Search Results - "INDRAJIT NANDA"

Dynamics of vertebrate sex chromosome evolution: from equal size to giants and dwarfs by Schartl, Manfred, Schmid, Michael, Nanda, Indrajit

“…The Y and W chromosomes of mammals and birds are known to be small because most of their genetic content degenerated and were lost due to absence of…”
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Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion by Lekszas, Caroline, Foresti, Ombretta, Raote, Ishier, Liedtke, Daniel, König, Eva-Maria, Nanda, Indrajit, Vona, Barbara, De Coster, Peter, Cauwels, Rita, Malhotra, Vivek, Haaf, Thomas

“…The transport and Golgi organization 1 (TANGO1) proteins play pivotal roles in the secretory pathway. Full length TANGO1 is a transmembrane protein localised…”
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Genetics of Tinnitus: Still in its Infancy by Vona, Barbara, Nanda, Indrajit, Shehata-Dieler, Wafaa, Haaf, Thomas

“…Tinnitus is the perception of a phantom sound that affects between 10 and 15% of the general population. Despite this considerable prevalence, treatments for…”
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Epigenetic signatures of gestational diabetes mellitus on cord blood methylation by Haertle, Larissa, El Hajj, Nady, Dittrich, Marcus, Müller, Tobias, Nanda, Indrajit, Lehnen, Harald, Haaf, Thomas

“…Intrauterine exposure to gestational diabetes mellitus (GDM) confers a lifelong increased risk for metabolic and other complex disorders to the offspring…”
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Genetic and epigenetic changes in clonal descendants of irradiated human fibroblasts by Flunkert, Julia, Maierhofer, Anna, Dittrich, Marcus, Müller, Tobias, Horvath, Steve, Nanda, Indrajit, Haaf, Thomas

“…To study delayed genetic and epigenetic radiation effects, which may trigger radiation-induced carcinogenesis, we have established single-cell clones from…”
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A RAD-tag genetic map for the platyfish (Xiphophorus maculatus) reveals mechanisms of karyotype evolution among teleost fish by Amores, Angel, Catchen, Julian, Nanda, Indrajit, Warren, Wesley, Walter, Ron, Schartl, Manfred, Postlethwait, John H

“…Mammalian genomes can vary substantially in haploid chromosome number even within a small taxon (e.g., 3-40 among deer alone); in contrast, teleost fish…”
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Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes by Maierhofer, Anna, Flunkert, Julia, Oshima, Junko, Martin, George M., Poot, Martin, Nanda, Indrajit, Dittrich, Marcus, Müller, Tobias, Haaf, Thomas

“…Werner Syndrome (WS) is an adult‐onset segmental progeroid syndrome. Bisulfite pyrosequencing of repetitive DNA families revealed comparable blood DNA…”
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Analysis of global DNA methylation changes in primary human fibroblasts in the early phase following X-ray irradiation by Maierhofer, Anna, Flunkert, Julia, Dittrich, Marcus, Müller, Tobias, Schindler, Detlev, Nanda, Indrajit, Haaf, Thomas

“…Epigenetic alterations may contribute to the generation of cancer cells in a multi-step process of tumorigenesis following irradiation of normal body cells…”
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Whole-Genome Sequencing Identified New Structural Variations in the DMD Gene That Cause Duchenne Muscular Dystrophy in Two Girls by Pluta, Natalie, von Moers, Arpad, Pechmann, Astrid, Stenzel, Werner, Goebel, Hans-Hilmar, Atlan, David, Wolf, Beat, Nanda, Indrajit, Zaum, Ann-Kathrin, Rost, Simone

“…Dystrophinopathies are the most common muscle diseases, especially in men. In women, on the other hand, a manifestation of Duchenne muscular dystrophy is rare…”
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Targeted next-generation sequencing of deafness genes in hearing-impaired individuals uncovers informative mutations by Vona, Barbara, Müller, Tobias, Nanda, Indrajit, Neuner, Cordula, Hofrichter, Michaela A. H., Schröder, Jörg, Bartsch, Oliver, Läßig, Anne, Keilmann, Annerose, Schraven, Sebastian, Kraus, Fabian, Shehata-Dieler, Wafaa, Haaf, Thomas

“…Purpose: Targeted next-generation sequencing provides a remarkable opportunity to identify variants in known disease genes, particularly in extremely…”
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Detection of pericentric inversion with breakpoint in DMD by whole genome sequencing by Zaum, Ann‐Kathrin, Nanda, Indrajit, Kress, Wolfram, Rost, Simone

“…Background Dystrophinopathies caused by variants in the DMD gene are a well‐studied muscle disease. The most common type of variant in DMD are large deletions…”
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A Duplicated Copy of DMRT1 in the Sex-Determining Region of the Y Chromosome of the Medaka, Oryzias latipes by Nanda, Indrajit, Kondo, Mariko, Hornung, Ute, Asakawa, Shuichi, Winkler, Christoph, Shimizu, Atsushi, Shan, Zhihong, Haaf, Thomas, Shimizu, Nobuyoshi, Shima, Akihiro, Schmid, Michael, Schartl, Manfred

“…The genes that determine the development of the male or female sex are known in Caenorhabditis elegans, Drosophila, and most mammals. In many other organisms…”
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Confirmation of GRHL2 as the gene for the DFNA28 locus by Vona, Barbara, Nanda, Indrajit, Neuner, Cordula, Müller, Tobias, Haaf, Thomas

“…More than 10 years ago, a c.1609_1610insC mutation in the grainyhead‐like 2 (GRHL2) gene was identified in a large family with nonsyndromic sensorineural…”
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Evolution of the Degenerated Y-Chromosome of the Swamp Guppy, Micropoecilia picta by Nanda, Indrajit, Schories, Susanne, Simeonov, Ivan, Adolfi, Mateus Contar, Du, Kang, Steinlein, Claus, Alsheimer, Manfred, Haaf, Thomas, Schartl, Manfred

“…The conspicuous colour sexual dimorphism of guppies has made them paradigmatic study objects for sex-linked traits and sex chromosome evolution. Both the X-…”
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Genetic Characterization of Rat Hepatic Stellate Cell Line HSC-T6 for In Vitro Cell Line Authentication by Nanda, Indrajit, Steinlein, Claus, Haaf, Thomas, Buhl, Eva M, Grimm, Domink G, Friedman, Scott L, Meurer, Steffen K, Schröder, Sarah K, Weiskirchen, Ralf

“…Immortalized hepatic stellate cells (HSCs) established from mouse, rat, and humans are valuable in vitro models for the biomedical investigation of liver…”
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Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka by Kondo, Mariko, Hornung, Ute, Nanda, Indrajit, Imai, Shuichiro, Sasaki, Takashi, Shimizu, Atsushi, Asakawa, Shuichi, Hori, Hiroshi, Schmid, Michael, Shimizu, Nobuyoshi, Schartl, Manfred

“…Sequencing of the human Y chromosome has uncovered the peculiarities of the genomic organization of a heterogametic sex chromosome of old evolutionary age, and…”
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Genetic Characterization of Rat Hepatic Stellate Cell Line PAV-1 by Gäberlein, Kiara, Schröder, Sarah K, Nanda, Indrajit, Steinlein, Claus, Haaf, Thomas, Buhl, Eva M, Sauvant, Patrick, Sapin, Vincent, Abergel, Armand, Weiskirchen, Ralf

“…The rat hepatic stellate cell line PAV-1 was established two decades ago and proposed as a cellular model to study aspects of hepatic retinoic acid metabolism…”
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Hereditary hearing loss SNP-microarray pilot study by Vona, Barbara, Hofrichter, Michaela A H, Schröder, Jörg, Shehata-Dieler, Wafaa, Nanda, Indrajit, Haaf, Thomas

“…Despite recent advancements in diagnostic tools, the genomic landscape of hereditary hearing loss remains largely uncharacterized. One strategy to understand…”
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Rat Hepatic Stellate Cell Line CFSC-2G: Genetic Markers and Short Tandem Repeat Profile Useful for Cell Line Authentication by Nanda, Indrajit, Schröder, Sarah K, Steinlein, Claus, Haaf, Thomas, Buhl, Eva M, Grimm, Domink G, Weiskirchen, Ralf

“…Hepatic stellate cells (HSCs) are also known as lipocytes, fat-storing cells, perisinusoidal cells, or Ito cells. These liver-specific mesenchymal cells…”
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Roles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafish by Rodríguez-Marí, Adriana, Wilson, Catherine, Titus, Tom A, Cañestro, Cristian, BreMiller, Ruth A, Yan, Yi-Lin, Nanda, Indrajit, Johnston, Adam, Kanki, John P, Gray, Erin M, He, Xinjun, Spitsbergen, Jan, Schindler, Detlev, Postlethwait, John H

“…Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate…”
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