Search Results - "IKEGAMI, Tohru"
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Hydrophilic interaction chromatography for the analysis of biopharmaceutical drugs and therapeutic peptides: A review based on the separation characteristics of the hydrophilic interaction chromatography phases
Published in Journal of separation science (01-01-2019)“…Applications of hydrophilic interaction chromatography for the analysis of biopharmaceutical drugs, i.e., glycosylated proteins represented by monoclonal…”
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2
Separation efficiencies in hydrophilic interaction chromatography
Published in Journal of Chromatography A (14-03-2008)“…Hydrophilic interaction chromatography (HILIC) is important for the separation of highly polar substances including biologically active compounds, such as…”
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3
The relationship between polymer structures on silica particles and the separation characteristics of the corresponding columns for hydrophilic interaction chromatography
Published in Journal of Chromatography A (10-05-2020)“…•20 Poly(acrylamide) type columns were synthesized by surface-initiated ATRP.•The new HILIC columns were characterized chromatographically.•Density of polymer…”
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Separation of carbohydrate isomers and anomers on poly-N-(1H-tetrazole-5-yl)-methacrylamide-bonded stationary phase by hydrophilic interaction chromatography as well as determination of anomer interconversion energy barriers
Published in Journal of Chromatography A (07-06-2020)“…•DCpak PTZ HILIC column was evaluated for neutral carbohydrate separations.•Anomer and isomer separations of pentoses, hexoses and disaccharides.•Rate…”
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5
Chromatographic characterization of hydrophilic interaction liquid chromatography stationary phases: Hydrophilicity, charge effects, structural selectivity, and separation efficiency
Published in Journal of Chromatography A (02-09-2011)“…Fourteen commercially available particle-packed columns and a monolithic column for hydrophilic interaction liquid chromatography (HILIC) were characterized in…”
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Recent Progress in Monolithic Silica Columns for High-Speed and High-Selectivity Separations
Published in Annual review of analytical chemistry (Palo Alto, Calif.) (12-06-2016)“…Monolithic silica columns have greater (through-pore size) (skeleton size) ratios than particulate columns and fixed support structures in a column for…”
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Retention characteristics of poly(N-(1H-tetrazole-5-yl)-methacrylamide)-bonded stationary phase in hydrophilic interaction chromatography
Published in Journal of Chromatography A (04-01-2020)“…•Poly(N-(1H-tetrazole-5-yl)-methacrylamide)-bonded silica is effective for HILIC.•HILIC performance is pH dependent due acidic tetrazolyl moiety.•Increase in…”
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8
Method optimization of hydrophilic interaction chromatography separation of nucleotides using design of experiment approaches I: Comparison of several zwitterionic columns
Published in Journal of pharmaceutical and biomedical analysis (05-09-2018)“…•A systematic HILIC method for the separation of nucleotides was developed using design of experiment (DOE) approaches.•Optimized HPLC conditions were…”
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Recent advances in silica‐based monoliths: Preparations, characterizations and applications
Published in Journal of separation science (01-08-2011)“…This mini‐review describes recent progress (2009–2010) in the field of silica‐based monolith with special emphasis on the preparation, characterization and…”
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Hydrophilic Interaction Chromatography Using a Meter-Scale Monolithic Silica Capillary Column for Proteomics LC-MS
Published in Analytical chemistry (Washington) (15-04-2014)“…A meter-scale monolithic silica capillary column modified with urea-functional groups for hydrophilic interaction liquid chromatography (HILIC) was developed…”
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The performance of hybrid monolithic silica capillary columns prepared by changing feed ratios of tetramethoxysilane and methyltrimethoxysilane
Published in Journal of Chromatography A (2010)“…The effect of a feed ratio of methyltrimethoxysilane (MTMS) to tetramethoxysilane (TMOS) was studied to improve the performance of a hybrid monolithic silica…”
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12
Calculating Optimal Modulation Periods to Maximize the Peak Capacity in Two-Dimensional HPLC
Published in Analytical chemistry (Washington) (15-05-2007)“…Theoretical calculations are presented to optimize modulation period for maximum total peak capacity in comprehensive two-dimensional HPLC (2D-HPLC) taking…”
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13
Highly efficient analysis of underivatized carbohydrates using monolithic-silica-based capillary hydrophilic interaction (HILIC) HPLC
Published in Analytical and bioanalytical chemistry (01-08-2008)“…A polyacrylamide (PAAm)-modified monolithic silica capillary column of increased phase ratio, 200T-PAAm, for hydrophilic interaction liquid chromatography…”
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14
High-Efficiency Liquid Chromatographic Separation Utilizing Long Monolithic Silica Capillary Columns
Published in Analytical chemistry (Washington) (15-11-2008)“…Long monolithic silica-C18 capillary columns of 100 μm i.d. were prepared, and the efficiency was examined using reversed-phase HPLC under a pressure of up to…”
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15
Monolithic silica columns for high-efficiency chromatographic separations
Published in Journal of Chromatography A (02-08-2002)“…Studies on the structural and chromatographic properties of monolithic silica columns were reviewed. Monolithic silica columns prepared from tetraalkoxysilane…”
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Book Review Conference Proceeding Journal Article -
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Estimation and optimization of the peak capacity of one-dimensional gradient high performance liquid chromatography using a long monolithic silica capillary column
Published in Journal of Chromatography A (09-03-2012)“…An estimation of the performance and optimization of gradient HPLC conditions using various columns for maximum total peak capacity was studied for “one-shot…”
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Rapid-Flow and Spin-Trapping ESR Study on Carbonyl-Conjugated Radicals of Modified Poly(vinyl alcohol) Bearing 1,2-Propanediol Pendant Moiety as Intermediates of Graft Copolymerization
Published in Bulletin of the Chemical Society of Japan (2017)“…Based on the results of rapid-flow electron spin resonance (RF-ESR) and spin-trapping (ST-ESR) measurements, carbonyl-conjugated radicals derived from the…”
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Preparation of high efficiency and highly retentive monolithic silica capillary columns for reversed-phase chromatography by chemical modification by polymerization of octadecyl methacrylate
Published in Journal of Chromatography A (13-07-2007)“…High efficiency and highly retentive monolithic silica capillary columns were obtained by polymerization of octadecyl methacrylate using…”
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Journal Article Conference Proceeding -
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Monolithic silica rod columns for high-efficiency reversed-phase liquid chromatography
Published in Journal of Chromatography A (15-04-2011)“…Chromatographic properties of a new type of monolithic silica rod columns were examined. Silica rod columns employed for the study were prepared from…”
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Journal Article Conference Proceeding -
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Blockage of spontaneous Ca2+ oscillation causes cell death in intraerythrocitic Plasmodium falciparum
Published in PloS one (06-07-2012)“…Malaria remains one of the world's most important infectious diseases and is responsible for enormous mortality and morbidity. Resistance to antimalarial drugs…”
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