Search Results - "IMANISHI, Masahito"
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The angiotensin II receptor-neprilysin inhibitor LCZ696 attenuates the progression of proteinuria in type 2 diabetic rats
Published in Journal of pharmacological sciences (01-03-2020)“…We examined the effects of the angiotensin receptor-neprilysin inhibitor LCZ696 on overt proteinuria and renal injury in type 2 diabetic Otsuka-Long-…”
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Oxidative stress/angiotensinogen/renin-angiotensin system axis in patients with diabetic nephropathy
Published in International journal of molecular sciences (21-11-2013)“…Although recent studies have proven that renin-angiotensin system (RAS) blockades retard the progression of diabetic nephropathy, the detailed mechanisms of…”
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3
A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes
Published in PloS one (19-12-2018)“…To explore novel genetic loci for diabetic nephropathy, we performed genome-wide association studies (GWAS) for diabetic nephropathy in Japanese patients with…”
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Tonsillectomy has beneficial effects on remission and progression of IgA nephropathy independent of steroid therapy
Published in Nephrology, dialysis, transplantation (01-07-2012)“…Indication of tonsillectomy in IgA nephropathy is controversial. The purpose of this study was to examine the efficacy of tonsillectomy on remission and…”
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Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats
Published in PloS one (18-09-2014)“…A growing body of evidence indicates that renal tissue injuries are reversible. We investigated whether dietary salt reduction with the combination therapy of…”
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Genetic Variations in the Gene Encoding ELMO1 Are Associated With Susceptibility to Diabetic Nephropathy
Published in Diabetes (New York, N.Y.) (01-04-2005)“…Genetic Variations in the Gene Encoding ELMO1 Are Associated With Susceptibility to Diabetic Nephropathy Atsuyuki Shimazaki 1 , Yoshihiro Kawamura 1 , Akio…”
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The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes
Published in PloS one (16-01-2013)“…Several linkage analyses have mapped a susceptibility locus for diabetic nephropathy to chromosome 18q22-23, and polymorphisms within the carnosine dipeptidase…”
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Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes
Published in Clinical and experimental nephrology (01-06-2011)“…Background Sirtuin is a member of the nicotinamide adenine dinucleotide (NAD)-dependent deacetylases, and has been reported to play a pivotal role in energy…”
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A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes
Published in PLoS genetics (01-02-2010)“…It has been suggested that genetic susceptibility plays an important role in the pathogenesis of diabetic nephropathy. A large-scale genotyping analysis of…”
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Churg-Strauss Syndrome Concomitant with Chronic Symmetrical Dacryoadenitis Suggesting Mikulicz's Disease
Published in Internal Medicine (01-01-2012)“…A case of Churg-Strauss syndrome complicated by chronic symmetrical dacryoadenitis suggestive of Mikulicz's disease is herein presented. A 72-year-old Japanese…”
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Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats
Published in The Journal of pharmacology and experimental therapeutics (01-03-2010)“…Treatment with angiotensin II type 1 receptor blockers (ARBs) is the first-line therapy for hypertensive patients with diabetic nephropathy. However, emerging…”
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12
Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases
Published in PloS one (18-02-2014)“…We have reported that toll-like receptor 4 (TLR4) and one of its endogenous ligands, myeloid-related protein 8 (MRP8 or S100A8), play an important role in the…”
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13
A Case of IgG4-Related Multifocal Fibrosclerosis Complicated by Central Diabetes Insipidus
Published in ENDOCRINE JOURNAL (2008)“…A 55-years-old man was admitted to our hospital with a 6-month history of general fatigue, purulent nasal discharge, polyuria, and polydipsia. Endocrinological…”
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Detailed localization of augmented angiotensinogen mRNA and protein in proximal tubule segments of diabetic kidneys in rats and humans
Published in International journal of biological sciences (01-01-2014)“…In the intrarenal renin-angiotensin system, angiotensinogen levels are well known to be increased in diabetes, and these enhanced intrarenal angiotensinogen…”
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15
Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic nephropathy in Japanese patients with type 2 diabetes
Published in Clinical and experimental nephrology (01-12-2013)“…Background A recent genome-wide association study for diabetic nephropathy in European type 1 diabetes identified 3 candidate loci for diabetic nephropathy. In…”
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16
Tubulointerstitial nephritis and uveitis (TINU) syndrome caused by the Chinese herb “Goreisan”
Published in Clinical and experimental nephrology (01-02-2009)“…A 58-year-old man was admitted to our hospital complaining of fever and arthralgia. His clinical course and marked ciliary hyperemia led us to suspect…”
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Japan Diabetic Nephropathy Cohort Study: study design, methods, and implementation
Published in Clinical and experimental nephrology (01-12-2013)“…Background Diabetic nephropathy, leading to end-stage renal disease, has a considerable impact on public health and the social economy. However, there are few…”
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Evidence for Abundant Presence of Chymase-Positive Mast Cells in the Kidneys of Patients with Immunoglobulin A Nephropathy: Effect of Combination Therapy with Prednisolone and Angiotensin II Receptor Blocker Valsartan
Published in Hypertension research (01-08-2008)“…Several investigators have reported chymase-positive mast cells in tubulointerstitial damage. However, the significance of the presence of chymase in the…”
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Effects of Benidipine on Glomerular Hemodynamics and Proteinuria in Patients with Nondiabetic Nephropathy
Published in Hypertension Research (01-07-2002)“…Experimental studies suggest that some long-acting calcium antagonists decrease glomerular hypertension and suppress the progression of nephropathy, but…”
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Sodium Sensitivity Related to Albuminuria Appearing Before Hypertension in Type 2 Diabetic Patients
Published in Diabetes care (01-01-2001)“…Sodium Sensitivity Related to Albuminuria Appearing Before Hypertension in Type 2 Diabetic Patients Masahito Imanishi , MD , Katsunobu Yoshioka , MD , Michiaki…”
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