Search Results - "IMRICH, R"
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1
Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria
Published in Scientific reports (27-09-2022)“…Nitisinone (NIT) produces inevitable but varying degree of tyrosinaemia. However, the understanding of the dynamic adaptive relationships within the tyrosine…”
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2
Anthropometric, Body Composition, and Nutritional Indicators with and without Nutritional Intervention during Nitisinone Therapy in Alkaptonuria
Published in Nutrients (15-08-2024)“…Protein nutrition disorder in alkaptonuria (AKU), resulting in increased homogentisic acid (HGA) before nitisinone therapy and increased tyrosine (TYR) during…”
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3
Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project
Published in Osteoarthritis and cartilage (01-08-2018)“…The aim of this work was to assess baseline serum levels of established biomarkers related to inflammation and oxidative stress in samples from alkaptonuric…”
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4
Joint replacement risk is markedly increased in alkaptonuria (AKU) in those with prior arthroplasty
Published in Molecular genetics and metabolism reports (01-09-2024)“…Increased homogentisic acid (HGA) in alkaptonuria (AKU) causes severe arthritis. Nitisinone reduces the production of HGA, but whether it also decreases…”
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5
Carbohydrate-Based Chiral Iodoarene Catalysts: A Survey through the Development of an Improved Catalyst Design
Published in Molecules (Basel, Switzerland) (28-10-2019)“…Iodoarene catalysts can be applied in versatile reactions, for instance in the construction of complex chiral molecules via dearomatization of simple aromatic…”
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6
Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria
Published in Molecular genetics and metabolism (01-06-2022)“…Adaptations within the phenylalanine (PHE)/tyrosine (TYR) pathway during nitisinone (NIT) are not fully understood. To characterise the temporal changes in…”
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7
Nutritional intervention as an essential part of multiple sclerosis treatment?
Published in Physiological research (01-01-2018)“…Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. In addition to the genetic, epigenetic and…”
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Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria
Published in Molecular genetics and metabolism reports (01-03-2022)“…Although changes in the tyrosine pathway during nitisinone therapy are known, a complete characterization of the induced tyrosinaemia is lacking to improve…”
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9
D-Fructose-based spiro-fused PHOX ligands: synthesis and application in enantioselective allylic alkylation
Published in Beilstein journal of organic chemistry (08-08-2018)“…Phosphinooxazoline (PHOX) ligands are an important class of ligands in asymmetric catalysis. We synthesized ten novel D-fructose-derived spiro-fused PHOX…”
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10
Autonomic Nervous System Function in Newly Diagnosed Multiple Sclerosis: Association With Lipid Levels and Insulin Resistance
Published in Physiological research (30-12-2021)“…Autonomic nervous system (ANS) disorders are common in multiple sclerosis (MS). Previous studies showed differences in insulin resistance (IR) and lipoprotein…”
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11
Insulin sensitivity indices: a proposal of cut-off points for simple identification of insulin-resistant subjects
Published in Experimental and clinical endocrinology & diabetes (01-05-2006)“…Demanding measurement of insulin sensitivity using clamp methods does not simplify the identification of insulin resistant subjects in the general population…”
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12
Exercise associated hormonal signals as powerful determinants of an effective fat mass loss
Published in Endocrine regulations (Bratislava) (01-07-2015)“…Obesity management for achieving an effective weight loss includes dietary modification and exercise [resistance (strength), endurance (cardiovascular) or…”
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13
Arthropathy in Acromegaly
Published in Rheumatic diseases clinics of North America (01-11-2010)“…Articular involvement in acromegaly is one of the most frequent clinical complications and may be present as the earliest symptom in a significant proportion…”
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14
Genetics of neuroendocrine factors in rheumatoid arthritis
Published in Hormone and metabolic research (01-06-2015)“…Inadequate production of cortisol related to inflammation and decrease in adrenal androgen production are hallmarks of hypothalamic-pituitary-adrenal…”
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15
Autoimmune rheumatic diseases and Klinefelter syndrome Autoimunitné reumatické choroby a Klinefelterov syndróm
Published in EUROPEAN PHARMACEUTICAL JOURNAL (01-12-2016)“…Abstract The article summarizes data on the association of Klinefelter syndrome (KS) with autoimmune rheumatic diseases, that is rheumatoid arthritis (RA),…”
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16
Obesogenic and diabetogenic impact of high organochlorine levels (HCB, p,p'-DDE, PCBs) on inhabitants in the highly polluted Eastern Slovakia
Published in Endocrine regulations (Bratislava) (01-01-2014)“…This study was aimed to evaluate possible obesogenic and diabetogenic impact of highly increased serum level of persistent organochlorinated pollutants POPs,…”
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Insulin resistance in young, lean male subjects with essential hypertension
Published in Journal of human hypertension (01-03-2014)Get full text
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18
Neurocirculatory and nigrostriatal abnormalities in Parkinson disease from LRRK2 mutation
Published in Neurology (16-10-2007)“…Patients with Parkinson disease (PD) often have cardiac sympathetic denervation and failure of neurocirculatory regulation by baroreflexes. Familial PD caused…”
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19
Rheumatic diseases and Klinefelter's syndrome
Published in Annals of the New York Academy of Sciences (01-04-2010)“…The article summarizes reports on the concurrence of Klinefelter's syndrome (KS) with inflammatory rheumatic diseases, rheumatoid arthritis (RA), juvenile…”
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Determinants of adrenal androgen hypofunction in premenopausal females with rheumatoid arthritis
Published in Physiological research (01-01-2014)“…The aim of our study was to investigate adrenocortical function in the context of disease activity and inflammatory status in premenopausal RA females. Adrenal…”
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