Search Results - "INGHAM, E"

Comparison of the biomechanical tensile and compressive properties of decellularised and natural porcine meniscus by Abdelgaied, A, Stanley, M, Galfe, M, Berry, H, Ingham, E, Fisher, J

“…Abstract Meniscal repair is widely used as a treatment for meniscus injury. However, where meniscal damage has progressed such that repair is not possible,…”
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Review of the biomechanics and biotribology of osteochondral grafts used for surgical interventions in the knee by Bowland, Philippa, Ingham, E, Jennings, Louise, Fisher, John

“…A review of research undertaken to evaluate the biomechanical stability and biotribological behaviour of osteochondral grafts in the knee joint and a brief…”
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The effect of nano- and micron-sized particles of cobalt–chromium alloy on human fibroblasts in vitro by Papageorgiou, I, Brown, C, Schins, R, Singh, S, Newson, R, Davis, S, Fisher, J, Ingham, E, Case, C.P

“…Abstract Wear debris from metal on polyethylene joint replacements causes asceptic loosening as a result of an inflammatory reaction of macrophages to…”
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Influence of the meniscus on friction and degradation of cartilage in the natural knee joint by McCann, L, Ingham, E, Jin, Z, Fisher, J

“…Summary Background Total meniscectomy has been shown to cause early-onset arthritis in the underlying cartilage and bone in the knee joint, demonstrating that…”
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Development of a preclinical natural porcine knee simulation model for the tribological assessment of osteochondral grafts in vitro by Bowland, P., Ingham, E., Fisher, J., Jennings, L.M.

“…In order to pre-clinically evaluate the performance and efficacy of novel osteochondral interventions, physiological and clinically relevant whole joint…”
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Biological reactions to wear debris in total joint replacement by Ingham, E, Fisher, J

“…The vast majority of total hip prostheses currently implanted consist of a hard metal or ceramic femoral head articulating against an ultra-high molecular…”
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Analysis of wear, wear particles, and reduced inflammatory potential of vitamin E ultrahigh-molecular-weight polyethylene for use in total joint replacement by Bladen, C. L., Teramura, S., Russell, S. L., Fujiwara, K., Fisher, J., Ingham, E., Tomita, N., Tipper, J. L.

“…Vitamin E (VE) has been added to ultrahigh‐molecular‐weight polyethylene (UHMWPE) acetabular cups and tibial trays primarily to reduce oxidative damage to the…”
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Volcanic records of the Laschamp geomagnetic excursion from Mt Ruapehu, New Zealand by Ingham, E., Turner, G.M., Conway, C.E., Heslop, D., Roberts, A.P., Leonard, G., Townsend, D., Calvert, A.

“…We present palaeodirectional records of the Laschamp geomagnetic excursion from lavas on Mt Ruapehu, New Zealand. Fourteen lava flows on the northwestern and…”
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On the design and efficacy assessment of self‐assembling peptide‐based hydrogel‐glycosaminoglycan mixtures for potential repair of early stage cartilage degeneration by Barco, A., Ingham, E., Fisher, J., Fermor, H., Davies, R.P.W.

“…Peptide‐based hydrogels are of interest for their potential use in regenerative medicine. Combining these hydrogels with materials that may enhance their…”
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Non-destructive monitoring of viability in an ex vivo organ culture model of osteochondral tissue by Elson, K M, Fox, N, Tipper, J L, Kirkham, J, Hall, R M, Fisher, J, Ingham, E

“…Organ culture is an increasingly important tool in research, with advantages over monolayer cell culture due to the inherent natural environment of tissues…”
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Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness by Sood, A., Salih, S., Roh, D., Lacharme-Lora, L., Parry, M., Hardiman, B., Keehan, R., Grummer, R., Winterhager, E., Gokhale, P. J., Andrews, P. W., Abbott, C., Forbes, K., Westwood, M., Aplin, J. D., Ingham, E., Papageorgiou, I., Berry, M., Liu, J., Dick, A. D., Garland, R. J., Williams, N., Singh, R., Simon, A. K., Lewis, M., Ham, J., Roger, L., Baird, D. M., Crompton, L. A., Caldwell, M. A., Swalwell, H., Birch-Machin, M., Lopez-Castejon, G., Randall, A., Lin, H., Suleiman, M-S., Evans, W. H., Newson, R., Case, C. P.

“…The use of nanoparticles in medicine is ever increasing, and it is important to understand their targeted and non-targeted effects. We have previously shown…”
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Comparison of the cytotoxicity of clinically relevant cobalt–chromium and alumina ceramic wear particles in vitro by Germain, M.A., Hatton, A., Williams, S., Matthews, J.B., Stone, M.H., Fisher, J., Ingham, E.

“…Concern over polyethylene wear particle induced aseptic loosening of metal-on-polyethylene hip prostheses has led to renewed interest in alternative materials…”
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Effect of nominal stress on the long term friction, deformation and wear of native and glycosaminoglycan deficient articular cartilage by Katta, J, Jin, Z, Ingham, E, Fisher, J

“…Summary Objectives Earlier in vitro studies have shown that the coefficient of friction (COF) of cartilage decreases with increasing load at the lower end of…”
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Impact of Globodera ellingtonae on yield of potato (Solanum tuberosum) by Zasada, Inga A., Ingham, Russell E., Baker, Hannah, Phillips, Wendy S.

“…was described from Oregon and Idaho in 2012. Due to the close phylogenetic relationship of this nematode to the potato cyst nematodes and , and evidence that…”
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Influence of hyaluronic acid on the time-dependent friction response of articular cartilage under different conditions by Bell, C J, Ingham, E, Fisher, J

“…Therapeutic lubricant injections of hyaluronic acid are a relatively recent treatment for osteoarthritis. Their efficacy, however, in vivo has been subject to…”
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Thresholds for indirect DNA damage across cellular barriers for orthopaedic biomaterials by Parry, Michael C, Bhabra, Gevdeep, Sood, Aman, Machado, Filipa, Cartwright, Laura, Saunders, Margaret, Ingham, E, Newson, R, Blom, Ashley W, Case, Charles P

“…Abstract Cobalt–chromium particles and ions can induce indirect DNA damage and chromosome aberrations in human cells on the other side of a cellular barrier in…”
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Isolation and characterization of UHMWPE wear particles down to ten nanometers in size from in vitro hip and knee joint simulators by Tipper, J.L., Galvin, A.L., Williams, S., McEwen, H.M.J., Stone, M.H., Ingham, E., Fisher, J.

“…There is currently considerable interest in the wear debris and osteolytic potential of different types of bearings used in total joint replacements. The…”
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In vitro biomechanical and hydrodynamic characterisation of decellularised human pulmonary and aortic roots by Desai, A, Vafaee, T, Rooney, P, Kearney, J N, Berry, H E, Ingham, E, Fisher, J, Jennings, L M

“…The use of decellularised biological heart valves in the replacement of damaged heart valves offers a promising solution to reduce the degradation issues…”
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The effect of hyaluronic acid and phospholipid based lubricants on friction within a human cartilage damage model by Forsey, Richard W., Fisher, John, Thompson, Jonathan, Stone, Martin H., Bell, Carol, Ingham, Eileen

“…The lubricating abilities of different formulations of high molecular weight hyaluronic acid (HA), dipalmitoyl phosphatidylcholine (DPCC) and mixtures of both…”
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An investigation of the effect of conformity of knee hemiarthroplasty designs on contact stress, friction and degeneration of articular cartilage: A tribological study by McCann, L, Ingham, E, Jin, Z, Fisher, J

“…Abstract Hemiarthroplasty is a potentially attractive alternative to knee replacement for young, active patients, as it allows preservation of more bone stock…”
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