Search Results - "ILONEN, J"

Genetic susceptibility to type 1 diabetes in childhood - estimation of HLA class II associated disease risk and class II effect in various phases of islet autoimmunity by Ilonen, J, Kiviniemi, M, Lempainen, J, Simell, O, Toppari, J, Veijola, R, Knip, M

“…Objective The HLA‐DR/DQ region remains the major determinant of susceptibility to type 1 diabetes (T1D) despite the more than 50 risk affecting loci outside…”
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Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1 by Vuorela, A., Freitag, T. L., Leskinen, K., Pessa, H., Härkönen, T., Stracenski, I., Kirjavainen, T., Olsen, P., Saarenpää-Heikkilä, O., Ilonen, J., Knip, M., Vaheri, A., Partinen, M., Saavalainen, P., Meri, S., Vaarala, O.

“…Narcolepsy type 1 (NT1) is a chronic neurological disorder having a strong association with HLA-DQB1*0602, thereby suggesting an immunological origin…”
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Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk by Parikka, V., Näntö-Salonen, K., Saarinen, M., Simell, T., Ilonen, J., Hyöty, H., Veijola, R., Knip, M., Simell, O.

“…Aims/hypothesis The aim of the study was to investigate the timing of the appearance of autoantibodies associated with type 1 diabetes between birth and…”
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Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children by Erkkola, M., Kaila, M., Nwaru, B. I., Kronberg-Kippilä, C., Ahonen, S., Nevalainen, J., Veijola, R., Pekkanen, J., Ilonen, J., Simell, O., Knip, M., Virtanen, S. M.

“…Summary Background Vitamin D is known to have a number of immunological effects and it may play a role in preventing allergic diseases. Objectives To study the…”
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Gliptin-associated Bullous Pemphigoid and the Expression of Dipeptidyl Peptidase-4/CD26 in Bullous Pemphigoid by Lindgren, Outi, Varpuluoma, Outi, Tuusa, Jussi, Ilonen, Jorma, Huilaja, Laura, Kokkonen, Nina, Tasanen, Kaisa

“…Dipeptidyl peptidase-4 inhibitors (DPP-4i or gliptins) increase the risk of developing bullous pemphigoid (BP). To clarify, whether gliptin-associated BP has…”
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Early childhood infections precede development of beta‐cell autoimmunity and type 1 diabetes in children with HLA‐conferred disease risk by Mustonen, N, Siljander, H, Peet, A, Tillmann, V, Härkönen, T, Ilonen, J, Hyöty, H, Knip, M

“…Background The etiology of type 1 diabetes (T1D) is largely unknown. Infections and microbial exposures are believed to play a role in the pathogenesis and in…”
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Circulating β cell‐specific CD8+ T cells restricted by high‐risk HLA class I molecules show antigen experience in children with and at risk of type 1 diabetes by Yeo, L., Pujol‐Autonell, I., Baptista, R., Eichmann, M., Kronenberg‐Versteeg, D., Heck, S., Dolton, G., Sewell, A. K., Härkönen, T., Mikk, M.‐L., Toppari, J., Veijola, R., Knip, M., Ilonen, J., Peakman, M.

“…Summary In type 1 diabetes (T1D), autoreactive cytotoxic CD8+ T cells are implicated in the destruction of insulin‐producing β cells. The HLA‐B*3906 and…”
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Maternal intake of vitamin D during pregnancy and risk of advanced beta cell autoimmunity and type 1 diabetes in offspring by Marjamäki, L, Niinistö, S, Kenward, M. G, Uusitalo, L, Uusitalo, U, Ovaskainen, M.-L, Kronberg-Kippilä, C, Simell, O, Veijola, R, Ilonen, J, Knip, M, Virtanen, S. M

“…Aims/hypothesis We evaluated the intake of vitamin D by pregnant Finnish women and examined associations between maternal intake of vitamin D and the…”
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Maternal diet during pregnancy and lactation and cow’s milk allergy in offspring by Tuokkola, J, Luukkainen, P, Tapanainen, H, Kaila, M, Vaarala, O, Kenward, M G, Virta, L J, Veijola, R, Simell, O, Ilonen, J, Knip, M, Virtanen, S M

“…Background/Objectives: Diet during pregnancy and lactation may have a role in the development of allergic diseases. There are few human studies on the topic,…”
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Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort by Nwaru, B. I., Takkinen, H.‐M., Niemelä, O., Kaila, M., Erkkola, M., Ahonen, S., Tuomi, H., Haapala, A.‐M., Kenward, M. G., Pekkanen, J., Lahesmaa, R., Kere, J., Simell, O., Veijola, R., Ilonen, J., Hyöty, H., Knip, M., Virtanen, S. M.

“…Objective To study the associations between timing and diversity of introduction of complementary foods during infancy and atopic sensitization in 5‐year‐old…”
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Autoantibodies against zinc transporter 8 are related to age, metabolic state and HLA DR genotype in children with newly diagnosed type 1 diabetes by Salonen, K. M., Ryhänen, S., Härkönen, T., Ilonen, J., Knip, M.

“…Background We set out to define the characteristics of humoral autoimmunity against ZnT8 in children and adolescents with newly diagnosed T1D in relation to…”
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Interaction of enterovirus infection and cow's milk-based formula nutrition in type 1 diabetes-associated autoimmunity by Lempainen, J., Tauriainen, S., Vaarala, O., Mäkelä, M., Honkanen, H., Marttila, J., Veijola, R., Simell, O, Hyöty, H., Knip, M., Ilonen, J.

“…Background Enteral virus infections and early introduction of cow's milk (CM)‐based formula are among the suggested triggers of type 1 diabetes…”
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Serum carotenoid and tocopherol concentrations and risk of asthma in childhood: a nested case–control study by Hämäläinen, N., Nwaru, B. I., Erlund, I., Takkinen, H.‐M., Ahonen, S., Toppari, J., Ilonen, J., Veijola, R., Knip, M., Kaila, M., Virtanen, S. M.

“…Summary Background The antioxidant hypothesis regarding the risk of asthma in childhood has resulted in inconsistent findings. Some data indicate that the role…”
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Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study: recruitment, intervention and follow-up by Akerblom, H K, Krischer, J, Virtanen, S M, Berseth, C, Becker, D, Dupré, J, Ilonen, J, Trucco, M, Savilahti, E, Koski, K, Pajakkala, E, Fransiscus, M, Lough, G, Bradley, B, Koski, M, Knip, M

“…Aims/hypothesis The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study was designed to establish whether weaning to a highly hydrolysed formula in…”
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Intake of antioxidants during pregnancy and the risk of allergies and asthma in the offspring by Nwaru, B I, Erkkola, M, Ahonen, S, Kaila, M, Kronberg-Kippilä, C, Ilonen, J, Simell, O, Knip, M, Veijola, R, Virtanen, S M

“…Background/Objectives: The potential immune functions related to the damages induced by oxygen-free radicals suggest that antioxidants may have a role in the…”
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Maternal fatty acid intake during pregnancy and the development of childhood overweight: a birth cohort study by Hakola, L., Takkinen, H‐M., Niinistö, S., Ahonen, S., Erlund, I., Rautanen, J., Veijola, R., Ilonen, J., Toppari, J., Knip, M., Virtanen, S. M., Lehtinen‐Jacks, S.

“…Summary Background Maternal diet during pregnancy may contribute to the risk of offspring adiposity. Objectives The objective of the study is to explore the…”
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Analysis of pancreas tissue in a child positive for islet cell antibodies by Oikarinen, M, Tauriainen, S, Honkanen, T, Vuori, K, Karhunen, P, Vasama-Nolvi, C, Oikarinen, S, Verbeke, C, Blair, G. E, Rantala, I, Ilonen, J, Simell, O, Knip, M, Hyöty, H

“…Aims/hypothesis Type 1 diabetes is caused by an immune-mediated process, reflected by the appearance of autoantibodies against pancreatic islets in the…”
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Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki, Finland by Oilinki, T, Otonkoski, T, Ilonen, J, Knip, M, Miettinen, PJ

“…Oilinki T, Otonkoski T, Ilonen J, Knip M, Miettinen PJ. Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki,…”
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The association of the HLA‐A24:02, B39:01 and B39:06 alleles with type 1 diabetes is restricted to specific HLA‐DR/DQ haplotypes in Finns by Mikk, M.‐L., Heikkinen, T., El‐Amir, M. I., Kiviniemi, M., Laine, A.‐P., Härkönen, T., Veijola, R., Toppari, J., Knip, M., Ilonen, J.

“…Background We analysed the previously reported association of the HLA‐A*24:02, B*18 and B*39 alleles with type 1 diabetes and diabetes associated autoimmunity…”
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Age at introduction of new foods and advanced beta cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes by VIRTANEN, S. M, KENWARD, M. G, SIMELL, O, ILONEN, J, KNIP, M, ERKKOLA, M, KAUTIAINEN, S, KRONBERG-KIPPILA, C, HAKULINEN, T, AHONEN, S, UUSITALO, L, NIINISTÖ, S, VEIJOLA, R

“…Evidence for the role of infant feeding in the development of beta cell autoimmunity is inconsistent. We set out to study the effects of breastfeeding and of…”
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