Search Results - "IJzermans, Jan NM"
-
1
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma
Published in eLife (30-07-2021)“…The molecular events that drive hepatitis B virus (HBV)-mediated transformation and tumorigenesis have remained largely unclear, due to the absence of a…”
Get full text
Journal Article -
2
Perihilar Cholangiocarcinoma: Number of Nodes Examined and Optimal Lymph Node Prognostic Scheme
Published in Journal of the American College of Surgeons (01-05-2016)“…Abstract Background The role of routine lymphadenectomy for perihilar cholangiocarcinoma (PHCC) is still controversial and no study has defined the minimum…”
Get full text
Journal Article -
3
Cholangiocarcinoma landscape in Europe: Diagnostic, prognostic and therapeutic insights from the ENSCCA Registry
Published in Journal of hepatology (01-05-2022)“…Cholangiocarcinoma (CCA) is a rare and heterogeneous biliary cancer, whose incidence and related mortality is increasing. This study investigates the clinical…”
Get full text
Journal Article -
4
Intrahepatic cholangiocarcinoma: current perspectives
Published in OncoTargets and therapy (01-01-2017)“…Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy arising from the liver. ICC makes up about 10% of all cholangiocarcinomas. It arises…”
Get full text
Journal Article -
5
The effect of preoperative chemotherapy treatment in surgically treated intrahepatic cholangiocarcinoma patients—A multi‐institutional analysis
Published in Journal of surgical oncology (01-03-2017)“…INTRODUCTION While preoperative chemotherapy (pCT) is utilized in many intra‐abdominal cancers, the use of pCT among patients with intrahepatic…”
Get full text
Journal Article -
6
Low skeletal muscle mass as a risk factor for postoperative delirium in elderly patients undergoing colorectal cancer surgery
Published in Clinical interventions in aging (01-01-2018)“…Both low skeletal muscle mass (LSMM) and delirium are frequently seen in elderly patients. This study aimed to investigate the association between preoperative…”
Get full text
Journal Article -
7
Laparoscopic versus open peritoneal dialysis catheter insertion, the LOCI-trial: a study protocol
Published in BMC surgery (20-12-2011)“…Peritoneal dialysis (PD) is an effective treatment for end-stage renal disease. It allows patients more freedom to perform daily activities compared to…”
Get full text
Journal Article -
8
Impact of waiting time on post-transplant survival for recipients with hepatocellular carcinoma: A natural experiment randomized by blood group
Published in JHEP reports (01-02-2023)“…When listing for liver transplantation, one can transplant as soon as possible or introduce a test-of-time to better select patients, as the tumor’s biological…”
Get full text
Journal Article -
9
Management strategy after diagnosis of Abernethy malformation: a case report
Published in Journal of medical case reports (28-06-2012)“…The Abernethy malformation is a rare anomaly with a widely variable clinical presentation. Many diagnostic dilemmas have been reported. Nowadays, with the…”
Get full text
Journal Article -
10
Hand-assisted retroperitoneoscopic versus standard laparoscopic donor nephrectomy: HARP-trial
Published in BMC surgery (25-03-2010)“…Transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Live donor nephrectomy is performed on healthy…”
Get full text
Journal Article -
11
Dietary restriction and fasting downregulate complement activity
Published in BMC proceedings (01-06-2012)“…Doc number: P66…”
Get full text
Journal Article -
12
Systematic Review on the Controlling Nutritional Status (CONUT) Score in Patients Undergoing Esophagectomy for Esophageal Cancer
Published in Anticancer research (01-10-2020)“…Background/Aim: The present study aimed to examine the association of the controlling nutritional status (CONUT) score with outcomes in patients undergoing…”
Get full text
Journal Article -
13
Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules
Published in Journal of hepatology (01-10-2019)“…[Display omitted] •NK cells and cytotoxic T cells infiltrate poorly into cholangiocarcinoma.•Regulatory T cells accumulate in cholangiocarcinoma.•PD1, CTLA4…”
Get full text
Journal Article -
14
Safety and Efficacy of 166Ho Radioembolization in Hepatocellular Carcinoma: The HEPAR Primary Study
Published in The Journal of nuclear medicine (1978) (01-12-2022)“…The safety and efficacy of 166Ho radioembolization was first determined in the HEPAR and HEPAR II studies, which, however, excluded patients with…”
Get full text
Journal Article -
15
KRAS and BRAF mutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue
Published in International journal of cancer (01-07-2013)“…Although anti‐EGFR therapy has established efficacy in metastatic colorectal cancer, only 10‐20% of unselected patients respond. This is partly due to KRAS and…”
Get full text
Journal Article -
16
Machine perfusion in abdominal organ transplantation: Current use in the Netherlands
Published in World journal of transplantation (18-01-2020)“…Scarcity of donor organs and the increment in patients awaiting a transplant increased the use of organs from expanded criteria donors or donation after…”
Get full text
Journal Article -
17
Management and outcome of hepatocellular adenoma with massive bleeding at presentation
Published in World journal of gastroenterology : WJG (07-07-2017)“…To evaluate outcome of acute management and risk of rebleeding in patients with massive hemorrhage due to hepatocellular adenoma (HCA). This retrospective…”
Get full text
Journal Article -
18
Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney
Published in International journal of cancer (01-03-2015)“…Circadian clock genes regulate 10–15% of the transcriptome, and might function as tumor suppressor genes. Relatively little is known about the circadian clock…”
Get full text
Journal Article -
19
Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors
Published in Oncoimmunology (01-06-2015)“…CD4 + type 1 T regulatory (Tr1) cells have a crucial role in inducing tolerance. Immune regulation by these cells is mainly mediated through the secretion of…”
Get full text
Journal Article -
20
Impact after Live Donor Nephrectomy: A Comparative Follow-Up Study
Published in Transplantation (01-07-2018)“…INTRODUCTIONWorldwide, tens of thousands of healthy individuals participate in living kidney donation programs to help patients with end-stage renal disease…”
Get full text
Journal Article