Search Results - "IINO, Masamitsu"

Reactive astrocyte nomenclature, definitions, and future directions by Escartin, Carole, Galea, Elena, Lakatos, András, O’Callaghan, James P., Petzold, Gabor C., Serrano-Pozo, Alberto, Steinhäuser, Christian, Volterra, Andrea, Carmignoto, Giorgio, Agarwal, Amit, Allen, Nicola J., Araque, Alfonso, Barbeito, Luis, Barzilai, Ari, Bergles, Dwight E., Bonvento, Gilles, Butt, Arthur M., Chen, Wei-Ting, Cohen-Salmon, Martine, Cunningham, Colm, Deneen, Benjamin, De Strooper, Bart, Díaz-Castro, Blanca, Farina, Cinthia, Freeman, Marc, Gallo, Vittorio, Goldman, James E., Goldman, Steven A., Götz, Magdalena, Gutiérrez, Antonia, Haydon, Philip G., Heiland, Dieter H., Hol, Elly M., Holt, Matthew G., Iino, Masamitsu, Kastanenka, Ksenia V., Kettenmann, Helmut, Khakh, Baljit S., Koizumi, Schuichi, Lee, C. Justin, Liddelow, Shane A., MacVicar, Brian A., Magistretti, Pierre, Messing, Albee, Mishra, Anusha, Molofsky, Anna V., Murai, Keith K., Norris, Christopher M., Okada, Seiji, Oliet, Stéphane H. R., Oliveira, João F., Panatier, Aude, Parpura, Vladimir, Pekna, Marcela, Pekny, Milos, Pellerin, Luc, Perea, Gertrudis, Pérez-Nievas, Beatriz G., Pfrieger, Frank W., Poskanzer, Kira E., Quintana, Francisco J., Ransohoff, Richard M., Riquelme-Perez, Miriam, Robel, Stefanie, Rose, Christine R., Rothstein, Jeffrey D., Rouach, Nathalie, Rowitch, David H., Semyanov, Alexey, Sirko, Swetlana, Sontheimer, Harald, Swanson, Raymond A., Vitorica, Javier, Wanner, Ina-Beate, Wood, Levi B., Wu, Jiaqian, Zheng, Binhai, Zimmer, Eduardo R., Zorec, Robert, Sofroniew, Michael V., Verkhratsky, Alexei

“…Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional remodeling in response to injury, disease, or infection of the CNS…”
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Visualization of astrocytic intracellular Ca2+ mobilization by Okubo, Yohei, Iino, Masamitsu

“…Astrocytes generate robust intracellular Ca2+ concentration changes (Ca2+ signals), which are assumed to regulate astrocytic functions that play crucial roles…”
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Schwann cell mitochondria as key regulators in the development and maintenance of peripheral nerve axons by Ino, Daisuke, Iino, Masamitsu

“…Formation of myelin sheaths by Schwann cells (SCs) enables rapid and efficient transmission of action potentials in peripheral axons, and disruption of…”
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Red fluorescent CEPIA indicators for visualization of Ca2+ dynamics in mitochondria by Kanemaru, Kazunori, Suzuki, Junji, Taiko, Isamu, Iino, Masamitsu

“…Mitochondrial Ca 2+ dynamics are involved in the regulation of multifarious cellular processes, including intracellular Ca 2+ signalling, cell metabolism and…”
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A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing by Murakami, Tatsuya C., Mano, Tomoyuki, Saikawa, Shu, Horiguchi, Shuhei A., Shigeta, Daichi, Baba, Kousuke, Sekiya, Hiroshi, Shimizu, Yoshihiro, Tanaka, Kenji F., Kiyonari, Hiroshi, Iino, Masamitsu, Mochizuki, Hideki, Tainaka, Kazuki, Ueda, Hiroki R.

“…A three-dimensional single-cell-resolution mammalian brain atlas will accelerate systems-level identification and analysis of cellular circuits underlying…”
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Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury by Kanemaru, Kazunori, Kubota, Jun, Sekiya, Hiroshi, Hirose, Kenzo, Okubo, Yohei, Iino, Masamitsu

“…Brain injury induces phenotypic changes in astrocytes, known as reactive astrogliosis, which may influence neuronal survival. Here we show that brain injury…”
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Inositol 1,4,5‐trisphosphate receptor type 2‐independent Ca2+ release from the endoplasmic reticulum in astrocytes by Okubo, Yohei, Kanemaru, Kazunori, Suzuki, Junji, Kobayashi, Kenta, Hirose, Kenzo, Iino, Masamitsu

“…Accumulating evidence indicates that astrocytes are actively involved in the physiological and pathophysiological functions of the brain. Intracellular Ca2+…”
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Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor by Kitajima, Nami, Takikawa, Kenji, Sekiya, Hiroshi, Satoh, Kaname, Asanuma, Daisuke, Sakamoto, Hirokazu, Takahashi, Shodai, Hanaoka, Kenjiro, Urano, Yasuteru, Namiki, Shigeyuki, Iino, Masamitsu, Hirose, Kenzo

“…Adenosine 5' triphosphate (ATP) is a ubiquitous extracellular signaling messenger. Here, we describe a method for in-vivo imaging of extracellular ATP with…”
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Visualization of glutamate as a volume transmitter by Okubo, Yohei, Iino, Masamitsu

“…Glutamate is the major excitatory neurotransmitter in the central nervous system. Although glutamate mediates synaptically confined point‐to‐point…”
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Efficient Gene Transfer to Myelinating Schwann Cells in the Rodent Sciatic Nerve Using In Vivo Electroporation by Ino, Daisuke, Iino, Masamitsu

“…To study the signaling mechanism of the development and maintenance of myelinating Schwann cells (SCs) in the peripheral nervous system, in vivo techniques for…”
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Genotype-Phenotype Correlations of Malignant Hyperthermia and Central Core Disease Mutations in the Central Region of the RYR1 Channel by Murayama, Takashi, Kurebayashi, Nagomi, Ogawa, Haruo, Yamazawa, Toshiko, Oyamada, Hideto, Suzuki, Junji, Kanemaru, Kazunori, Oguchi, Katsuji, Iino, Masamitsu, Sakurai, Takashi

“…ABSTRACT Type 1 ryanodine receptor (RYR1) is a Ca2+ release channel in the sarcoplasmic reticulum of skeletal muscle and is mutated in some muscle diseases,…”
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Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR2 by Kurebayashi, Nagomi, Murayama, Takashi, Ota, Ryosaku, Suzuki, Junji, Kanemaru, Kazunori, Kobayashi, Takuya, Ohno, Seiko, Horie, Minoru, Iino, Masamitsu, Yamashita, Fumiyoshi, Sakurai, Takashi

“…Type 2 ryanodine receptor (RYR2) is a cardiac Ca2+ release channel in the ER. Mutations in RYR2 are linked to catecholaminergic polymorphic ventricular…”
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In Vivo Visualization of Subtle, Transient, and Local Activity of Astrocytes Using an Ultrasensitive Ca2+ Indicator by Kanemaru, Kazunori, Sekiya, Hiroshi, Xu, Ming, Satoh, Kaname, Kitajima, Nami, Yoshida, Keitaro, Okubo, Yohei, Sasaki, Takuya, Moritoh, Satoru, Hasuwa, Hidetoshi, Mimura, Masaru, Horikawa, Kazuki, Matsui, Ko, Nagai, Takeharu, Iino, Masamitsu, Tanaka, Kenji F.

“…Astrocytes generate local calcium (Ca2+) signals that are thought to regulate their functions. Visualization of these signals in the intact brain requires an…”
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Spatiotemporal dynamics of Ca2+ signaling and its physiological roles by IINO, Masamitsu

“…Changes in the intracellular Ca2+ concentration regulate numerous cell functions and display diverse spatiotemporal dynamics, which underlie the versatility of…”
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Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells by Okubo, Yohei, Suzuki, Junji, Kanemaru, Kazunori, Nakamura, Naotoshi, Shibata, Tatsuo, Iino, Masamitsu

“…The endoplasmic reticulum (ER) plays crucial roles in intracellular Ca(2+) signaling, serving as both a source and sink of Ca(2+), and regulating a variety of…”
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Neuronal Regulation of Schwann Cell Mitochondrial Ca2+ Signaling during Myelination by Ino, Daisuke, Sagara, Hiroshi, Suzuki, Junji, Kanemaru, Kazunori, Okubo, Yohei, Iino, Masamitsu

“…Schwann cells (SCs) myelinate peripheral neurons to promote the rapid conduction of action potentials, and the process of myelination is known to be regulated…”
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Imaging extrasynaptic glutamate dynamics in the brain by Okubo, Yohei, Sekiya, Hiroshi, Namiki, Shigeyuki, Sakamoto, Hirokazu, Iinuma, Sho, Yamasaki, Miwako, Watanabe, Masahiko, Hirose, Kenzo, Iino, Masamitsu

“…Glutamate is the major neurotransmitter in the brain, mediating point-to-point transmission across the synaptic cleft in excitatory synapses. Using a glutamate…”
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Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations by Ishii, Kiyoaki, Hirose, Kenzo, Iino, Masamitsu

“…Although many cell functions are regulated by Ca2+ oscillations induced by a cyclic release of Ca2+ from intracellular Ca2+ stores, the pacemaker mechanism of…”
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In Vivo Gene Transfer to Schwann Cells in the Rodent Sciatic Nerve by Electroporation by Ino, Daisuke, Iino, Masamitsu

“…The formation of the myelin sheath by Schwann cells (SCs) is essential for rapid conduction of nerve impulses along axons in the peripheral nervous system…”
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Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons by Kasai, Haruo, Matsuzaki, Masanori, Ellis-Davies, Graham C. R, Nemoto, Tomomi, Miyashita, Yasushi, Iino, Masamitsu

“…Dendritic spines serve as preferential sites of excitatory synaptic connections and are pleomorphic. To address the structure-function relationship of the…”
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