Search Results - "IMBALZANO, Anthony N"
-
1
Versatility of PRMT5-induced methylation in growth control and development
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-12-2011)“…Arginine methylation governs important cellular processes that impact growth and proliferation, as well as differentiation and development. Through their…”
Get full text
Journal Article -
2
Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells
Published in Genome Biology (28-09-2015)“…Higher-order chromatin structure is often perturbed in cancer and other pathological states. Although several genetic and epigenetic differences have been…”
Get full text
Journal Article -
3
Temporal regulation of chromatin during myoblast differentiation
Published in Seminars in cell & developmental biology (01-12-2017)“…The commitment to and execution of differentiation programmes involves a significant change in gene expression in the precursor cell to facilitate development…”
Get full text
Journal Article -
4
Calcineurin Broadly Regulates the Initiation of Skeletal Muscle-Specific Gene Expression by Binding Target Promoters and Facilitating the Interaction of the SWI/SNF Chromatin Remodeling Enzyme
Published in Molecular and cellular biology (01-10-2019)“…Calcineurin (Cn) is a calcium-activated serine/threonine protein phosphatase that is broadly implicated in diverse cellular processes, including the regulation…”
Get full text
Journal Article -
5
RUNX1‐dependent mechanisms in biological control and dysregulation in cancer
Published in Journal of cellular physiology (01-06-2019)“…The RUNX1 transcription factor has recently been shown to be obligatory for normal development. RUNX1 controls the expression of genes essential for proper…”
Get full text
Journal Article -
6
SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells
Published in Genome research (01-09-2016)“…The packaging of DNA into chromatin plays an important role in transcriptional regulation and nuclear processes. Brahma-related gene-1 SMARCA4 (also known as…”
Get full text
Journal Article -
7
The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer
Published in Epigenomics (01-06-2017)“…Mammalian SWI/SNF enzymes are ATP-dependent remodelers of chromatin structure. These multisubunit enzymes are heterogeneous in composition; there are two…”
Get full text
Journal Article -
8
Brg1 Controls the Expression of Pax7 to Promote Viability and Proliferation of Mouse Primary Myoblasts
Published in Journal of cellular physiology (01-12-2015)“…Brg1 (Brahma‐related gene 1) is a catalytic component of the evolutionarily conserved mammalian SWI/SNF ATP‐dependent chromatin remodeling enzymes that disrupt…”
Get full text
Journal Article -
9
Differential Contributions of mSWI/SNF Chromatin Remodeler Sub-Families to Myoblast Differentiation
Published in International journal of molecular sciences (09-07-2023)“…Mammalian SWI/SNF (mSWI/SNF) complexes are ATP-dependent chromatin remodeling enzymes that are critical for normal cellular functions. mSWI/SNF enzymes are…”
Get full text
Journal Article -
10
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells
Published in Biochimica et biophysica acta (01-11-2016)“…RUNX1 is a transcription factor functioning both as an oncogene and a tumor suppressor in breast cancer. RUNX1 alters chromatin structure in cooperation with…”
Get full text
Journal Article -
11
Promotion of adipogenesis by JMJD6 requires the AT hook-like domain and is independent of its catalytic function
Published in PloS one (20-08-2019)“…JMJD6 is a member of the Jumonji C domain containing enzymes that demethylate and/or hydroxylate substrate proteins. It is a multi-functional protein that has…”
Get full text
Journal Article -
12
Regulation of the Wnt signaling pathway during myogenesis by the mammalian SWI/SNF ATPase BRG1
Published in Frontiers in cell and developmental biology (07-07-2023)“…Skeletal muscle differentiation is a tightly regulated process, and the importance of the mammalian SWI/SNF (mSWI/SNF) chromatin remodeling family for…”
Get full text
Journal Article -
13
Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition
Published in The Journal of biological chemistry (10-11-2017)“…Transcriptional regulation is modulated in part by chromatin-remodeling enzymes that control gene accessibility by altering chromatin compaction or nucleosome…”
Get full text
Journal Article -
14
Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections
Published in PloS one (06-02-2013)“…Changes in nuclear morphology occur during normal development and have been observed during the progression of several diseases. The shape of a nucleus is…”
Get full text
Journal Article -
15
Mitotic Gene Bookmarking: An Epigenetic Program to Maintain Normal and Cancer Phenotypes
Published in Molecular cancer research (01-11-2018)“…Reconfiguration of nuclear structure and function during mitosis presents a significant challenge to resume the next cell cycle in the progeny cells without…”
Get full text
Journal Article -
16
CK2-Dependent Phosphorylation of the Brg1 Chromatin Remodeling Enzyme Occurs during Mitosis
Published in International journal of molecular sciences (30-01-2020)“…Brg1 (Brahma-related gene 1) is one of two mutually exclusive ATPases that can act as the catalytic subunit of mammalian SWI/SNF (mSWI/SfigureNF) chromatin…”
Get full text
Journal Article -
17
The Protein Arginine Methyltransferase Prmt5 Is Required for Myogenesis because It Facilitates ATP-Dependent Chromatin Remodeling
Published in Molecular and Cellular Biology (01-01-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
18
Distinct Protein Arginine Methyltransferases Promote ATP-Dependent Chromatin Remodeling Function at Different Stages of Skeletal Muscle Differentiation
Published in Molecular and Cellular Biology (01-04-2009)“…Author's Correction ( vol. 33 , p. 4618 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
Get full text
Journal Article -
19
C-ing the Genome: A Compendium of Chromosome Conformation Capture Methods to Study Higher-Order Chromatin Organization
Published in Journal of cellular physiology (01-01-2016)“…Three‐dimensional organization of the chromatin has important roles in transcription, replication, DNA repair, and pathologic events such as translocations…”
Get full text
Journal Article -
20
p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
Published in Nature genetics (01-07-2004)“…During skeletal myogenesis, genomic reprogramming toward terminal differentiation is achieved by recruiting chromatin-modifying enzymes to muscle-specific…”
Get full text
Journal Article