Search Results - "IMRICH, R"

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  1. 1

    Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria by Ranganath, L. R., Milan, A. M., Hughes, A. T., Davison, A. S., M, Khedr, Norman, B. P., Bou-Gharios, G., Gallagher, J. A., Imrich, R., Arnoux, J. B., Rudebeck, M., Olsson, B.

    Published in Scientific reports (27-09-2022)
    “…Nitisinone (NIT) produces inevitable but varying degree of tyrosinaemia. However, the understanding of the dynamic adaptive relationships within the tyrosine…”
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  2. 2

    Anthropometric, Body Composition, and Nutritional Indicators with and without Nutritional Intervention during Nitisinone Therapy in Alkaptonuria by Ranganath, L R, Khedr, M, Milan, A M, Davison, A S, Hughes, A T, Norman, B P, Bygott, H, Luangrath, E, Judd, S, Soulsby, C, Olsson, B, Imrich, R

    Published in Nutrients (15-08-2024)
    “…Protein nutrition disorder in alkaptonuria (AKU), resulting in increased homogentisic acid (HGA) before nitisinone therapy and increased tyrosine (TYR) during…”
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  3. 3

    Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project by Braconi, D., Giustarini, D., Marzocchi, B., Peruzzi, L., Margollicci, M., Rossi, R., Bernardini, G., Millucci, L., Gallagher, J.A., Le Quan Sang, K.-H., Imrich, R., Rovensky, J., Al-Sbou, M., Ranganath, L.R., Santucci, A.

    Published in Osteoarthritis and cartilage (01-08-2018)
    “…The aim of this work was to assess baseline serum levels of established biomarkers related to inflammation and oxidative stress in samples from alkaptonuric…”
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  4. 4

    Joint replacement risk is markedly increased in alkaptonuria (AKU) in those with prior arthroplasty by Ranganath, L.R., Khedr, M., Norman, B.P., Hughes, J.H., Imrich, R., Arnoux, J.B., Olsson, B., Rudebeck, M., Gallagher, J.A., Bou-Gharios, G.

    Published in Molecular genetics and metabolism reports (01-09-2024)
    “…Increased homogentisic acid (HGA) in alkaptonuria (AKU) causes severe arthritis. Nitisinone reduces the production of HGA, but whether it also decreases…”
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  5. 5

    Carbohydrate-Based Chiral Iodoarene Catalysts: A Survey through the Development of an Improved Catalyst Design by Imrich, Michael R, Biehler, Linda E, Maichle-Mössmer, Cäcilia, Ziegler, Thomas

    Published in Molecules (Basel, Switzerland) (28-10-2019)
    “…Iodoarene catalysts can be applied in versatile reactions, for instance in the construction of complex chiral molecules via dearomatization of simple aromatic…”
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  6. 6

    Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria by Ranganath, L R, Hughes, A T, Davison, A S, Khedr, M, Olsson, B, Rudebeck, M, Imrich, R, Norman, B P, Bou-Gharios, G, Gallagher, J A, Milan, A M

    Published in Molecular genetics and metabolism (01-06-2022)
    “…Adaptations within the phenylalanine (PHE)/tyrosine (TYR) pathway during nitisinone (NIT) are not fully understood. To characterise the temporal changes in…”
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  7. 7

    Nutritional intervention as an essential part of multiple sclerosis treatment? by Penesová, A, Dean, Z, Kollár, B, Havranová, A, Imrich, R, Vlček, M, Rádiková, Ž

    Published in Physiological research (01-01-2018)
    “…Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. In addition to the genetic, epigenetic and…”
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  8. 8

    Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria by Ranganath, L.R., Milan, A.M., Hughes, A.T., Davison, A.S., Khedr, M., Norman, B.P., Bou-Gharios, G., Gallagher, J.A., Gornall, M., Jackson, R., Imrich, R., Rovensky, J., Rudebeck, M., Olsson, B.

    Published in Molecular genetics and metabolism reports (01-03-2022)
    “…Although changes in the tyrosine pathway during nitisinone therapy are known, a complete characterization of the induced tyrosinaemia is lacking to improve…”
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  9. 9

    D-Fructose-based spiro-fused PHOX ligands: synthesis and application in enantioselective allylic alkylation by Imrich, Michael R, Kraft, Jochen, Maichle-Mössmer, Cäcilia, Ziegler, Thomas

    Published in Beilstein journal of organic chemistry (08-08-2018)
    “…Phosphinooxazoline (PHOX) ligands are an important class of ligands in asymmetric catalysis. We synthesized ten novel D-fructose-derived spiro-fused PHOX…”
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  10. 10

    Autonomic Nervous System Function in Newly Diagnosed Multiple Sclerosis: Association With Lipid Levels and Insulin Resistance by Hardoňová, M, Šiarnik, P, Siváková, M, Suchá, M, Vlček, M, Imrich, R, Turčáni, P, Havranová, A, Rádiková, Ž, Žitňanová, I, Dean, Z, Penesová, A, Kollár, B

    Published in Physiological research (30-12-2021)
    “…Autonomic nervous system (ANS) disorders are common in multiple sclerosis (MS). Previous studies showed differences in insulin resistance (IR) and lipoprotein…”
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  11. 11

    Insulin sensitivity indices: a proposal of cut-off points for simple identification of insulin-resistant subjects by Radikova, Z, Koska, J, Huckova, M, Ksinantova, L, Imrich, R, Vigas, M, Trnovec, T, Langer, P, Sebokova, E, Klimes, I

    “…Demanding measurement of insulin sensitivity using clamp methods does not simplify the identification of insulin resistant subjects in the general population…”
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  12. 12

    Exercise associated hormonal signals as powerful determinants of an effective fat mass loss by Bajer, B, Vlcek, M, Galusova, A, Imrich, R, Penesova, A

    Published in Endocrine regulations (Bratislava) (01-07-2015)
    “…Obesity management for achieving an effective weight loss includes dietary modification and exercise [resistance (strength), endurance (cardiovascular) or…”
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  13. 13

    Arthropathy in Acromegaly by Killinger, Z., MD, PhD, Payer, J., MD, PhD, Lazúrová, I., MD, PhD, Imrich, R., MD, PhD, Homérová, Z., MD, Kužma, M., MD, Rovenský, J., MD, DSc, FRCP

    “…Articular involvement in acromegaly is one of the most frequent clinical complications and may be present as the earliest symptom in a significant proportion…”
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  14. 14

    Genetics of neuroendocrine factors in rheumatoid arthritis by Mravcova, M, Chovanova, L, Paulikova, L, Vlcek, M, Rovensky, J, Killinger, Z, Wendl, J, Imrich, R

    Published in Hormone and metabolic research (01-06-2015)
    “…Inadequate production of cortisol related to inflammation and decrease in adrenal androgen production are hallmarks of hypothalamic-pituitary-adrenal…”
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  15. 15

    Autoimmune rheumatic diseases and Klinefelter syndrome Autoimunitné reumatické choroby a Klinefelterov syndróm by Lazúrová, I., Rovenský, J., Imrich, R., Blažíčková, S., Lazúrová, Z., Payer, J.

    Published in EUROPEAN PHARMACEUTICAL JOURNAL (01-12-2016)
    “…Abstract The article summarizes data on the association of Klinefelter syndrome (KS) with autoimmune rheumatic diseases, that is rheumatoid arthritis (RA),…”
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  16. 16

    Obesogenic and diabetogenic impact of high organochlorine levels (HCB, p,p'-DDE, PCBs) on inhabitants in the highly polluted Eastern Slovakia by Langer, P, Ukropec, J, Kocan, A, Drobna, B, Radikova, Z, Huckova, M, Imrich, R, Gasperikova, D, Klimes, I, Trnovec, T

    Published in Endocrine regulations (Bratislava) (01-01-2014)
    “…This study was aimed to evaluate possible obesogenic and diabetogenic impact of highly increased serum level of persistent organochlorinated pollutants POPs,…”
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    Neurocirculatory and nigrostriatal abnormalities in Parkinson disease from LRRK2 mutation by GOLDSTEIN, D. S, IMRICH, R, PECKHAM, E, HOLMES, C, LOPEZ, G, CREWS, C, HARDY, J, SINGLETON, A, HALLETT, M

    Published in Neurology (16-10-2007)
    “…Patients with Parkinson disease (PD) often have cardiac sympathetic denervation and failure of neurocirculatory regulation by baroreflexes. Familial PD caused…”
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  19. 19

    Rheumatic diseases and Klinefelter's syndrome by Rovenský, J., Imrich, R., Lazúrová, I., Payer, J.

    Published in Annals of the New York Academy of Sciences (01-04-2010)
    “…The article summarizes reports on the concurrence of Klinefelter's syndrome (KS) with inflammatory rheumatic diseases, rheumatoid arthritis (RA), juvenile…”
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  20. 20

    Determinants of adrenal androgen hypofunction in premenopausal females with rheumatoid arthritis by Imrich, R, Vlcek, M, Kerlik, J, Vogeser, M, Kirchhoff, F, Penesova, A, Radikova, Z, Lukac, J, Rovensky, J

    Published in Physiological research (01-01-2014)
    “…The aim of our study was to investigate adrenocortical function in the context of disease activity and inflammatory status in premenopausal RA females. Adrenal…”
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