Search Results - "IMAMIYA, Eiko"

Synthesis and Angiotensin II Receptor Antagonistic Activities of Benzimidazole Derivatives Bearing Acidic Heterocycles as Novel Tetrazole Bioisosteres by Kohara, Yasuhisa, Kubo, Keiji, Imamiya, Eiko, Wada, Takeo, Inada, Yoshiyuki, Naka, Takehiko

“…The design, synthesis, and biological activity of benzimidazole-7-carboxylic acids bearing 5-oxo-1,2,4-oxadiazole, 5-oxo-1,2,4-thiadiazole,…”
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Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of benzimidazolecarboxylic acids by Kubo, Keiji, Kohara, Yasuhisa, Imamiya, Eiko, Sugiura, Yoshihiro, Inada, Yoshiyuki, Furukawa, Yoshiyasu, Nishikawa, Kohei, Naka, Takehiko

“…A series of 2-substituted-1-[(biphenyl-4-yl)methyl]-1H-benzimidazole-7- carboxylic acids was prepared from the key intermediate 3-amino-2-[[(biphenyl-4-…”
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Novel, Non-acylguanidine-type Na+/H+ Exchanger Inhibitors:  Synthesis and Pharmacology of 5-Tetrahydroquinolinylidene Aminoguanidine Derivatives by Fukumoto, Shoji, Imamiya, Eiko, Kusumoto, Keiji, Fujiwara, Shuji, Watanabe, Toshifumi, Shiraishi, Mitsuru

“…In the course of our research into new types of non-acylguanidine Na+/H+ exchanger (NHE) inhibitors, we designed and synthesized aryl-fused…”
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Synthesis and Antitumor Activity of New Alkylphospholipids Containing Modifications of the Phosphocholine Moiety by UKAWA, Kiyoshi, IMAMIYA, Eiko, YAMAMOTO, Hiroaki, MIZUNO, Katsutoshi, TASAKA, Akihiro, TERASHITA, Zen-ichi, OKUTANI, Tetsuya, NOMURA, Hiroaki, KASUKABE, Takashi, HOZUMI, Motoo, KUDO, Ichiro, INOUE, Keizo

“…New antitumor alkylglycerophospholipids, in which primarily the phosphocholine moiety of the platelet activating factor (PAF) molecule was modified, were…”
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Studies on Antidiabetic Agents. III. 5-Arylthiazolidine-2, 4-diones as Potent Aldose Reductase Inhibitors by SOHDA, TAKASHI, MIZUNO, KATSUTOSHI, IMAMIYA, EIKO, TAWADA, HIROYUKI, MEGURO, KANJI, KAWAMATSU, YUTAKA, YAMAMOTO, YUJIRO

“…Thiazolidine-2, 4-dione derivatives having one or two substituent (s) such as phenyl, heteryl and alkyl group (s) at the 5-position were synthesized and…”
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Chemistry of Salicylic Acid and Anthranilic Acid. III. Hypoglycemic Screening Tests for Salicylic and Anthranilic Acid Derivatives by ASAKAWA, HIROYUKI, IMAMIYA, EIKO, HAMURO, YUKIHIKO

“…The hypoglycemic activities of O-substituted salicylic acids (1-11), N-substituted anthranilic acids (18-27) and related compounds (12-17, 28-30) were…”
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Studies on antidiabetic agents. II. Synthesis of 5-(4-(1-methylcyclohexylmethoxy)-benzyl)thiazolidine-2,4-dione (ADD-3878) and its derivatives by SOHDA, TAKASHI, MIZUNO, KATSUTOSHI, IMAMIYA, EIKO, SUGIYAMA, YASUO, FUJITA, TAKESHI, KAWAMATSU, YUTAKA

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A facile synthesis of 3-Substituted 5-Oxo-1,2,4-thiadiazoles from amidoximes by Kohara, Yasuhisa, Kubo, Keiji, Imamiya, Eiko, Naka, Takehiko

“…The reaction of amidoximes 1 with 1,1′‐thiocarbonyldiimidazole (TCDI) followed by treatment with silica gel or boron trifluoride diethyl etherate (BF3·OEt2)…”
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Studies on Vitamin B1 and Related Compounds.CVII.Synthesis of Hydroxyethylthiamine Homologs by Oka, Yoshikazu, Imamiya, Eiko, Hirano, Hiroshi

“…Two types of dihydrothiamine derivatives, IV, VI, VIII, and V, VII, IX, were obtained by the reaction of I, II, and phenylglyoxal derivatives. On treatment…”
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Studies on the Synthese of N-Heterocyclic Compounds. III. Hypocholesterolemic 1, 2, 4-Oxadiazole Derivatives (1) by YURUGI, SHOJIRO, MIYAKE, AKIO, FUSHIMI, TOMIYOSHI, IMAMIYA, EIKO, MATSUMURA, HARUKI, IMAI, YOSHIO

“…3, 5-Disubstituted-1, 2, 4-oxadiazole derivatives containing aryl heteryl substituent at 3 position and amino, mercapto, aryl and heteryl substituent at 5…”
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Studies on Antidiabetic Agents. II. Synthesis of 5-[4-(1-Methylcyclohexylmethoxy)-benzyl] thiazolidine-2, 4-dione (ADD-3878) and Its Derivatives by SOHDA, TAKASHI, MIZUNO, KATSUTOSHI, IMAMIYA, EIKO, SUGIYAMA, YASUO, FUJITA, TAKESHI, KAWAMATSU, YUTAKA

“…More than 100 5-substituted thiazolidine-2, 4-diones were prepared and their hypoglycemic and hypolipidemic activities were evaluated with genetically obese…”
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Synthesis and Antitumor Activity of New Amphiphilic Alkylglycerolipids Substituted with a Polar Head Group, 2-(2-Trimethylammonioethoxy)ethyl or a Congeneric Oligo(ethyleneoxy)ethyl Group by UKAWA, Kiyoshi, IMAMIYA, Eiko, YAMAMOTO, HIroaki, AONO, Tetsuya, KOZAI, Yoshio, OKUTANI, Tetsuya, NOMURA, Hiroaki, HONMA, Yoshio, HOZUMI, Motoo, KUDO, Ichiro, INOUE, Keizo

“…A new series of amphiphilic 1-octadecyl glycerolipids (eleven compounds, 1a-k) were designed and synthesized, in which the 3-phosphocholine portion of…”
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Chemistry of Salicylic Acid and Anthranilic Acid. I. Reduction of Methyl Salicylate, Methyl Anthranilate and Their Derivatives with Sodium Borohydride by ASAKAWA, HIROYUKI, FUKUSHIMA, YOSHIYO, IMAMIYA, EIKO, KAWAMATSU, YUTAKA

“…The ester derivatives of salicylic acid and some kinds of anthranilic acid were reduced to corresponding alcohols with sodium borohydride. The reduction…”
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