Search Results - "IKEMATSU, HIDEYUKI"

Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts by Ikematsu, Hideyuki, Hayden, Frederick G, Kawaguchi, Keiko, Kinoshita, Masahiro, de Jong, Menno D, Lee, Nelson, Takashima, Satoru, Noshi, Takeshi, Tsuchiya, Kenji, Uehara, Takeki

“…In a randomized, double-blind trial that treated household contacts of patients with influenza with a single dose of baloxavir or placebo, participants taking…”
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Effect of seasonal vaccination on the selection of influenza A/H3N2 epidemic variants by Chong, Yong, Ikematsu, Hideyuki

“…Highlights • The effect of vaccination on the dynamics of influenza viruses remains unknown in humans. • Our study showed higher mutations within epitopes in…”
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Laninamivir octanoate: a new long-acting neuraminidase inhibitor for the treatment of influenza by Ikematsu, Hideyuki, Kawai, Naoki

“…Oseltamivir and zanamivir are well-established and well-researched drugs for the treatment of influenza in Japan and the rest of the world. A new neuraminidase…”
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High genetic stability in MDCK-SIAT1 passaged human influenza viruses by Matsumoto, Shinya, Chong, Yong, Kang, Dongchon, Ikematsu, Hideyuki

“…MDCK-induced amino acid (AA) mutation, such as D151G/N in the neuraminidase (NA) of influenza A/H3N2 viruses, is of concern. MDCK-SIAT1 cells, modified…”
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Is seasonal vaccination a contributing factor to the selection of influenza epidemic variants? by Chong, Yong, Ikematsu, Hideyuki

“…Influenza A/H3N2 viruses are the most common and virulent subtypes for humans. Antigenic drift, changes in antigenicity through the accumulation of mutations…”
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Consecutive influenza surveillance of neuraminidase mutations and neuraminidase inhibitor resistance in Japan by Chong, Yong, Matsumoto, Shinya, Kang, Dongchon, Ikematsu, Hideyuki

“…Background The large consumption of neuraminidase inhibitors (NAIs) for the treatment of influenza virus infections places Japan at risk of becoming the…”
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Spread of predominant neuraminidase and hemagglutinin co-mutations in the influenza A/H3N2 virus genome by Chong, Yong, Ikematsu, Hideyuki

“…Genetic variation of influenza neuraminidase (NA), unlike for hemagglutinin (HA), has not been fully characterized. Therefore, we determined the relation…”
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Post-vaccination antibody evaluation for nosocomial SARS-CoV-2 delta variant breakthrough infection by Goto, Takeyuki, Tani, Naoki, Ikematsu, Hideyuki, Gondo, Kei, Oishi, Ryo, Minami, Junya, Onozawa, Kyoko, Kuwano, Hiroyuki, Akashi, Koichi, Shimono, Nobuyuki, Chong, Yong

“…Waning humoral immunity after mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a significant problem for public health…”
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Correlation of patient symptoms with SARS-CoV-2 Omicron variant viral loads in nasopharyngeal and saliva samples and their influence on the performance of rapid antigen testing by Shiraishi, Kenichiro, Chong, Yong, Goto, Takeyuki, Ishimaru, Toshiyuki, Shimono, Nobuyuki, Ikematsu, Hideyuki, Akashi, Koichi

“…Evaluating SARS-CoV-2 viral loads in nasopharyngeal (NP) and saliva samples, factors affecting viral loads, and the performance of rapid antigen testing (RAT)…”
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Post-vaccination antibody evaluation for nosocomial SARS-CoV-2 delta variant breakthrough infection by Takeyuki Goto, Naoki Tani, Hideyuki Ikematsu, Kei Gondo, Ryo Oishi, Junya Minami, Kyoko Onozawa, Hiroyuki Kuwano, Koichi Akashi, Nobuyuki Shimono, Yong Chong

“…Waning humoral immunity after mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a significant problem for public health…”
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A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza by Nabeshima, Shigeki, Kashiwagi, Kenichiro, Ajisaka, Kazuhiko, Masui, Shinta, Takeoka, Hiroaki, Ikematsu, Hideyuki, Kashiwagi, Seizaburo

“…Abstract The herbal medicine, maoto, has been traditionally prescribed to patients with influenza in Japan. To better understand the efficacy of maoto for the…”
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Genetic testing and serological screening for SARS-CoV-2 infection in a COVID-19 outbreak in a nursing facility in Japan by Chong, Yong, Tani, Naoki, Ikematsu, Hideyuki, Terazawa, Nobuto, Nakashima, Hitoshi, Shimono, Nobuyuki, Akashi, Koichi, Tanaka, Yosuke

“…The Pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has critically impacted the spread of…”
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In vitro neuraminidase inhibitory concentration (IC50) of four neuraminidase inhibitors in the Japanese 2018–19 season: Comparison with the 2010–11 to 2017–18 seasons by Ikematsu, Hideyuki, Kawai, Naoki, Tani, Naoki, Chong, Yong, Bando, Takuma, Iwaki, Norio, Kashiwagi, Seizaburo

“…To assess the extent of susceptibility to the four most commonly used neuraminidase inhibitors (NAIs) of the epidemic viruses in the 2018-19 Japanese influenza…”
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Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate for influenza treatment; comparison among the four Japanese influenza seasons from 2011-2012 to 2014-2015 by Ikematsu, Hideyuki, MD, Kawai, Naoki, Iwaki, Norio, Kashiwagi, Seizaburo

“…Abstract The duration of fever and other symptoms as markers of the clinical effectiveness of laninamivir octanoate hydrate (laninamivir) were investigated in…”
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Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate: A study of the 2017/18 and 2018/19 seasons and comparison with the 2011/12 to 2016/17 Japanese influenza seasons by Tani, Naoki, Kawai, Naoki, Ikematsu, Hideyuki, Bando, Takuma, Iwaki, Norio, Takasaki, Yoshio, Shindo, Shizuo, Chong, Yong, Kashiwagi, Seizaburo

“…Large scale investigation of the clinical effectiveness of neuraminidase inhibitors for circulating influenza viruses are important along with the surveillance…”
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In vitro neuraminidase inhibitory activities of four neuraminidase inhibitors against influenza viruses isolated in the 2010–2011 season in Japan by Ikematsu, Hideyuki, Kawai, Naoki, Kashiwagi, Seizaburo

“…Abstract The half maximal inhibitory concentration (IC50 ) of four neuraminidase inhibitors (NAIs), oseltamivir, zanamivir, laninamivir, and peramivir; was…”
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In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against clinical isolates of the influenza virus circulating in the Japanese 2013–2014 season by Ikematsu, Hideyuki, Kawai, Naoki, Iwaki, Norio, Kashiwagi, Seizabro

“…Abstract To assess the extent of viral resistance, we measured the 50% inhibitory concentration (IC50 ) of neuraminidase inhibitors (NAIs) for the influenza…”
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Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate; comparison of the 2011/12 to 2015/16 Japanese influenza seasons by Ikematsu, Hideyuki, Kawai, Naoki, Iwaki, Norio, Kashiwagi, Seizaburo

“…The duration of fever and symptoms after laninamivir octanoate hydrate (laninamivir) inhalation were investigated in the Japanese 2015/16 influenza season, and…”
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In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against clinical isolates of influenza virus in the Japanese 2012–2013 season by Ikematsu, Hideyuki, Kawai, Naoki, Iwaki, Norio, Kashiwagi, Seizaburo

“…Abstract The neuraminidase inhibitors (NAIs) oseltamivir phosphate (Tamiflu® ), zanamivir (Relenza® ), laninamivir octanoate (Inavir® ), and peramivir…”
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In vitro neuraminidase inhibitory concentration (IC50) of four neuraminidase inhibitors in the Japanese 2017–18 season: Comparison with the 2010–11 to 2016–17 seasons by Ikematsu, Hideyuki, Kawai, Naoki, Chong, Yong, Bando, Takuma, Iwaki, Norio, Kashiwagi, Seizaburo

“…To assess the extent of susceptibility to the four most commonly used neuraminidase inhibitors (NAIs) of the viruses epidemic in the 2017-18 Japanese influenza…”
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