18 F]F − under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the advent of…”
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14
Preclinical validations of [ 18 F]FPyPEGCBT- c (RGDfK): a 18 F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis
Published in EJNMMI radiopharmacy and chemistry (2017)“…α β , α β and α β integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to healthy tissues; thereby they…”
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15
Radiosynthesis and bioconjugation of [ 18 F]FPy5yne, a prosthetic group for the 18 F labeling of bioactive peptides
Published in Journal of labelled compounds & radiopharmaceuticals (01-11-2008)“…A new 18 F‐based prosthetic group has been prepared for the labeling of azide‐modified peptides for use in PET imaging. 2‐[ 18…”
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16
Sulfonyl Fluoride-Based Prosthetic Compounds as Potential super(18)F Labelling Agents
Published in Chemistry : a European journal (01-08-2012)“…Nucleophilic incorporation of [ super(18)F]F super(-) under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the…”
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17
POSTDECISION DISSONANCE AT POST TIME
Published in Journal of personality and social psychology (01-04-1968)“…INVESTIGATED POSTDECISIONAL DISSONANCE REDUCTION PROCESSES FOLLOWING A COMMITMENT TO BET ON A HORSE IN THE NATURAL SETTING OF A RACE TRACK. IN EXP. 1, 69 $2…”
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