Search Results - "IMOTO, Koji"
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Trends Over Time in the Incidences of ST-Segment Elevation Myocardial Infarction and Non-ST-Segment Elevation Myocardial Infarction During the Past Decade in a Rural Japanese High-Aged Population
Published in Circulation Journal (25-01-2021)“…Background:In developed countries, the incidence of non-ST-segment elevation myocardial infarction (NSTEMI) has outpaced that of ST-segment elevation…”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients
Published in Canadian journal of gastroenterology & hepatology (2019)“…Aim. Immune checkpoint inhibitors (ICIs) have improved the survival rate of patients carrying various malignant neoplasms. Despite their efficacy, ICIs…”
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3
Clinicopathologic Features of Adult-onset Still's Disease Complicated by Severe Liver Injury
Published in Internal Medicine (15-02-2024)“…Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder. Severe liver injury has rarely been reported, although liver enzyme elevation is a…”
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4
Association Between Atrial High-Rate Episodes and Ischemic/Major Bleeding Events in Patients With a Cardiac Implantable Electronic Device ― A 10-Year, Single-Center Historical Cohort Study
Published in Circulation Journal (21-07-2021)“…Background:An association between atrial high-rate episode (AHRE) and stroke has been reported, although data for the Asian population are limited. This study…”
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5
Corticosteroid suppresses urea-cycle-related gene expressions in ornithine transcarbamylase deficiency
Published in BMC gastroenterology (28-03-2022)“…Ornithine transcarbamylase deficiency (OTCD) is most common among urea cycle disorders (UCDs), defined by defects in enzymes associated with ureagenesis…”
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Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma
Published in Canadian journal of gastroenterology & hepatology (2021)“…Objective. Metabolic alteration is widely considered as one of the hallmarks of cancer. Hepatocellular carcinoma (HCC) presents a unique pathological feature…”
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Fatal community-acquired Bacillus cereus pneumonia in an immunocompetent adult man: a case report
Published in BMC infectious diseases (27-02-2019)“…Bacillus cereus is a gram-positive rod bacterium that is responsible for food poisoning. It is naturally widely distributed, and thus often contaminates…”
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Microcirculatory disturbance in acute liver injury is triggered by IFNγ-CD40 axis
Published in Journal of inflammation (London, England) (21-06-2024)“…Acute liver failure (ALF) is a life-threatening disorder that progresses from self-limiting acute liver injury (ALI). Microcirculatory disturbance…”
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Microcirculatory disturbance in acute liver injury
Published in Experimental and therapeutic medicine (01-06-2021)“…Microcirculatory disturbance is thought to be involved in the pathogenesis of acute liver injury (ALI). The current study examined the pathophysiologic role of…”
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Incidence and risk factors for cardiac implantable electronic device infection in current clinical settings in a Japanese population: A 20-year single-center observational study
Published in Journal of cardiology (01-07-2020)“…•Revision and younger age were risk factors for cardiac implantable electronic device (CIED) infection.•Incidence of CIED infection was due to an increase in…”
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Upregulated expression of hypoxia reactive genes in peripheral blood mononuclear cells from chronic liver disease patients
Published in Biochemistry and biophysics reports (01-09-2021)“…Liver fibrosis induces intrahepatic microcirculation disorder and hypoxic stress. Hypoxic stress has the potential for an increase in the possibility of more…”
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The Efficacy of Tofogliflozin on Metabolic Dysfunction-Associated Fatty Liver Disease
Published in Gastroenterology insights (01-03-2022)“…The increasing number of patients with fatty liver disease is a major health problem. Fatty liver disease with metabolic dysfunction has been recognized as…”
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13
Recombinant human soluble thrombomodulin ameliorates acetaminophen-induced liver toxicity in mice
Published in Experimental and therapeutic medicine (01-08-2019)“…Recombinant human soluble thrombomodulin alpha (rhTM) has been developed as an anticoagulant with anti-inflammatory activity. Notably, acetaminophen (APAP)…”
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The Combination of Nucleotide Analog Therapy and Steroid Pulse Therapy for Acute HBV Infection Effectively Promotes HBV Clearance
Published in Gastroenterology insights (23-03-2022)“…Acute hepatitis B virus (HBV) infection occasionally progresses to acute liver failure, often with poor prognosis. The appropriate pharmacological approach is…”
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Purification and Characterization of a Liquefying α-Amylase from Alkalophilic Thermophilic Bacillus sp. AAH-31
Published in Bioscience, biotechnology, and biochemistry (2012)“…α-Amylase (EC 3.2.1.1) hydrolyzes an internal α-1,4-glucosidic linkage of starch and related glucans. Alkalophilic liquefying enzymes from Bacillus species are…”
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Incidence of Mid-Term Prognostic Events in Patients With Acute Coronary Syndrome During the Late 2010s in 2 Tertiary Hospitals in a Rural Area of Japan ― A Temporal Comparison
Published in Circulation Reports (10-05-2023)“…Background: Data on the incidence of mid-term prognostic events in patients who developed acute coronary syndrome (ACS) in the late 2010s are scarce.Methods…”
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Detection of Lipid-Laden Atherosclerotic Plaque by Wavelet Analysis of Radiofrequency Intravascular Ultrasound Signals
Published in Journal of the American College of Cardiology (01-06-2005)“…This study examined the feasibility of using a wavelet analysis of radiofrequency (RF) intravascular ultrasound (IVUS) signals in detecting lipid-laden plaque…”
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Longitudinal Structural Determinants of Atherosclerotic Plaque Vulnerability
Published in Journal of the American College of Cardiology (01-10-2005)“…Longitudinal Structural Determinants of Atherosclerotic Plaque Vulnerability: A Computational Analysis of Stress Distribution Using Vessel Models and…”
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Incidence and Demographic Trends for Acute Coronary Syndrome in a Non-Epidemic Area During the Coronavirus Disease Pandemic in Japan ― A 2-Institutional Observational Study
Published in Circulation Reports (10-02-2021)“…Background:We investigated the incidence of acute coronary syndrome (ACS) in a non-epidemic area of coronavirus disease-2019 (COVID-19) in Japan.Methods and…”
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Pirfenidone attenuates acetaminophen-induced liver injury via suppressing c-Jun N-terminal kinase phosphorylation
Published in Toxicology and applied pharmacology (01-01-2022)“…Acetaminophen (APAP)-induced liver injury is the most frequent cause of acute liver failure in Western countries. Pirfenidone (PFD), an orally bioavailable…”
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