Search Results - "IKEDA, Shuntaro"

Current status of genome‐wide epigenetic profiling of mammalian preimplantation embryos by Ikeda, Shuntaro

“…Background Genome‐wide information on epigenetic modifications in mammalian preimplantation embryos was an unexplored sanctuary of valuable research insights…”
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Comparative analysis of histone H3K4me3 modifications between blastocysts and somatic tissues in cattle by Ishibashi, Mao, Ikeda, Shuntaro, Minami, Naojiro

“…Epigenetic changes induced in the early developmental stages by the surrounding environment can have not only short-term but also long-term consequences…”
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On-Site Computed Tomography-Derived Fractional Flow Reserve Using a Machine-Learning Algorithm　― Clinical Effectiveness in a Retrospective Multicenter Cohort by Kurata, Akira, Fukuyama, Naoki, Hirai, Kuniaki, Kawaguchi, Naoto, Tanabe, Yuki, Okayama, Hideki, Shigemi, Susumu, Watanabe, Kouki, Uetani, Teruyoshi, Ikeda, Shuntaro, Inaba, Shinji, Kido, Teruhito, Itoh, Toshihide, Mochizuki, Teruhito

“…Background:This study evaluated the diagnostic capability of on-site coronary computed tomography-derived computational fractional flow reserve (CT-FFR)…”
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Comparative analysis of histone H3K27me3 modifications between blastocysts and somatic tissues in cattle by Yamazaki, Satomi, Ikeda, Shuntaro, Minami, Naojiro

“…Epigenetic modifications established in the early developmental stages can have long‐term consequences throughout life. This concept encompasses the…”
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Two autopsy cases of wild-type transthyretin cardiac amyloidosis who died 10 days after technetium-99m-pyrophosphate scintigraphy by Takahashi, Koji, Morioka, Hiroe, Sasaki, Daisuke, Yamamura, Nobuhisa, Kitazawa, Sohei, Ueda, Mitsuharu, Sakaue, Tomoki, Enomoto, Daijiro, Uemura, Shigeki, Okura, Takafumi, Ikeda, Shuntaro

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Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development by Aizawa, Ryutaro, Ibayashi, Megumi, Tatsumi, Takayuki, Yamamoto, Atsushi, Kokubo, Toshiaki, Miyasaka, Naoyuki, Sato, Ken, Ikeda, Shuntaro, Minami, Naojiro, Tsukamoto, Satoshi

“…ABSTRACT Lipid droplets (LDs), which are ubiquitous organelles consisting of a neutral lipid core coated with a phospholipid monolayer, play key roles in the…”
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O-ring-induced transverse aortic constriction (OTAC) is a new simple method to develop cardiac hypertrophy and heart failure in mice by Nakao, Yasuhisa, Aono, Jun, Hamaguchi, Mika, Takahashi, Kayo, Sakaue, Tomohisa, Inoue, Katsuji, Ikeda, Shuntaro, Yamaguchi, Osamu

“…Suture-based transverse aortic constriction (TAC) in mice is one of the most frequently used experimental models for cardiac pressure overload-induced heart…”
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A more accurate analysis of maternal effect genes by siRNA electroporation into mouse oocytes by YAMAMOTO, Takuto, HONDA, Shinnosuke, IDEGUCHI, Issei, SUEMATSU, Motoki, IKEDA, Shuntaro, MINAMI, Naojiro

“…Maternal RNA and proteins accumulate in mouse oocytes and regulate initial developmental stages. Sperm DNA combines with protamine, which is exchanged after…”
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Midkine and cytoplasmic maturation of mammalian oocytes in the context of ovarian follicle physiology by Ikeda, Shuntaro, Yamada, Masayasu

“…Midkine (MK) was originally characterized as a member of a distinct family of neurotrophic factors functioning in the CNS. However, it was later discovered…”
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Intravascular Ultrasound-Derived Virtual Fractional Flow Reserve for the Assessment of Myocardial Ischemia by Seike, Fumiyasu, Uetani, Teruyoshi, Nishimura, Kazuhisa, Kawakami, Hiroshi, Higashi, Haruhiko, Fujii, Akira, Aono, Jun, Nagai, Takayuki, Inoue, Katsuji, Suzuki, Jun, Inaba, Shinji, Okura, Takafumi, Yasuda, Kazunori, Higaki, Jitsuo, Ikeda, Shuntaro

“…Background:Fractional flow reserve (FFR) is widely used for the assessment of myocardial ischemia. Intravascular ultrasound (IVUS) is an intracoronary imaging…”
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Huge Right Coronary Artery Aneurysm in Mixed Connective Tissue Disease by Higashi, Haruhiko, Iio, Chiharuko, Ikeda, Shuntaro, Uetani, Teruyoshi, Inaba, Shinji, Inoue, Katsuji, Sakaue, Tomohisa, Izutani, Hironori, Yamaguchi, Osamu

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ECPELLA-Induced False Ventricular Contraction During Ventricular Fibrillation by Miyazaki, Shigehiro, Higashi, Haruhiko, Takasaki, Yasushi, Miyoshi, Toru, Nishimura, Kazuhisa, Inoue, Katsuji, Ikeda, Shuntaro, Yamaguchi, Osamu

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H4K20 monomethylation inhibition causes loss of genomic integrity in mouse preimplantation embryos by SHIKATA, Daiki, YAMAMOTO, Takuto, HONDA, Shinnosuke, IKEDA, Shuntaro, MINAMI, Naojiro

“…Maintaining genomic integrity in mammalian early embryos, which are deficient in DNA damage repair, is critical for normal preimplantation and subsequent…”
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An Increase in the Ratio of Brain Natriuretic Peptide to Peak Transvalvular Pressure Gradient Suggests Coexistence of Cardiovascular Complications in Elderly Aortic Stenosis Patients by Hamada, Mareomi, Ogimoto, Akiyoshi, Otani, Takashi, Kubota, Norio, Hiasa, Go, Ikeda, Shuntaro

“…The aim of this study was to differentiate between elderly aortic stenosis (AS) patients with and without cardiovascular complications (CCs).In total, 156…”
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Cost-Effectiveness of long-term tolvaptan administration for chronic heart failure treatment in Japan by Nakao, Yasuhisa, Kawakami, Hiroshi, Saito, Makoto, Inoue, Katsuji, Ikeda, Shuntaro, Yamaguchi, Osamu

“…•Long-term tolvaptan (TLV) administration provided no clear benefit for all patients with chronic heart failure.•The TLV strategy may be a cost-effective…”
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Lipofection of siRNA into bovine 8-16-cell stage embryos using zona removal and the well-of-the-well culture system by IKEDA, Shuntaro, SUGIMOTO, Miki, KUME, Shinichi

“…Bovine preimplantation embryos exhibit dramatic biological changes between before and after the 8-16-cell stage. Here we report a simple lipofection method to…”
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Perivascular Adipose Tissue Angiotensin II Type 1 Receptor Promotes Vascular Inflammation and Aneurysm Formation by Sakaue, Tomoki, Suzuki, Jun, Hamaguchi, Mika, Suehiro, Chika, Tanino, Akiko, Nagao, Tomoaki, Uetani, Teruyoshi, Aono, Jun, Nakaoka, Hirotomo, Kurata, Mie, Sakaue, Tomohisa, Okura, Takafumi, Yasugi, Takumi, Izutani, Hironori, Higaki, Jitsuo, Ikeda, Shuntaro

“…Perivascular adipose tissue exhibits characteristics of active local inflammation, which contributes to the development of atherosclerotic disease as a…”
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Elevated Cardiac Enzymes in Hypertrophic Cardiomyopathy Patients With Heart Failure　– A 20-Year Prospective Follow-up Study by Hamada, Mareomi, Shigematsu, Yuji, Ohtani, Takashi, Ikeda, Shuntaro

“…Background:To better understand the evolution of typical hypertrophic cardiomyopathy (HCM) to heart failure (HF), we investigated the relationship between…”
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Deletion of interleukin-18 attenuates abdominal aortic aneurysm formation by Suehiro, Chika, Suzuki, Jun, Hamaguchi, Mika, Takahashi, Kayo, Nagao, Tomoaki, Sakaue, Tomoki, Uetani, Teruyoshi, Aono, Jun, Ikeda, Shuntaro, Okura, Takafumi, Okamura, Haruki, Yamaguchi, Osamu

“…Abdominal aortic aneurysm (AAA) is a common disease; however, its exact pathogenesis remains unknown, and no specific medical therapies are available…”
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Recognition of early stage thigmotaxis in Morris water maze test with convolutional neural network by Higaki, Akinori, Mogi, Masaki, Iwanami, Jun, Min, Li-Juan, Bai, Hui-Yu, Shan, Bao-Shuai, Kan-No, Harumi, Ikeda, Shuntaro, Higaki, Jitsuo, Horiuchi, Masatsugu

“…The Morris water maze test (MWM) is a useful tool to evaluate rodents' spatial learning and memory, but the outcome is susceptible to various experimental…”
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