Search Results - "INAMURA, KAZUE"

Dibasic (Amidinoaryl)propanoic Acid Derivatives as Novel Blood Coagulation Factor Xa Inhibitors by Nagahara, Takayasu, Yokoyama, Yukio, Inamura, Kazue, Katakura, Shin-ichi, Komoriya, Satoshi, Yamaguchi, Hitoshi, Hara, Tsuyoshi, Iwamoto, Masahiro

“…Since activated factor X (FXa) is a coagulant enzyme that generates thrombin and participates in both intrinsic and extrinsic coagulation pathways, inhibition…”
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DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITIES OF ORALLY ACTIVE COAGULATION FACTOR Xa INHIBITORS by Nagahara, Takayasu, Katakura, Shin-ichi, Yokoyama, Yukio, Kanaya, Naoaki, Inamura, Kazue, Komoriya, Satoshi, Yamada, Kohji, Yamaguchi, Hitoshi, Tanabe, Kiyoshi, Morishima, Yoshiyuki, Ishihara, Hiroaki, Hara, Tsuyoshi, Yamazaki, Ken-ichi, Kunitada, Satoshi, Iwamoto, Masahiro

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Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites by Komoriya, Satoshi, Kanaya, Naoaki, Nagahara, Takayasu, Yokoyama, Asako, Inamura, Kazue, Yokoyama, Yukio, Katakura, Shin-ichi, Hara, Tsuyoshi

“…Compound 38 exhibited a high activity toward factor Xa and also showed prolongation of APTT after oral administration in rat. Since factor Xa (fXa) plays a…”
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Cyclic Guanidines. XVI. Synthesis and Biological Activities of Tetracyclic Imidazo [2, 1-b] quinazolinone Derivatives by ISHIKAWA, FUMIYOSHI, YAMAGUCHI, HITOSHI, SAEGUSA, JUNJI, INAMURA, KAZUE, MIMURA, TETSUYA, NISHI, TOSHIYUKI, SAKUMA, KYOKO, ASHIDA, SHINICHIRO

“…Tetracyclic imidazo [2, 1-b] quinazolinone derivatives (18) with a modified or unmodified alkylene chain were prepared and evaluated for their ability to…”
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Cyclic guanidines. 17. Novel (N-substituted amino)imidazo[2,1-b]quinazolin-2-ones: water-soluble platelet aggregation inhibitors by Ishikawa, Fumiyoshi, Saegusa, Junji, Inamura, Kazue, Sakuma, Kyoko, Ashida, Shinichiro

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Cyclic guanidines. 17. Novel (N-substituted amino)imidazo[2,1-b]quinazolin-2 ones: water-soluble platelet aggregation inhibitors by Ishikawa, F, Saegusa, J, Inamura, K, Sakuma, K, Ashida, S

“…A series of novel 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-one derivatives substituted with a secondary amino group has been prepared and tested for the…”
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Effects of arginine derivatives on soluble guanylate cyclase from neuroblastoma N1E 115 cells by Yoshioka, M, Fujimori, H, Deguchi, T, Masayasu, H, Suzuki, K, Inamura, K, Kosasayama, A, Ishikawa, F

“…The effects of L-arginine (Arg) derivatives on soluble guanylate cyclase from neuroblastoma N1E 115 cells were examined. The Arg derivatives were modified at…”
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