Search Results - "INAKA, KOJI"

Dynamic interactions in the l-lactate oxidase active site facilitate substrate binding at pH4.5 by Furubayashi, Naoki, Inaka, Koji, Kamo, Masayuki, Umena, Yasufumi, Matsuoka, Takeshi, Morimoto, Yukio

“…The crystal structure of l-lactate oxidase in complex with l-lactate was solved at a 1.33 Å resolution. The electron density of the bound l-lactate was clearly…”
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Crystal structure of the PX domain of Vps17p from Saccharomyces cerevisiae by Obita, Takayuki, Inaka, Koji, Kohda, Daisuke, Maita, Nobuo

“…The structure determination of the PX (phox homology) domain of the Saccharomyces cerevisiae Vps17p protein presented a challenging case for molecular…”
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Highly Purified Glucose Isomerase Crystals under Microgravity Conditions Grow as Fast as Those on the Ground Do by Suzuki, Yoshihisa, Ninomiya, Ai, Fukuyama, Seijiro, Shimaoka, Taro, Nagai, Masae, Inaka, Koji, Yanagiya, Shin-ichiro, Sone, Takehiko, Wachi, Shingo, Kawaguchi, Satoshi, Arai, Yasutomo, Tsukamoto, Katsuo

“…Suppression of convection flows (solute transportation) and suppression of impurity incorporation into crystals seem to be the main reasons why the quality of…”
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Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies by Takaya, Daisuke, Inaka, Koji, Omura, Akifumi, Takenuki, Kenji, Kawanishi, Masashi, Yabuki, Yukako, Nakagawa, Yukari, Tsuganezawa, Keiko, Ogawa, Naoko, Watanabe, Chiduru, Honma, Teruki, Aritake, Kosuke, Urade, Yoshihiro, Shirouzu, Mikako, Tanaka, Akiko

“…[Display omitted] Hematopoietic prostaglandin D synthase (H-PGDS) is one of the two enzymes that catalyze prostaglandin D2 synthesis and a potential…”
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Crystal Structure of Chitinase ChiW from Paenibacillus sp. str. FPU-7 Reveals a Novel Type of Bacterial Cell-Surface-Expressed Multi-Modular Enzyme Machinery by Itoh, Takafumi, Hibi, Takao, Suzuki, Fumiko, Sugimoto, Ikumi, Fujiwara, Akihiro, Inaka, Koji, Tanaka, Hiroaki, Ohta, Kazunori, Fujii, Yutaka, Taketo, Akira, Kimoto, Hisashi

“…The Gram-positive bacterium Paenibacillus sp. str. FPU-7 effectively hydrolyzes chitin by using a number of chitinases. A unique chitinase with two catalytic…”
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Methods for Obtaining Better Diffractive Protein Crystals: From Sample Evaluation to Space Crystallization by Hashizume, Yoshinobu, Inaka, Koji, Furubayashi, Naoki, Kamo, Masayuki, Takahashi, Sachiko, Tanaka, Hiroaki

“…In this paper, we present a summary on how to obtain protein crystals from which better diffraction images can be produced. In particular, we describe, in…”
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Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase by Sakamoto, Yasumitsu, Suzuki, Yoshiyuki, Nakamura, Akihiro, Watanabe, Yurie, Sekiya, Mizuki, Roppongi, Saori, Kushibiki, Chisato, Iizuka, Ippei, Tani, Osamu, Sakashita, Hitoshi, Inaka, Koji, Tanaka, Hiroaki, Yamada, Mitsugu, Ohta, Kazunori, Honma, Nobuyuki, Shida, Yosuke, Ogasawara, Wataru, Nakanishi-Matsui, Mayumi, Nonaka, Takamasa, Gouda, Hiroaki, Tanaka, Nobutada

“…Antimicrobial resistance is a global public threat and raises the need for development of new antibiotics with a novel mode of action. The dipeptidyl peptidase…”
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Novel Device and Strategy for Growing Large, High-Quality Protein Crystals by Controlling Crystallization Conditions by Tanigawa, Naoki, Takahashi, Sachiko, Yan, Bin, Kamo, Masayuki, Furubayashi, Naoki, Kubota, Koji, Inaka, Koji, Tanaka, Hiroaki

“…Neutron diffraction experiments are informative for determining the locations of hydrogen atoms in protein molecules; however, much larger crystals are needed…”
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Microgravity environment grown crystal structure information based engineering of direct electron transfer type glucose dehydrogenase by Okuda-Shimazaki, Junko, Yoshida, Hiromi, Lee, Inyoung, Kojima, Katsuhiro, Suzuki, Nanoha, Tsugawa, Wakako, Yamada, Mitsugu, Inaka, Koji, Tanaka, Hiroaki, Sode, Koji

“…The heterotrimeric flavin adenine dinucleotide dependent glucose dehydrogenase is a promising enzyme for direct electron transfer (DET) principle-based glucose…”
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High-Quality Protein Crystal Growth of Mouse Lipocalin-Type Prostaglandin D Synthase in Microgravity by Inaka, Koji, Takahashi, Sachiko, Aritake, Kosuke, Tsurumura, Toshiharu, Furubayashi, Naoki, Yan, Bin, Hirota, Erika, Sano, Satoshi, Sato, Masaru, Kobayashi, Tomoyuki, Yoshimura, Yoshinori, Tanaka, Hiroaki, Urade, Yoshihiro

“…Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) catalyzes the isomerization of PGH2 to PGD2 and is involved in the regulation of pain and of nonrapid eye…”
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High-resolution X-ray crystal structure of bovine H-protein using the high-pressure cryocooling method by Higashiura, Akifumi, Ohta, Kazunori, Masaki, Mika, Sato, Masaru, Inaka, Koji, Tanaka, Hiroaki, Nakagawa, Atsushi

“…Recently, many technical improvements in macromolecular X‐ray crystallography have increased the number of structures deposited in the Protein Data Bank and…”
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JAXA protein crystallization in space: ongoing improvements for growing high-quality crystals by Takahashi, Sachiko, Ohta, Kazunori, Furubayashi, Naoki, Yan, Bin, Koga, Misako, Wada, Yoshio, Yamada, Mitsugu, Inaka, Koji, Tanaka, Hiroaki, Miyoshi, Hiroshi, Kobayashi, Tomoyuki, Kamigaichi, Shigeki

“…The Japan Aerospace Exploration Agency (JAXA) started a high‐quality protein crystal growth project, now called JAXA PCG, on the International Space Station…”
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Crystallographic analysis of FAD-dependent glucose dehydrogenase by Komori, Hirofumi, Inaka, Koji, Furubayashi, Naoki, Honda, Michinari, Higuchi, Yoshiki

“…An FAD‐dependent glucose dehydrogenase (GDH) from Aspergillus terreus was purified and crystallized at 293 K using the sitting‐drop vapour‐diffusion method. A…”
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Phase-diagram-guided method for growth of a large crystal of glycoside hydrolase family 45 inverting cellulase suitable for neutron structural analysis by Nakamura, Akihiko, Ishida, Takuya, Fushinobu, Shinya, Kusaka, Katsuhiro, Tanaka, Ichiro, Inaka, Koji, Higuchi, Yoshiki, Masaki, Mika, Ohta, Kazunori, Kaneko, Satoshi, Niimura, Nobuo, Igarashi, Kiyohiko, Samajima, Masahiro

“…Neutron protein crystallography (NPC) is a powerful tool for determining the hydrogen position and water orientation in proteins, but a much larger protein…”
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Structural insight into the stereoselective production of PGF2α by Old Yellow Enzyme from Trypanosoma cruzi by Okamoto, Naoki, Yamaguchi, Keishi, Mizohata, Eiichi, Tokuoka, Keiji, Uchiyama, Nahoko, Sugiyama, Shigeru, Matsumura, Hiroyoshi, Inaka, Koji, Urade, Yoshihiro, Inoue, Tsuyoshi

“…Old yellow enzyme (OYE) is an NADPH oxidoreductase capable of reducing a variety of compounds. It contains flavin mononucleotide (FMN) as a prosthetic group. A…”
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An archetypical extradiol-cleaving catecholic dioxygenase: the crystal structure of catechol 2,3-dioxygenase (metapyrocatechase) from Pseudomonas putida mt-2 by Kita, Akiko, Kita, Shin-ichi, Fujisawa, Ikuhide, Inaka, Koji, Ishida, Tetsuo, Horiike, Kihachiro, Nozaki, Mitsuhiro, Miki, Kunio

“…Background: Catechol dioxygenases catalyze the ring cleavage of catechol and its derivatives in either an intradiol or extradiol manner. These enzymes have a…”
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Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment by Tanaka, Hiroaki, Tsurumura, Toshiharu, Aritake, Kosuke, Furubayashi, Naoki, Takahashi, Sachiko, Yamanaka, Mari, Hirota, Erika, Sano, Satoshi, Sato, Masaru, Kobayashi, Tomoyuki, Tanaka, Tetsuo, Inaka, Koji, Urade, Yoshihiro

“…Human hematopoietic prostaglandin synthase, one of the better therapeutic target enzymes for allergy and inflammation, was crystallized with 22 inhibitors and…”
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Optimization of salt concentration in PEG-based crystallization solutions by Yamanaka, Mari, Inaka, Koji, Furubayashi, Naoki, Matsushima, Masaaki, Takahashi, Sachiko, Tanaka, Hiroaki, Sano, Satoshi, Sato, Masaru, Kobayashi, Tomoyuki, Tanaka, Tetsuo

“…Although polyethylene glycol (PEG) is the most widely used precipitant in protein crystallization, the concentration of co‐existing salt in the solution has…”
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Effects of different anti-tau antibodies on tau fibrillogenesis: RTA-1 and RTA-2 counteract tau aggregation by Taniguchi, Taizo, Sumida, Miho, Hiraoka, Shuko, Tomoo, Koji, Kakehi, Tomoko, Minoura, Katsuhiko, Sugiyama, Shigeru, Inaka, Koji, Ishida, Toshimasa, Saito, Naoaki, Tanaka, Chikako

“…Tau is the major antigenic component of neurofibrillary pathology in tauopathy, including Alzheimer’s disease. Although conversion of soluble tau to an…”
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Numerical Analysis of the Depletion Zone Formation Around a Growing Protein Crystal by TANAKA, HIROAKI, INAKA, KOJI, SUGIYAMA, SHIGERU, TAKAHASHI, SACHIKO, SANO, SATOSHI, SATO, MASARU, YOSHITOMI, SUSUMU

“…: It is expected that a protein depletion zone and an impurity depletion zone are formed around a crystal during protein crystal growth if the diffusion field…”
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