Search Results - "IM, Krishnakumar"

Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study by K, Mamatha, Aryan, Manu Kanjoormana, Prabhakaran, Prathibha, Mulakal, Johannah Natinga, Das S, Syam, Im, Krishnakumar, Parameswara Panicker, Sreejith

“…Allergic rhinitis (AR) is an IgE-mediated reaction to inhaled allergens, and is a prominent health concern affecting approximately 400 million people…”
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An enhanced bioavailable formulation of curcumin using fenugreek-derived soluble dietary fibre by IM, Krishnakumar, Ravi, Abhilash, Kumar, Dinesh, Kuttan, Ramadasan, Maliakel, Balu

“…Poor intestinal absorption has been regarded as a major limiting factor for the therapeutic use of curcumin, the primary active constituent of turmeric…”
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Dietary addition of a standardized extract of turmeric (TurmaFEED TM ) improves growth performance and carcass quality of broilers by Nm, Johannah, Joseph, Ashil, Maliakel, Balu, Im, Krishnakumar

“…Indiscriminate use of antibiotics in livestock and poultry farming has caused emergence of new pathogenic strains. The situation has warrented the development…”
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Exploring the possibility of a proprietary black cumin oil extract as a Dual Orexin Receptor Antagonist in restoring stress-sleep balance on stress-induced sleep deprived animals by OR, Saneha, Krishna, Priya, Das S, Syam, IM, Krishnakumar, Joseph, Litty

“…Orexins act as a molecular switch for the release of cortisol/corticosterone in response to a stress stimulus and hence to regulate sleep/wake cycle. Orexin…”
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Improved blood–brain-barrier permeability and tissue distribution following the oral administration of a food-grade formulation of curcumin with fenugreek fibre by IM, Krishnakumar, Maliakel, Abhilash, G, Gopakumar, Kumar, Dinesh, Maliakel, Balu, Kuttan, Ramadasan

“…•A food grade water soluble formulation of curcumin with fenugreek dietary fibre.•UPLC-ESI-MS/MS studies on rats for oral bioavailability and tissue…”
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Enhanced bioavailability and relative distribution of free (unconjugated) curcuminoids following the oral administration of a food-grade formulation with fenugreek dietary fibre: A randomised double-blind crossover study by Kumar, Dinesh, Jacob, Della, PS, Subash, Maliakkal, Abhilash, NM, Johannah, Kuttan, Ramadassan, Maliakel, Balu, Konda, Veera, IM, Krishnakumar

“…•Enhanced free curcuminoids oral bioavailability (>45×) with improved pharmacokinetics.•Randomised double-blinded crossover study on largest number of subjects…”
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Enhanced absorption and pharmacokinetics of fresh turmeric (Curcuma Longa L) derived curcuminoids in comparison with the standard curcumin from dried rhizomes by Krishnakumar, IM, Kumar, Dinesh, Ninan, Eapen, Kuttan, Ramadassan, Maliakel, Balu

“…•Preparation of curcuminoids from fresh turmeric rhizomes.•Ultrasound-mediated enzymatic expression of curcuminoids-rich juice.•Oral absorption studies on…”
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Safety assessment of a fenugreek dietary fiber-based formulation of capsaicinoids-rich red chili (Capsicum annum) extract (Capsifen®): Acute and sub-chronic studies by Joseph, Ashil, NM, Johannah, Kumar, Suresh, S, Syam Das, Maliakel, Balu, IM, Krishnakumar

“…Despite the promising health beneficial effects (thermogenic, lipolytic, hypotriglyceridemic, hypocholesterolemic, anti-inflammatory and anticancer) of…”
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Safety, Tolerance, and Enhanced Efficacy of a Bioavailable Formulation of Curcumin With Fenugreek Dietary Fiber on Occupational Stress: A Randomized, Double-Blind, Placebo-Controlled Pilot Study by Pandaran Sudheeran, Subash, Jacob, Della, Natinga Mulakal, Johannah, Gopinathan Nair, Gopakumar, Maliakel, Abhilash, Maliakel, Balu, Kuttan, Ramadasan, Im, Krishnakumar

“…Drug delivery systems capable of delivering free (unconjugated) curcuminoids is of great therapeutic significance, since the absorption of bioactive and…”
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Curcumin-Galactomannoside Complex inhibits the Proliferation of Human Cervical Cancer Cells: Possible Role in Cell Cycle Arrest and Apoptosis by M, Ratheesh, Jose, Svenia P, IM, Krishnakumar, S, Sandya, Saji, Sangeeth, S, Sheethal

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A comparison of rigid and flexible crosslinked polymer-supported peptide synthesis by Krishnakumar, I.M., Mathew, Beena

“…To correlate the coupling difficulty and nature of the support in solid-phase peptide synthesis, a set of difficult peptides were built under identical…”
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Surface-engineered liposomal particles of calcium ascorbate with fenugreek galactomannan enhanced the oral bioavailability of ascorbic acid: a randomized, double-blinded, 3-sequence, crossover study by Joseph, Ashil, Kumar, Dinesh, Balakrishnan, Abhilash, Shanmughan, Prasanth, Maliakel, Balu, IM, Krishnakumar

“…The antioxidant, anti-inflammatory, immunomodulating, anti-thrombotic, and antiviral effects along with its protective effects against respiratory infections…”
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Efficacy of a novel extract of fenugreek seeds in alleviating vasomotor symptoms and depression in perimenopausal women: A randomized, double‐blinded, placebo‐controlled study by Khanna, Aman, John, Febi, Das, Syam, Thomas, Jestin, Rao, Jyoti, Maliakel, Balu, IM, Krishnakumar

“…The present randomized, double‐blinded, placebo‐controlled study investigated the effect of a standardized fenugreek extract (FHE) on perimenopausal…”
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Amelioration of Radiation-Induced Damages in Mice by Curcuminoids: The Role of Bioavailability by Liju, Vijayasteltar B., Thomas, Angel, Sivadasan, Syam Das, Kuttan, Ramadasan, Maliakel, Balu, IM, Krishnakumar

“…The present study investigated the role of free curcuminoids bioavailability on the relative radioprotective efficacy of natural unformulated curcuminoids. A…”
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Phytoestrogenic effect of fenugreek seed extract helps in ameliorating the leg pain and vasomotor symptoms in postmenopausal women: A randomized, double-blinded, placebo-controlled study by Thomas, Jestin V., Rao, Jyoti, John, Febi, Begum, Shamshad, Maliakel, Balu, IM, Krishnakumar, Khanna, Aman

“…[Display omitted] Fenugreek is a popular spice which has been evaluated for hormone related disorders. The present randomized, double-blinded,…”
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Thymoquinone-rich black cumin oil improves sleep quality, alleviates anxiety/stress on healthy subjects with sleep disturbances– A pilot polysomnography study by Das S, Syam, R, Kannan, George, Sanju, PS, Baby Chakrapani, Maliakel, Balu, Ittiyavirah, Sibi, IM, Krishnakumar

“…Insomnia, the inability to get sleep or sleep well at night, is a universal health problem. In the present single-arm, open-label, pilot study, the safety and…”
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A novel powder formulation of coconut inflorescence sap inhibits alcoholic liver damage by modulating inflammatory markers, extracellular matrix metalloproteinase, and oxidative stress by Jose, Svenia P., Mohanan, Ratheesh, S, Sandya, S, Asha, IM, Krishnakumar

“…Despite the fact that unfermented coconut inflorescence sap (CSP) is a popular health drink in many of the Asian countries, systematic investigations on its…”
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Nephro-protective effect of a novel formulation of unopened coconut inflorescence sap powder on gentamicin induced renal damage by modulating oxidative stress and inflammatory markers by Jose, Svenia P, S, Asha, IM, Krishnakumar, M, Ratheesh, Santhosh, Savitha, S, Sandya, B, Girish Kumar, C, Pramod

“…Abstract Fresh oyster white translucent sap obtained from the tender unopened inflorescence of coconut trees ( Cocos nucifera ) is identified to have great…”
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Polyethyleneglycol graft copoly (styrene-1,4-butanediol dimethacrylate) resin for gel-phase peptide synthesis by Krishnakumar, I. M., Mathew, Beena

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Effects of the polyphenol content on the anti-diabetic activity of Cinnamomum zeylanicum extracts by IM, Krishnakumar, Issac, Abin, NM, Johannah, Ninan, Eapen, Maliakel, Balu, Kuttan, Ramadassan

“…Cinnamomum zeylanicum is a popular kitchen spice widely investigated for insulin potentiating effects. Though a group of water soluble polyphenols belonging to…”
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