Search Results - "INDELICATO, J. M"

The acylating potential of .gamma.-lactam antibacterials: base hydrolysis of bicyclic pyrazolidinones by Indelicato, Joseph M, Pasini, Carol E

“…The acylating ability of the gamma-lactam ring of a new class of antibacterial agent, the bicyclic pyrazolidinones 1, was compared to that of the beta-lactam…”
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Comparative reactivity of 1-carba-1-dethiacephalosporins with cephalosporins by Blaszczak, Larry C, Brown, Raymond F, Cook, Gwendolyn K, Hornback, William J, Indelicato, Joseph M, Jordan, Chris L, Katner, Alan S, Kinnick, Michael D, McDonald, John H

“…Nine matched pairs of cephalosporins and their 1-carba-1-dethiacephalosporin analogues have been compared with regard to microbiological activity, beta-lactam…”
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Synthesis, hydrolysis rates, supercomputer modeling, and antibacterial activity of bicyclic tetrahydropyridazinones by Jungheim, Louis N, Boyd, Donald B, Indelicato, Joseph M, Pasini, Carol E, Preston, David A, Alborn, William E

“…Bicyclic tetrahydropyridazinones, such as 13, where X are strongly electron-withdrawing groups, were synthesized to investigate their antibacterial activity…”
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3-Sulfonyl-1-carba-1-dethiacephems by Crowell, Thomas A., Halliday, Basil D., McDonald, John H., Indelicato, Joseph M., Pasini, Carol E., Wu, Ernie C. Y.

“…The stability of the 1-carba-1-dethiacephalosporin framework has allowed the synthesis of a range of 3-sulfonyl-1-carba-1-dethiacephems unavailable for a…”
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Heteroatom-activated .beta.-lactam antibiotics: considerations of differences in the biological activity of [[3(S)-(acylamino)-2-oxo-1-azetidinyl]oxy]acetic acids (oxamazins) and the corresponding sulfur analogs (thiamazins) by Boyd, Donald B, Eigenbrot, Charles, Indelicato, Joseph M, Miller, Marvin J, Pasini, Carol E, Woulfe, Steven R

“…The considerable antibacterial activity of [[3(S)-(acylamino)-2-oxo-1-azetidinyl]oxy]acetic acids (oxamazins) in contrast to the lack of activity of the…”
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3-Quaternary ammonium 1-carba-1-dethiacephems by Cook, Gwendolyn K., McDonald, John H., Alborn, William, Boyd, Donald B., Eudaly, Judy A., Indelicato, Joseph M., Johnson, Rod, Kasher, Jeffrey S., Pasini, Carol E.

“…A series of structurally unique 1-carba-1-dethiacephems is described. The structural stability of the 1-carba-1-dethiacephem nucleus was essential for the…”
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Cephalothin: hydrolysis of the C-3'-acetoxy moiety of a 7-aminocephalosporanic acid; observation of both acyl-oxygen bond cleavage and reversible alkyl-oxygen bond cleavage by Indelicato, J M, Engel, G L, Occolowitz, J L

“…The aqueous solution chemistry of the C-3'-acetoxy moiety of cephalothin sodium (1b) was examined with the use of isotopically labeled H2(18)O and…”
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Pharmaceutical properties of loracarbef: the remarkable solution stability of an oral 1-carba-1-dethiacephalosporin antibiotic by Pasini, C E, Indelicato, J M

“…Loracarbef is an oral 1-carba-1-dethiacephalosporin antibiotic structurally related to cefaclor. Like many beta-lactam antibiotics, loracarbef exists in…”
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The Pediatric Proton and Photon Therapy Comparison Cohort: Study Design for a Multicenter Retrospective Cohort to Investigate Subsequent Cancers After Pediatric Radiation Therapy by Berrington de González, Amy, Gibson, Todd M., Lee, Choonsik, Albert, Paul S., Griffin, Keith T., Kitahara, Cari Meinhold, Liu, Danping, Mille, Matthew M., Shin, Jungwook, Bajaj, Benjamin V.M., Flood, Tristin E., Gallotto, Sara L., Paganetti, Harald, Ahmed, Safia K., Eaton, Bree R., Indelicato, Daniel J., Milgrom, Sarah A., Palmer, Joshua D., Baliga, Sujith, Poppe, Matthew M., Tsang, Derek S., Wong, Kenneth, Yock, Torunn I.

“…The physical properties of protons lower doses to surrounding normal tissues compared with photons, potentially reducing acute and long-term adverse effects,…”
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Clinical Outcomes Following Dose-Escalated Proton Therapy for Skull-Base Chordoma by Holtzman, Adam L., Rotondo, Ronny L., Rutenberg, Michael S., Indelicato, Daniel J., De Leo, Alexandra, Rao, Dinesh, Patel, Jeet, Morris, Christopher G., Mendenhall, William M.

“…PURPOSETo evaluate the effectiveness of external-beam proton therapy (PT) on local control and survival in patients with skull-base chordoma. MATERIALS AND…”
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A Prospective Outcomes Study of Proton Therapy for Chordomas and Chondrosarcomas of the Spine by Indelicato, Daniel J., MD, Rotondo, Ronny L., MD, Begosh-Mayne, Dustin, MD, Scarborough, Mark T., MD, Gibbs, C. Parker, MD, Morris, Christopher G., MS, Mendenhall, William M., MD

“…Purpose To evaluate the effectiveness of definitive or adjuvant external beam proton therapy on survival in patients with chordomas and chondrosarcomas of the…”
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Treatment Guidelines for Preoperative Radiation Therapy for Retroperitoneal Sarcoma: Preliminary Consensus of an International Expert Panel by Baldini, Elizabeth H., MD, MPH, Wang, Dian, MD, PhD, Haas, Rick L.M., MD, PhD, Catton, Charles N., MD, Indelicato, Daniel J., MD, Kirsch, David G., MD, PhD, Roberge, David, MD, Salerno, Kilian, MD, Deville, Curtiland, MD, Guadagnolo, B. Ashleigh, MD, MPH, O'Sullivan, Brian, MD, Petersen, Ivy A., MD, Le Pechoux, Cecile, MD, PhD, Abrams, Ross A., MD, DeLaney, Thomas F., MD, PhD

“…Purpose Evidence for external beam radiation therapy (RT) as part of treatment for retroperitoneal sarcoma (RPS) is limited. Preoperative RT is the subject of…”
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Spatial Agreement of Brainstem Dose Distributions Depending on Biological Model in Proton Therapy for Pediatric Brain Tumors by Fjæra, Lars Fredrik, Indelicato, Daniel J., Ytre-Hauge, Kristian S., Muren, Ludvig P., Lassen-Ramshad, Yasmin, Toussaint, Laura, Dahl, Olav, Stokkevåg, Camilla H.

“…During radiation therapy for pediatric brain tumors, the brainstem is a critical organ at risk, possibly with different radio-sensitivity across its…”
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Reducing Anesthesia and Health Care Cost Through Utilization of Child Life Specialists in Pediatric Radiation Oncology by Scott, Michael T., MD, MBA, Todd, Kimberly E., CCLS, Oakley, Heather, LCSW, Bradley, Julie A., MD, Rotondo, Ronny L., MD, Morris, Christopher G., MS, Klein, Stuart, MBA, Mendenhall, Nancy P., MD, Indelicato, Daniel J., MD

“…Purpose To analyze the effectiveness of a certified child life specialist (CCLS) in reducing the frequency of daily anesthesia at our institution, and to…”
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Hydrolysis of 3-chloro-3-cephems. Intramolecular nucleophilic attack in cefaclor by Indelicato, J M, Dinner, A, Peters, L R, Wilham, W L

“…The chemical reactivity of 3-chloro-3-cephems was found to be similar to that of the correspondingly substituted 7-aminocephalosporanic acids and 12-13 times…”
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Consensus Report From the Stockholm Pediatric Proton Therapy Conference by Indelicato, Daniel J., MD, Merchant, Thomas, DO, PhD, Laperriere, Normand, MD, FRCPC, Lassen, Yasmin, MD, PhD, Vennarini, Sabina, MD, Wolden, Suzanne, MD, FACR, Hartsell, William, MD, Pankuch, Mark, PhD, Brandal, Petter, MD, PhD, Law, Chi-Ching K., MD, Taylor, Roger, MD, Laskar, Siddhartha, MD, Okcu, Mehmet Fatih, MD, MPH, Bouffet, Eric, MD, Mandeville, Henry, MBChB, MRCP, FRCR, MD, Björk-Eriksson, Thomas, MD, PhD, Nilsson, Kristina, MD, PhD, Nyström, Hakan, PhD, Constine, Louis Sandy, MD, Story, Michael, PhD, Timmermann, Beate, MD, Roberts, Kenneth, MD, Kortmann, Rolf-Dieter, MD

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Pulmonary Toxicity Following Proton Therapy for Thoracic Lymphoma by Nanda, Ronica, MD, Flampouri, Stella, PhD, Mendenhall, Nancy P., MD, Indelicato, Daniel J., MD, Jones, Lisa M., MD, Seeram, Vandana K., MD, Hoppe, Bradford S., MD, MPH

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Patterns of Failure in Pediatric Rhabdomyosarcoma Following Proton Therapy by Vern-Gross, Tamara Z., DO, FAAP, Indelicato, Daniel J., MD, Bradley, Julie A., MD, Rotondo, Ronny L., MD

“…Abstract Purpose We report on the patterns of failure in children with rhabdomyosarcoma treated with proton therapy. Patients and Methods Between February 2007…”
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Retroperitoneal Sarcoma Target Volume and Organ at Risk Contour Delineation Agreement Among NRG Sarcoma Radiation Oncologists by Baldini, Elizabeth H., MD, MPH, Abrams, Ross A., MD, Bosch, Walter, DSc, Roberge, David, MD, Haas, Rick L.M., MD, PhD, Catton, Charles N., MD, Indelicato, Daniel J., MD, Olsen, Jeffrey R., MD, Deville, Curtiland, MD, Chen, Yen-Lin, MD, Finkelstein, Steven E., MD, DeLaney, Thomas F., MD, PhD, Wang, Dian, MD, PhD

“…Purpose The purpose of this study was to evaluate the variability in target volume and organ at risk (OAR) contour delineation for retroperitoneal sarcoma…”
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Azetidinone imides by SPRY, D. O, SNYDER, N. J, BHALA, A. R, PASINI, C. E, INDELICATO, J. M

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