Search Results - "IMERI, Luca"

How (and why) the immune system makes us sleep by Opp, Mark R, Imeri, Luca

“…Key Points Serotonin promotes wakefulness but is necessary for sleep. Cytokines, such as interleukin 1 (IL-1) and tumor necrosis factor, are involved in…”
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Doxycycline rescues recognition memory and circadian motor rhythmicity but does not prevent terminal disease in fatal familial insomnia mice by Lavigna, Giada, Masone, Antonio, Bouybayoune, Ihssane, Bertani, Ilaria, Lucchetti, Jacopo, Gobbi, Marco, Porcu, Luca, Zordan, Stefano, Rigamonti, Mara, Imeri, Luca, Restelli, Elena, Chiesa, Roberto

“…Fatal familial insomnia (FFI) is a dominantly inherited prion disease linked to the D178N mutation in the gene encoding the prion protein (PrP). Symptoms,…”
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Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease by Bouybayoune, Ihssane, Mantovani, Susanna, Del Gallo, Federico, Bertani, Ilaria, Restelli, Elena, Comerio, Liliana, Tapella, Laura, Baracchi, Francesca, Fernández-Borges, Natalia, Mangieri, Michela, Bisighini, Cinzia, Beznoussenko, Galina V, Paladini, Alessandra, Balducci, Claudia, Micotti, Edoardo, Forloni, Gianluigi, Castilla, Joaquín, Fiordaliso, Fabio, Tagliavini, Fabrizio, Imeri, Luca, Chiesa, Roberto

“…Fatal familial insomnia (FFI) and a genetic form of Creutzfeldt-Jakob disease (CJD178) are clinically different prion disorders linked to the D178N prion…”
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Humoral response to anti SARS-CoV2 vaccination at one and seven months is not different in shift workers and non-shift workers by Faioni, Elena M., Imeri, Luca, Bonomi, Alice, Galotta, Arianna, Guerra, Vanessa, Pase, Luca, Bianchi, Susanna, Biondi, Maria L.

“…Since previous studies, mostly performed in healthy adults, show that sleep restriction around time of vaccination impairs antibody response and shift work…”
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Mutant Prion Protein Expression Causes Motor and Memory Deficits and Abnormal Sleep Patterns in a Transgenic Mouse Model by Dossena, Sara, Imeri, Luca, Mangieri, Michela, Garofoli, Anna, Ferrari, Loris, Senatore, Assunta, Restelli, Elena, Balducci, Claudia, Fiordaliso, Fabio, Salio, Monica, Bianchi, Susanna, Fioriti, Luana, Morbin, Michela, Pincherle, Alessandro, Marcon, Gabriella, Villani, Flavio, Carli, Mirjana, Tagliavini, Fabrizio, Forloni, Gianluigi, Chiesa, Roberto

“…A familial form of Creutzfeldt-Jakob disease (CJD) is linked to the D178N/V129 prion protein (PrP) mutation. Tg(CJD) mice expressing the mouse homolog of this…”
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Thermoregulation as a non-unified system: A difficult to teach concept by Imeri, Luca

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Febrile and sleep responses to an immune challenge are affected by trait aggressiveness in rats by Statello, Rosario, Carnevali, Luca, Bianchi, Susanna, Sgoifo, Andrea, Imeri, Luca

“…•In high aggressive rats, an immune challenge induces a 24-h long fever.•In high aggressive rats, an immune challenge significantly increases NREM sleep…”
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Sleep inhibition induced by amyloid‐β oligomers is mediated by the cellular prion protein by Del Gallo, Federico, Bianchi, Susanna, Bertani, Ilaria, Messa, Massimo, Colombo, Laura, Balducci, Claudia, Salmona, Mario, Imeri, Luca, Chiesa, Roberto

“…Sleep is severely impaired in patients with Alzheimer's disease. Amyloid‐β deposition in the brain of Alzheimer's disease patients is a key event in its…”
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A Tribute to Mauro Mancia—1929 – 2007 by Imeri, Luca

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Sleep as a behavioral model of neuro-immune interactions by Opp, M R, Imeri, L

“…The central nervous system, by a variety of mechanisms engages in constant surveillance of the peripheral immune system. Alterations in the status of the…”
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Optimization of the High Order Correctors for HL-LHC Toward the Series Production by Statera, Marco, Alessandria, Franco, Bellomo, Giovanni, Broggi, Francesco, Imeri, Luca, Leone, Augusto, Mariotto, Samuele, Paccalini, Antonio, Pasini, Alessandro, Pedrini, Danilo, Prioli, Marco, Sorbi, Massimo, Todero, Maurizio, Uva, Carlo, Valente, Riccardo, Musso, Andrea, Todesco, Ezio, Campaniello, Marco, Canetti, Marco, Gangini, Fabrizio, Manini, Paolo, Santini, Carlo, Zanichelli, Alessandro

“…INFN is developing at the LASA lab (Milano, Italy) the High Order (HO) corrector magnets for the High Luminosity-LHC (HL-LHC) project, which will equip the…”
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Transgenic mice recapitulate the phenotypic heterogeneity of genetic prion diseases without developing prion infectivity: Role of intracellular PrP retention in neurotoxicity by Chiesa, Roberto, Restelli, Elena, Comerio, Liliana, Del Gallo, Federico, Imeri, Luca

“…Genetic prion diseases are degenerative brain disorders caused by mutations in the gene encoding the prion protein (PrP). Different PrP mutations cause…”
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Muscarinic receptor subtypes in the medial preoptic area and sleep-wake cycles by Imeri, L, Bianchi, S, Angeli, P, Mancia, M

“…To clarify which muscarinic receptor subtype(s) mediate changes in sleep and cortical temperature (Tcort) induced by carbachol microinjections into the medial…”
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Interleukin-1 Inhibits Putative Cholinergic Neurons in Vitro and REM Sleep when Microinjected into the Rat Laterodorsal Tegmental Nucleus by BRAMBILLA, Dario, BARAJON, Isabella, BIANCHI, Susanna, OPP, Mark R, IMERI, Luca

“…REM sleep is suppressed during infection, an effect mimicked by the administration of cytokines such as interleukin-1 (IL-1). In spite of this observation,…”
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Inhibition of caspase-1 in rat brain reduces spontaneous nonrapid eye movement sleep and nonrapid eye movement sleep enhancement induced by lipopolysaccharide by Imeri, Luca, Bianchi, Susanna, Opp, Mark R

“…Evidence suggests that IL-1beta is involved in promoting physiological nonrapid eye movement (NREM) sleep. IL-1beta has also been proposed to mediate NREM…”
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Effects of serotonergic activation by 5-hydroxytryptophan on sleep and body temperature of C57BL/6J and interleukin-6-deficient mice are dose and time related by Morrow, Jonathan D, Vikraman, Sundeep, Imeri, Luca, Opp, Mark R

“…Extensive data implicate serotonin (5-hydroxytryptamine [5-HT]) in the regulation of sleep. Jouvet has hypothesized that 5-HT promotes wakefulness, yet is…”
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Differential effects of M2 and M3 muscarinic antagonists on the sleep-wake cycle by Imeri, L, Bianchi, S, Angeli, P, Mancia, M

“…To study the role of muscarinic receptor subtypes in sleep control, methoctramine (25, 50, 75 micrograms), a highly selective M2 antagonist, was injected…”
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Interleukin-1β enhances non-rapid eye movement sleep when microinjected into the dorsal raphe nucleus and inhibits serotonergic neurons in vitro by Manfridi, Alfredo, Brambilla, Dario, Bianchi, Susanna, Mariotti, Maurizio, Opp, Mark R., Imeri, Luca

“…Interleukin‐1 (IL‐1) and IL‐1 receptors are constitutively expressed in normal brain. IL‐1 increases non‐rapid eye movements (NREM) sleep in several animal…”
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Transgenic Fatal Familial Insomnia Mice Indicate Prion Infectivity-Independent Mechanisms of Pathogenesis and Phenotypic Expression of Disease: e1004796 by Bouybayoune, Ihssane, Mantovani, Susanna, Gallo, Federico Del, Bertani, Ilaria, Restelli, Elena, Comerio, Liliana, Tapella, Laura, Baracchi, Francesca, Fernández-Borges, Natalia, Mangieri, Michela, Bisighini, Cinzia, Beznoussenko, Galina V, Paladini, Alessandra, Balducci, Claudia, Micotti, Edoardo, loni, Gianluigi, Castilla, Joaquín, Fiordaliso, Fabio, Tagliavini, Fabrizio, Imeri, Luca, Chiesa, Roberto

“…Fatal familial insomnia (FFI) and a genetic form of Creutzfeldt-Jakob disease (CJD178) are clinically different prion disorders linked to the D178N prion…”
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Interleukin-1β modulates state-dependent discharge activity of preoptic area and basal forebrain neurons: role in sleep regulation by Alam, Md. Noor, McGinty, Dennis, Bashir, Tariq, Kumar, Sunil, Imeri, Luca, Opp, Mark R., Szymusiak, Ronald

“…Interleukin‐1β (IL‐1) is a pro‐inflammatory cytokine that has been implicated in the regulation of nonrapid eye movement (nonREM) sleep. IL‐1, IL‐1 receptors…”
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