Search Results - "IMAI, JUN"

Introduction: Challenges of COVID ‐19 pandemic to Japanese society by Imai, Jun

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The first Japanese biobank of patient‐derived pediatric acute lymphoblastic leukemia xenograft models by Tanaka, Kuniaki, Kato, Itaru, Dobashi, Yuu, Imai, Jun‐ichi, Mikami, Takashi, Kubota, Hirohito, Ueno, Hiroo, Ito, Mamoru, Ogawa, Seishi, Nakahata, Tatsutoshi, Takita, Junko, Toyoda, Hidemi, Ogawa, Chitose, Adachi, Souichi, Watanabe, Shinya, Goto, Hiroaki

“…A lack of practical resources in Japan has limited preclinical discovery and testing of therapies for pediatric relapsed and refractory acute lymphoblastic…”
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Comparison of Thermal Characteristics in Various Aspect Ratios for Radial-Flux and Axial-Flux Permanent Magnet Machines by Tsunata, Ren, Takemoto, Masatsugu, Imai, Jun, Saito, Tatsuya, Ueno, Tomoyuki

“…This paper proposes an axial-flux permanent magnet machine (AFPM) that uses a neodymium-bonded permanent magnet (Nd-bonded PM) and a coreless rotor structure…”
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Constitutive activation of nuclear factor‐κB is preferentially involved in the proliferation of basal‐like subtype breast cancer cell lines by Yamaguchi, Noritaka, Ito, Taku, Azuma, Sakura, Ito, Emi, Honma, Reiko, Yanagisawa, Yuka, Nishikawa, Akira, Kawamura, Mika, Imai, Jun‐ichi, Watanabe, Shinya, Semba, Kentaro, Inoue, Jun‐ichiro

“…Constitutive nuclear factor (NF)‐κB activation is thought to be involved in survival, invasion, and metastasis in various types of cancers. However, neither…”
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Tumor mutation burden and immunological, genomic, and clinicopathological factors as biomarkers for checkpoint inhibitor treatment of patients with non-small-cell lung cancer by Ozaki, Yuki, Muto, Satoshi, Takagi, Hironori, Watanabe, Masayuki, Inoue, Takuya, Fukuhara, Mitsuro, Yamaura, Takumi, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Ohsugi, Jun, Hoshino, Mika, Shio, Yutaka, Tanaka, Daisuke, Nanamiya, Hideaki, Imai, Jun-ichi, Isogai, Takao, Watanabe, Shinya, Suzuki, Hiroyuki

“…Cancer treatment using immune checkpoint inhibitors is widely used, although biomarkers predictive of response are not well established. However, both the…”
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Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities by Murasawa, Hiroyasu, Kobayashi, Hiroyuki, Imai, Jun, Nagase, Takahiko, Soumiya, Hitomi, Fukumitsu, Hidefumi

“…Rett syndrome (RTT) is a neurodevelopmental disorder with X-linked dominant inheritance caused mainly by mutations in the methyl-CpG-binding protein 2 ( MECP2…”
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Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities by Hiroyasu Murasawa, Hiroyuki Kobayashi, Jun Imai, Takahiko Nagase, Hitomi Soumiya, Hidefumi Fukumitsu

“…Rett syndrome (RTT) is a neurodevelopmental disorder with X-linked dominant inheritance caused mainly by mutations in the methyl-CpG-binding protein 2 (MECP2)…”
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Doping of Nb5+ Species at the Au–TiO2 Interface for Plasmonic Photocatalysis Enhancement by Shiraishi, Yasuhiro, Imai, Jun, Yasumoto, Naoki, Sakamoto, Hirokatsu, Tanaka, Shunsuke, Ichikawa, Satoshi, Hirai, Takayuki

“…Au nanoparticles loaded on semiconductor TiO2 absorb visible light due to their surface plasmon resonance (SPR) and inject the photogenerated hot electrons…”
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Photocatalytic Dehalogenation of Aromatic Halides on Ta2O5‑Supported Pt–Pd Bimetallic Alloy Nanoparticles Activated by Visible Light by Sakamoto, Hirokatsu, Imai, Jun, Shiraishi, Yasuhiro, Tanaka, Shunsuke, Ichikawa, Satoshi, Hirai, Takayuki

“…Dehalogenation of aromatic halides is one important reaction for detoxification and organic synthesis. Photocatalytic dehalogenation with alcohol, a safe…”
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Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation by Imai, Jun, Otani, Mayu, Sakai, Takahiro

“…Dendritic cells (DCs) present exogenous protein-derived peptides on major histocompatibility complex class I molecules to prime naïve CD8 T cells. This DC…”
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Design and Analysis of Hybrid-Excitation Variable Flux Memory Motor for Traction Applications: Improving Output Power in High-Speed Area During Six-Step Operation Mode by Tsunata, Ren, Yokomichi, Keito, Takemoto, Masatsugu, Imai, Jun

“…Variable flux motors with adjustable magnetic flux have been gaining attention because of their capability to simultaneously achieve a high torque density and…”
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Clinical implication of oncogenic somatic mutations in early-stage cervical cancer with radical hysterectomy by Watanabe, Takafumi, Nanamiya, Hideaki, Kojima, Manabu, Nomura, Shinji, Furukawa, Shigenori, Soeda, Shu, Tanaka, Daisuke, Isogai, Takao, Imai, Jun-ichi, Watanabe, Shinya, Fujimori, Keiya

“…It is well known that tumour initiation and progression are primarily an accumulation of genetic mutations. The mutation status of a tumour may predict…”
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Neonatal bilateral whisker trimming in male mice age-dependently alters brain neurotransmitter levels and causes adolescent onsets of social behavior abnormalities by Murasawa, Hiroyasu, Soumiya, Hitomi, Kobayashi, Hiroyuki, Imai, Jun, Nagase, Takahiko, Fukumitsu, Hidefumi

“…Tactile perception via whiskers is important in rodent behavior. Whisker trimming during the neonatal period affects mouse behaviors related to both…”
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Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues by Tamura, Hirosumi, Higa, Arisa, Hoshi, Hirotaka, Hiyama, Gen, Takahashi, Nobuhiko, Ryufuku, Masae, Morisawa, Gaku, Yanagisawa, Yuka, Ito, Emi, Imai, Jun-Ichi, Dobashi, Yuu, Katahira, Kiyoaki, Soeda, Shu, Watanabe, Takafumi, Fujimori, Keiya, Watanabe, Shinya, Takagi, Motoki

“…Patient-derived tumor xenograft models represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture;…”
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Clinical relevance of oncogenic driver mutations identified in endometrial carcinoma by Watanabe, Takafumi, Nanamiya, Hideaki, Kojima, Manabu, Nomura, Shinji, Furukawa, Shigenori, Soeda, Shu, Tanaka, Daisuke, Isogai, Takao, Imai, Jun-ichi, Watanabe, Shinya, Fujimori, Keiya

“…•Comprehensive somatic mutations profiling in endometrial carcinoma.•Relationships between somatic mutations and clinicopathological…”
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A Proposal of an Axial-Flux Permanent-Magnet Machine Employing SMC Core With Tooth-Tips Constructed by One-Pressing Process: Improving Torque and Manufacturability by Tsunata, Ren, Takemoto, Masatsugu, Imai, Jun, Saito, Tatsuya, Ueno, Tomoyuki

“…This study aims to improve the torque performance and manufacturability of axial-flux permanent magnet (AFPM) machines. Hence, we propose a novel AFPM machine…”
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Autocrine and Paracrine Interactions between Multiple Myeloma Cells and Bone Marrow Stromal Cells by Growth Arrest-specific Gene 6 Cross-talk with Interleukin-6 by Furukawa, Miki, Ohkawara, Hiroshi, Ogawa, Kazuei, Ikeda, Kazuhiko, Ueda, Koki, Shichishima-Nakamura, Akiko, Ito, Emi, Imai, Jun-ichi, Yanagisawa, Yuka, Honma, Reiko, Watanabe, Shinya, Waguri, Satoshi, Ikezoe, Takayuki, Takeishi, Yasuchika

“…The pathogenesis of multiple myeloma (MM) has not yet been fully elucidated. Our microarray analysis and immunohistochemistry revealed significant…”
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Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence by Sakai, Takahiro, Kurokawa, Ryosuke, Hirano, Shin-Ichi, Imai, Jun

“…Bacteria inhabiting the human gut metabolize microbiota-accessible carbohydrates (MAC) contained in plant fibers and subsequently release metabolic products…”
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The novel antioxidant TA293 reveals the role of cytoplasmic hydroxyl radicals in oxidative stress-induced senescence and inflammation by Sakai, Takahiro, Imai, Jun, Ito, Tomohiro, Takagaki, Hidetsugu, Ui, Michio, Hatta, Shinichi

“…The hydroxyl radical (OH) possesses the strongest oxidation potential among reactive oxygen species (ROS). Hydroxyl radicals react nonpreferentially with…”
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Structural Colored Balloons Responsive to pH Change by Higashiguchi, Kenji, Imai, Jun, Matsuda, Kenji

“…Structural colored balloons (SCBs) composed of poly­(4-vinylpyridine-co-styrene) (P4VP-PS) exhibited a pH-controlled structural color change in the presence…”
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